Phosphoinositide lipids in primary cilia biology

por Conduit, Sarah E., Vanhaesebroeck, Bart
Publicado 2020

Antigen receptor signalling: a distinctive role for the p110δ isoform of PI3K

por Okkenhaug, Klaus, Ali, Khaled, Vanhaesebroeck, Bart
Publicado 2007

Michael D. Waterfield

por Downward, Julian, Parker, Peter J., Vanhaesebroeck, Bart
Publicado 2023

Sequential targeting of PI3Kδ and LAG3 as an effective anti-cancer approach

por Lauder, Sarah N., Vanhaesebroeck, Bart, Gallimore, Awen
Publicado 2021

Autocrine Tumor Necrosis Factor (TNF) and Lymphotoxin (LT) α Differentially Modulate Cellular Sensitivity to TNF/LT-α Cytotoxicity in L929 Cells

por Decoster, Els, Cornelis, Sigrid, Vanhaesebroeck, Bart, Fiers, Walter
Publicado 1998

The p110δ of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generation

por Guo, Hailong, Samarakoon, Asanga, Vanhaesebroeck, Bart, Malarkannan, Subramaniam
Publicado 2008

The PI3K p110α isoform regulates endothelial adherens junctions via Pyk2 and Rac1

por Cain, Robert J., Vanhaesebroeck, Bart, Ridley, Anne J.
Publicado 2010

Cancer-Associated PIK3CA Mutations in Overgrowth Disorders

por Madsen, Ralitsa R., Vanhaesebroeck, Bart, Semple, Robert K.
Publicado 2018

Isoform-selective induction of human p110δ PI3K expression by TNFα: identification of a new and inducible PIK3CD promoter

por Whitehead, Maria A., Bombardieri, Michele, Pitzalis, Costantino, Vanhaesebroeck, Bart
Publicado 2012

PI3Kα in cardioprotection: Cytoskeleton, late Na(+) current, and mechanism of arrhythmias

por Zhabyeyev, Pavel, Chen, Xueyi, Vanhaesebroeck, Bart, Oudit, Gavin Y.
Publicado 2019

Syndecan-2 is a novel ligand for the protein tyrosine phosphatase receptor CD148

por Whiteford, James R., Xian, Xiaojie, Chaussade, Claire, Vanhaesebroeck, Bart, Nourshargh, Sussan, Couchman, John R.
Publicado 2011

Both p110α and p110β isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor

por Berenjeno, Inma M., Guillermet-Guibert, Julie, Pearce, Wayne, Gray, Alexander, Fleming, Stewart, Vanhaesebroeck, Bart
Publicado 2012

Perspective: Potential Impact and Therapeutic Implications of Oncogenic PI3K Activation on Chromosomal Instability

por Vanhaesebroeck, Bart, Bilanges, Benoit, Madsen, Ralitsa R., Dale, Katie L., Lau, Evelyn, Vladimirou, Elina
Publicado 2019

The role of PI3Kα isoform in cardioprotection

por Rossello, Xavier, Riquelme, Jaime A., He, Zhenhe, Taferner, Stasa, Vanhaesebroeck, Bart, Davidson, Sean M., Yellon, Derek M.
Publicado 2017

Long-term p110α PI3K inactivation exerts a beneficial effect on metabolism

por Foukas, Lazaros C, Bilanges, Benoit, Bettedi, Lucia, Pearce, Wayne, Ali, Khaled, Sancho, Sara, Withers, Dominic J, Vanhaesebroeck, Bart
Publicado 2013

Fyn-ADAP signaling via Carma1-Bcl10-MAP3K7 signalosome exclusively regulates inflammatory cytokine production in NK cells

por Rajasekaran, Kamalakannan, Kumar, Pawan, Schuldt, Kristina M., Peterson, Erik J., Vanhaesebroeck, Bart, Dixit, Vishva, Thakar, Monica S., Malarkannan, Subramaniam
Publicado 2013

Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice

por Alliouachene, Samira, Bilanges, Benoit, Chaussade, Claire, Pearce, Wayne, Foukas, Lazaros C., Scudamore, Cheryl L., Moniz, Larissa S., Vanhaesebroeck, Bart
Publicado 2016

Inactivating the lipid kinase activity of PI3KC2β is sufficient to rescue myotubular myopathy in mice

por Massana-Muñoz, Xènia, Goret, Marie, Nattarayan, Vasugi, Reiss, David, Kretz, Christine, Chicanne, Gaetan, Payrastre, Bernard, Vanhaesebroeck, Bart, Laporte, Jocelyn
Publicado 2023

Regulation of p110δ PI 3-Kinase Gene Expression

por Kok, Klaartje, Nock, Gemma E., Verrall, Elizabeth A. G., Mitchell, Michael P., Hommes, Daan W., Peppelenbosch, Maikel P., Vanhaesebroeck, Bart
Publicado 2009

Positive correlation between transcriptomic stemness and PI3K/AKT/mTOR signaling scores in breast cancer, and a counterintuitive relationship with PIK3CA genotype

por Madsen, Ralitsa R., Erickson, Emily C., Rueda, Oscar M., Robin, Xavier, Caldas, Carlos, Toker, Alex, Semple, Robert K., Vanhaesebroeck, Bart
Publicado 2021