Population Pharmacokinetic and Pharmacodynamic Analysis of GLPG1690, an Autotaxin Inhibitor, in Healthy Volunteers and Patients with Idiopathic Pulmonary Fibrosis

por Taneja, Amit, Desrivot, Julie, Diderichsen, Paul Matthias, Blanqué, Roland, Allamasey, Lisa, Fagard, Liesbeth, Fieuw, Ann, Van der Aar, Ellen, Namour, Florence
Publicado 2019

Safety, Pharmacokinetics, and Pharmacodynamics of the Autotaxin Inhibitor GLPG1690 in Healthy Subjects: Phase 1 Randomized Trials

por van der Aar, Ellen, Desrivot, Julie, Dupont, Sonia, Heckmann, Bertrand, Fieuw, Ann, Stutvoet, Simone, Fagard, Liesbeth, Van de Wal, Karen, Helmer, Eric
Publicado 2019

The design of a randomized, placebo-controlled, dose-ranging trial to investigate the efficacy and safety of the ADAMTS-5 inhibitor S201086/GLPG1972 in knee osteoarthritis

por Imbert, Olivier, Deckx, Henri, Bernard, Katy, van der Aar, Ellen, Pueyo, Maria, Saeed, Nadeem, Fuerst, Thomas, Wirth, Wolfgang, Conaghan, Philip G., Eckstein, Felix
Publicado 2021

Safety, Pharmacokinetics, and Pharmacodynamics of the ADAMTS‐5 Inhibitor GLPG1972/S201086 in Healthy Volunteers and Participants With Osteoarthritis of the Knee or Hip

por van der Aar, Ellen, Deckx, Henri, Dupont, Sonia, Fieuw, Ann, Delage, Stephane, Larsson, Staffan, Struglics, André, Lohmander, L. Stefan, Lalande, Agnes, Leroux, Emilie, Amantini, David, Passier, Paul
Publicado 2021

The Small Molecule Ephrin Receptor Inhibitor, GLPG1790, Reduces Renewal Capabilities of Cancer Stem Cells, Showing Anti-Tumour Efficacy on Preclinical Glioblastoma Models

por Gravina, Giovanni Luca, Mancini, Andrea, Colapietro, Alessandro, Delle Monache, Simona, Sferra, Roberta, Vitale, Flora, Cristiano, Loredana, Martellucci, Stefano, Marampon, Francesco, Mattei, Vincenzo, Beirinckx, Filip, Pujuguet, Philippe, Saniere, Laurent, Lorenzon, Giocondo, van der Aar, Ellen, Festuccia, Claudio
Publicado 2019

Antitumorigenic Effects of Inhibiting Ephrin Receptor Kinase Signaling by GLPG1790 against Colorectal Cancer Cell Lines In Vitro and In Vivo

por Colapietro, Alessandro, Gravina, Giovanni Luca, Petragnano, Francesco, Fasciani, Irene, Scicchitano, Bianca Maria, Beirinckx, Filip, Pujuguet, Philippe, Saniere, Laurent, Van der Aar, Ellen, Musio, Daniela, De Felice, Francesca, Mattei, Vincenzo, Martellucci, Stefano, Maggio, Roberto, Tombolini, Vincenzo, Festuccia, Claudio, Marampon, Francesco
Publicado 2020