A novel Drosophila SOD2 mutant demonstrates a role for mitochondrial ROS in neurodevelopment and disease

por Celotto, Alicia M, Liu, Zhaohui, VanDemark, Andrew P, Palladino, Michael J
Publicado 2012

The interaction between Shroom3 and Rho-kinase is required for neural tube morphogenesis in mice

por Das, Debamitra, Zalewski, Jenna K., Mohan, Swarna, Plageman, Timothy F., VanDemark, Andrew P., Hildebrand, Jeffrey D.
Publicado 2014

Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Rad52

por Gaines, William A., Godin, Stephen K., Kabbinavar, Faiz F., Rao, Timsi, VanDemark, Andrew P., Sung, Patrick, Bernstein, Kara A.
Publicado 2015

Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction

por Mohan, Swarna, Rizaldy, Ryan, Das, Debamitra, Bauer, Robert J., Heroux, Annie, Trakselis, Michael A., Hildebrand, Jeffrey D., VanDemark, Andrew P.
Publicado 2012

The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55–Rad57 to mediate error-free recombination

por Godin, Stephen, Wier, Adam, Kabbinavar, Faiz, Bratton-Palmer, Dominique S., Ghodke, Harshad, Van Houten, Bennett, VanDemark, Andrew P., Bernstein, Kara A.
Publicado 2013

Characterization of Differential Dynamics, Specificity, and Allostery of Lipoxygenase Family Members

por Mikulska-Ruminska, Karolina, Shrivastava, Indira, Krieger, James, Zhang, She, Li, Hongchun, Bayır, Hülya, Wenzel, Sally E., VanDemark, Andrew P., Kagan, Valerian E., Bahar, Ivet
Publicado 2019

Itavastatin and resveratrol increase triosephosphate isomerase protein in a newly identified variant of TPI deficiency

por VanDemark, Andrew P., Hrizo, Stacy L., Eicher, Samantha L., Kowalski, Jules, Myers, Tracey D., Pfeifer, Megan R., Riley, Kacie N., Koeberl, Dwight D., Palladino, Michael J.
Publicado 2022

Structure of a Highly Conserved Domain of Rock1 Required for Shroom-Mediated Regulation of Cell Morphology

por Mohan, Swarna, Das, Debamitra, Bauer, Robert J., Heroux, Annie, Zalewski, Jenna K., Heber, Simone, Dosunmu-Ogunbi, Atinuke M., Trakselis, Michael A., Hildebrand, Jeffrey D., VanDemark, Andrew P.
Publicado 2013

Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics

por Roland, Bartholomew P., Zeccola, Alison M., Larsen, Samantha B., Amrich, Christopher G., Talsma, Aaron D., Stuchul, Kimberly A., Heroux, Annie, Levitan, Edwin S., VanDemark, Andrew P., Palladino, Michael J.
Publicado 2016

Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis

por Anthonymuthu, Tamil S., Tyurina, Yulia Y., Sun, Wan-Yang, Mikulska-Ruminska, Karolina, Shrivastava, Indira H., Tyurin, Vladimir A., Cinemre, Fatma B., Dar, Haider H., VanDemark, Andrew P., Holman, Theodore R., Sadovsky, Yoel, Stockwell, Brent R., He, Rong-Rong, Bahar, Ivet, Bayır, Hülya, Kagan, Valerian E.
Publicado 2020

On the illusion of auxotrophy: met15Δ yeast cells can grow on inorganic sulfur, thanks to the previously uncharacterized homocysteine synthase Yll058w

por Van Oss, S. Branden, Parikh, Saurin Bipin, Castilho Coelho, Nelson, Wacholder, Aaron, Belashov, Ivan, Zdancewicz, Sara, Michaca, Manuel, Xu, Jiazhen, Kang, Yun Pyo, Ward, Nathan P., Yoon, Sang Jun, McCourt, Katherine M., McKee, Jake, Ideker, Trey, VanDemark, Andrew P., DeNicola, Gina M., Carvunis, Anne-Ruxandra
Publicado 2022

The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway

por Rosenbaum, Joel C., Bonilla, Braulio, Hengel, Sarah R., Mertz, Tony M., Herken, Benjamin W., Kazemier, Hinke G., Pressimone, Catherine A., Ratterman, Timothy C., MacNary, Ellen, De Magis, Alessio, Kwon, Youngho, Godin, Stephen K., Van Houten, Bennett, Normolle, Daniel P., Sung, Patrick, Das, Subha R., Paeschke, Katrin, Roberts, Steven A., VanDemark, Andrew P., Bernstein, Kara A.
Publicado 2019

Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death

por Lamade, Andrew M., Wu, Limin, Dar, Haider H., Mentrup, Heather L., Shrivastava, Indira H., Epperly, Michael W., St Croix, Claudette M., Tyurina, Yulia Y., Anthonymuthu, Tamil S., Yang, Qin, Kapralov, Aleksandr A., Huang, Zhentai, Mao, Gaowei, Amoscato, Andrew A., Hier, Zachary E., Artyukhova, Margarita A., Shurin, Galina, Rosenbaum, Joel C., Gough, Peter J., Bertin, John, VanDemark, Andrew P., Watkins, Simon C., Mollen, Kevin P., Bahar, Ivet, Greenberger, Joel S., Kagan, Valerian E., Whalen, Michael J., Bayır, Hülya
Publicado 2022