The “Common Soil Hypothesis” Revisited—Risk Factors for Type 2 Diabetes and Cardiovascular Disease

por Fernandes Silva, Lilian, Vangipurapu, Jagadish, Laakso, Markku
Publicado 2021

An intronic variant in the GCKR gene is associated with multiple lipids

por Fernandes Silva, Lilian, Vangipurapu, Jagadish, Kuulasmaa, Teemu, Laakso, Markku
Publicado 2019

Metabolite Signature of Simvastatin Treatment Involves Multiple Metabolic Pathways

por Fernandes Silva, Lilian, Ravi, Rowmika, Vangipurapu, Jagadish, Laakso, Markku
Publicado 2022

Both Fasting and Glucose-Stimulated Proinsulin Levels Predict Hyperglycemia and Incident Type 2 Diabetes: A Population-Based Study of 9,396 Finnish Men

por Vangipurapu, Jagadish, Stančáková, Alena, Kuulasmaa, Teemu, Kuusisto, Johanna, Laakso, Markku
Publicado 2015

Effects of SLCO1B1 Genetic Variant on Metabolite Profile in Participants on Simvastatin Treatment

por Fernandes Silva, Lilian, Ravi, Rowmika, Vangipurapu, Jagadish, Oravilahti, Anniina, Laakso, Markku
Publicado 2022

Plasma Metabolite Signatures in Male Carriers of Genetic Variants Associated with Non-Alcoholic Fatty Liver Disease

por Fernandes Silva, Lilian, Vangipurapu, Jagadish, Oravilahti, Anniina, Männistö, Ville, Laakso, Markku
Publicado 2023

The Association of 9 Amino Acids With Cardiovascular Events in Finnish Men in a 12-Year Follow-up Study

por Jauhiainen, Raimo, Vangipurapu, Jagadish, Laakso, Annamaria, Kuulasmaa, Teemu, Kuusisto, Johanna, Laakso, Markku
Publicado 2021

Novel biomarkers associated with incident heart failure in 10 106 Finnish men

por Jauhiainen, Raimo, Jauhiainen, Matti, Vangipurapu, Jagadish, Kuulasmaa, Teemu, Ala‐Korpela, Mika, Laakso, Markku, Kuusisto, Johanna
Publicado 2020

Metabolite Signature in the Carriers of Pathogenic Genetic Variants for Cardiomyopathy: A Population-Based METSIM Study

por Ravi, Rowmika, Fernandes Silva, Lilian, Vangipurapu, Jagadish, Maria, Maleeha, Raivo, Joose, Helisalmi, Seppo, Laakso, Markku
Publicado 2022

Markers of Tissue-Specific Insulin Resistance Predict the Worsening of Hyperglycemia, Incident Type 2 Diabetes and Cardiovascular Disease

por FízeI'ová, Mária, Cederberg, Henna, Stančáková, Alena, Jauhiainen, Raimo, Vangipurapu, Jagadish, Kuusisto, Johanna, Laakso, Markku
Publicado 2014

Functional Variant in the GCKR Gene Affects Lactate Levels Differentially in the Fasting State and During Hyperglycemia

por López Rodríguez, Maykel, Fernandes Silva, Lilian, Vangipurapu, Jagadish, Modi, Shalem, Kuusisto, Johanna, Kaikkonen, Minna U., Laakso, Markku
Publicado 2018

Glycerol and Fatty Acids in Serum Predict the Development of Hyperglycemia and Type 2 Diabetes in Finnish Men

por Mahendran, Yuvaraj, Cederberg, Henna, Vangipurapu, Jagadish, Kangas, Antti J., Soininen, Pasi, Kuusisto, Johanna, Uusitupa, Matti, Ala-Korpela, Mika, Laakso, Markku
Publicado 2013

Non-Cholesterol Sterol Levels Predict Hyperglycemia and Conversion to Type 2 Diabetes in Finnish Men

por Cederberg, Henna, Gylling, Helena, Miettinen, Tatu A., Paananen, Jussi, Vangipurapu, Jagadish, Pihlajamäki, Jussi, Kuulasmaa, Teemu, Stančáková, Alena, Smith, Ulf, Kuusisto, Johanna, Laakso, Markku
Publicado 2013

Genetic basis and outcome in a nationwide study of Finnish patients with hypertrophic cardiomyopathy

por Jääskeläinen, Pertti, Vangipurapu, Jagadish, Raivo, Joose, Kuulasmaa, Teemu, Heliö, Tiina, Aalto‐Setälä, Katriina, Kaartinen, Maija, Ilveskoski, Erkki, Vanninen, Sari, Hämäläinen, Liisa, Melin, John, Kokkonen, Jorma, Nieminen, Markku S., Laakso, Markku, Kuusisto, Johanna
Publicado 2019

Association of Ketone Body Levels With Hyperglycemia and Type 2 Diabetes in 9,398 Finnish Men

por Mahendran, Yuvaraj, Vangipurapu, Jagadish, Cederberg, Henna, Stančáková, Alena, Pihlajamäki, Jussi, Soininen, Pasi, Kangas, Antti J., Paananen, Jussi, Civelek, Mete, Saleem, Niyas K., Pajukanta, Päivi, Lusis, Aldons J., Bonnycastle, Lori L., Morken, Mario A., Collins, Francis S., Mohlke, Karen L., Boehnke, Michael, Ala-Korpela, Mika, Kuusisto, Johanna, Laakso, Markku
Publicado 2013

