Allosteric inhibition explained through conformational ensembles sampling distinct “mixed” states

por Byun, Jung Ah, VanSchouwen, Bryan, Akimoto, Madoka, Melacini, Giuseppe
Publicado 2020

Divergent allostery reveals critical differences between structurally homologous regulatory domains of Plasmodium falciparum and human protein kinase G

por Byun, Jung Ah, VanSchouwen, Bryan, Huang, Jinfeng, Baryar, Ubaidullah, Melacini, Giuseppe
Publicado 2022

State-selective frustration as a key driver of allosteric pluripotency

por Byun, Jung Ah, VanSchouwen, Bryan, Parikh, Nishi, Akimoto, Madoka, McNicholl, Eric Tyler, Melacini, Giuseppe
Publicado 2021

Distance-Based Configurational Entropy of Proteins from Molecular Dynamics Simulations

por Fogolari, Federico, Corazza, Alessandra, Fortuna, Sara, Soler, Miguel Angel, VanSchouwen, Bryan, Brancolini, Giorgia, Corni, Stefano, Melacini, Giuseppe, Esposito, Gennaro
Publicado 2015

An auto-inhibited state of protein kinase G and implications for selective activation

por Sharma, Rajesh, Kim, Jeong Joo, Qin, Liying, Henning, Philipp, Akimoto, Madoka, VanSchouwen, Bryan, Kaur, Gundeep, Sankaran, Banumathi, MacKenzie, Kevin R, Melacini, Giuseppe, Casteel, Darren E, Herberg, Friedrich W, Kim, Choel
Publicado 2022

Structures of human PKG reveal cGMP-selectived activation mechanisms

por Huang, Gilbert Y, Kim, Jeong J, Reger, Albert S, Lorenz, Robin, Moon, Eui-Whan, Zhao, Chi, Casteel, Darren E, Bertinetti, Daniela, VanSchouwen, Bryan, Selvaratnam, Rajeevan, Pflugrath, James W, Sankaran, Banumathi, Melacini, Giuseppe, Herberg, Friedrich W, Kim, Choel
Publicado 2013