Detection of Novel Gene Variants Associated with Congenital Hypothyroidism in a Finnish Patient Cohort

por Löf, Christoffer, Patyra, Konrad, Kuulasmaa, Teemu, Vangipurapu, Jagadish, Undeutsch, Henriette, Jaeschke, Holger, Pajunen, Tuulia, Kero, Andreina, Krude, Heiko, Biebermann, Heike, Kleinau, Gunnar, Kühnen, Peter, Rantakari, Krista, Miettinen, Päivi, Kirjavainen, Turkka, Pursiheimo, Juha-Pekka, Mustila, Taina, Jääskeläinen, Jarmo, Ojaniemi, Marja, Toppari, Jorma, Ignatius, Jaakko, Laakso, Markku, Kero, Jukka
Publicado 2016

Mitochondrial genome copy number measured by DNA sequencing in human blood is strongly associated with metabolic traits via cell-type composition differences

por Ganel, Liron, Chen, Lei, Christ, Ryan, Vangipurapu, Jagadish, Young, Erica, Das, Indraniel, Kanchi, Krishna, Larson, David, Regier, Allison, Abel, Haley, Kang, Chul Joo, Scott, Alexandra, Havulinna, Aki, Chiang, Charleston W. K., Service, Susan, Freimer, Nelson, Palotie, Aarno, Ripatti, Samuli, Kuusisto, Johanna, Boehnke, Michael, Laakso, Markku, Locke, Adam, Stitziel, Nathan O., Hall, Ira M.
Publicado 2021

Exome sequencing of Finnish isolates enhances rare-variant association power

por Locke, Adam E, Steinberg, Karyn Meltz, Chiang, Charleston WK, Service, Susan K, Havulinna, Aki S, Stell, Laurel, Pirinen, Matti, Abel, Haley J, Chiang, Colby C, Fulton, Robert S, Jackson, Anne U, Kang, Chul Joo, Kanchi, Krishna L, Koboldt, Daniel C, Larson, David E, Nelson, Joanne, Nicholas, Thomas J, Pietilä, Arto, Ramensky, Vasily, Ray, Debashree, Scott, Laura J, Stringham, Heather M, Vangipurapu, Jagadish, Welch, Ryan, Yajnik, Pranav, Yin, Xianyong, Eriksson, Johan G, Ala-Korpela, Mika, Järvelin, Marjo-Riitta, Männikkö, Minna, Laivuori, Hannele, Dutcher, Susan K, Stitziel, Nathan O, Wilson, Richard K, Hall, Ira M, Sabatti, Chiara, Palotie, Aarno, Salomaa, Veikko, Laakso, Markku, Ripatti, Samuli, Boehnke, Michael, Freimer, Nelson B
Publicado 2019

Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study

por Gudmundsdottir, Valborg, Pedersen, Helle Krogh, Mazzoni, Gianluca, Allin, Kristine H., Artati, Anna, Beulens, Joline W., Banasik, Karina, Brorsson, Caroline, Cederberg, Henna, Chabanova, Elizaveta, De Masi, Federico, Elders, Petra J., Forgie, Ian, Giordano, Giuseppe N., Grallert, Harald, Gupta, Ramneek, Haid, Mark, Hansen, Torben, Hansen, Tue H., Hattersley, Andrew T., Heggie, Alison, Hong, Mun-Gwan, Jones, Angus G., Koivula, Robert, Kokkola, Tarja, Laakso, Markku, Løngreen, Peter, Mahajan, Anubha, Mari, Andrea, McDonald, Timothy J., McEvoy, Donna, Musholt, Petra B., Pavo, Imre, Prehn, Cornelia, Ruetten, Hartmut, Ridderstråle, Martin, Rutters, Femke, Sharma, Sapna, Slieker, Roderick C., Syed, Ali, Tajes, Juan Fernandez, Thomas, Cecilia Engel, Thomsen, Henrik S., Vangipurapu, Jagadish, Vestergaard, Henrik, Viñuela, Ana, Wesolowska-Andersen, Agata, Walker, Mark, Adamski, Jerzy, Schwenk, Jochen M., McCarthy, Mark I., Pearson, Ewan, Dermitzakis, Emmanouil, Franks, Paul W., Pedersen, Oluf, Brunak, Søren
Publicado 2020

Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits

por Brown, Andrew A., Fernandez-Tajes, Juan J., Hong, Mun-gwan, Brorsson, Caroline A., Koivula, Robert W., Davtian, David, Dupuis, Théo, Sartori, Ambra, Michalettou, Theodora-Dafni, Forgie, Ian M., Adam, Jonathan, Allin, Kristine H., Caiazzo, Robert, Cederberg, Henna, De Masi, Federico, Elders, Petra J. M., Giordano, Giuseppe N., Haid, Mark, Hansen, Torben, Hansen, Tue H., Hattersley, Andrew T., Heggie, Alison J., Howald, Cédric, Jones, Angus G., Kokkola, Tarja, Laakso, Markku, Mahajan, Anubha, Mari, Andrea, McDonald, Timothy J., McEvoy, Donna, Mourby, Miranda, Musholt, Petra B., Nilsson, Birgitte, Pattou, Francois, Penet, Deborah, Raverdy, Violeta, Ridderstråle, Martin, Romano, Luciana, Rutters, Femke, Sharma, Sapna, Teare, Harriet, ‘t Hart, Leen, Tsirigos, Konstantinos D., Vangipurapu, Jagadish, Vestergaard, Henrik, Brunak, Søren, Franks, Paul W., Frost, Gary, Grallert, Harald, Jablonka, Bernd, McCarthy, Mark I., Pavo, Imre, Pedersen, Oluf, Ruetten, Hartmut, Walker, Mark, Adamski, Jerzy, Schwenk, Jochen M., Pearson, Ewan R., Dermitzakis, Emmanouil T., Viñuela, Ana
Publicado 2023