Prediction of Function Determining and Buried Residues Through Analysis of Saturation Mutagenesis Datasets

por Bhasin, Munmun, Varadarajan, Raghavan
Publicado 2021

Molecular bases for strong phenotypic effects of single synonymous codon substitutions in the E. coli ccdB toxin gene

por Bajaj, Priyanka, Bhasin, Munmun, Varadarajan, Raghavan
Publicado 2023

Rapid Identification of Secondary Structure and Binding Site Residues in an Intrinsically Disordered Protein Segment

por Chandra, Soumyanetra, Chattopadhyay, Gopinath, Varadarajan, Raghavan
Publicado 2021

DEPTH: a web server to compute depth and predict small-molecule binding cavities in proteins

por Tan, Kuan Pern, Varadarajan, Raghavan, Madhusudhan, M. S.
Publicado 2011

Prediction of Residue-specific Contributions to Binding and Thermal Stability Using Yeast Surface Display

por Ahmed, Shahbaz, Bhasin, Munmun, Manjunath, Kavyashree, Varadarajan, Raghavan
Publicado 2022

Identification of stabilizing point mutations through mutagenesis of destabilized protein libraries

por Ahmed, Shahbaz, Manjunath, Kavyashree, Chattopadhyay, Gopinath, Varadarajan, Raghavan
Publicado 2022

TSpred: a web server for the rational design of temperature-sensitive mutants

por Tan, Kuan Pern, Khare, Shruti, Varadarajan, Raghavan, Madhusudhan, Mallur Srivatsan
Publicado 2014

Residue proximity information and protein model discrimination using saturation-suppressor mutagenesis

por Sahoo, Anusmita, Khare, Shruti, Devanarayanan, Sivasankar, Jain, Pankaj C., Varadarajan, Raghavan
Publicado 2015

Depth: a web server to compute depth, cavity sizes, detect potential small-molecule ligand-binding cavities and predict the pK(a) of ionizable residues in proteins

por Tan, Kuan Pern, Nguyen, Thanh Binh, Patel, Siddharth, Varadarajan, Raghavan, Madhusudhan, M. S.
Publicado 2013

Mechanistic insights into global suppressors of protein folding defects

por Chattopadhyay, Gopinath, Bhowmick, Jayantika, Manjunath, Kavyashree, Ahmed, Shahbaz, Goyal, Parveen, Varadarajan, Raghavan
Publicado 2022

Biophysical Correlates of Enhanced Immunogenicity of a Stabilized Variant of the Receptor Binding Domain of SARS-CoV-2

por Kanjo, Kawkab, Chattopadhyay, Gopinath, Malladi, Sameer Kumar, Singh, Randhir, Jayatheertha, Sowrabha, Varadarajan, Raghavan
Publicado 2023

Stereochemical Criteria for Prediction of the Effects of Proline Mutations on Protein Stability

por Bajaj, Kanika, Madhusudhan, M. S, Adkar, Bharat V, Chakrabarti, Purbani, Ramakrishnan, C, Sali, Andrej, Varadarajan, Raghavan
Publicado 2007

The High Mutational Sensitivity of ccdA Antitoxin Is Linked to Codon Optimality

por Chandra, Soumyanetra, Gupta, Kritika, Khare, Shruti, Kohli, Pehu, Asok, Aparna, Mohan, Sonali Vishwa, Gowda, Harsha, Varadarajan, Raghavan
Publicado 2022

Hemagglutinin Sequence Conservation Guided Stem Immunogen Design from Influenza A H3 Subtype

por Mallajosyula, V. Vamsee Aditya, Citron, Michael, Ferrara, Francesca, Temperton, Nigel J., Liang, Xiaoping, Flynn, Jessica A., Varadarajan, Raghavan
Publicado 2015

Isolation of a High Affinity Neutralizing Monoclonal Antibody against 2009 Pandemic H1N1 Virus That Binds at the ‘Sa’ Antigenic Site

por Shembekar, Nachiket, Mallajosyula, Vamsee V. Aditya, Mishra, Arpita, Yeolekar, Leena, Dhere, Rajeev, Kapre, Subhash, Varadarajan, Raghavan, Gupta, Satish Kumar
Publicado 2013

One-step sequence and structure-guided optimization of HIV-1 envelope gp140

por Malladi, Sameer Kumar, Schreiber, David, Pramanick, Ishika, Sridevi, Malavika Abhineshababu, Goldenzweig, Adi, Dutta, Somnath, Fleishman, Sarel Jacob, Varadarajan, Raghavan
Publicado 2020

Effect of Signal Peptide on Stability and Folding of Escherichia coli Thioredoxin

por Singh, Pranveer, Sharma, Likhesh, Kulothungan, S. Rajendra, Adkar, Bharat V., Prajapati, Ravindra Singh, Ali, P. Shaik Syed, Krishnan, Beena, Varadarajan, Raghavan
Publicado 2013

Molecular Determinants of Mutant Phenotypes, Inferred from Saturation Mutagenesis Data

por Tripathi, Arti, Gupta, Kritika, Khare, Shruti, Jain, Pankaj C., Patel, Siddharth, Kumar, Prasanth, Pulianmackal, Ajai J., Aghera, Nilesh, Varadarajan, Raghavan
Publicado 2016

VapC21 Toxin Contributes to Drug-Tolerance and Interacts With Non-cognate VapB32 Antitoxin in Mycobacterium tuberculosis

por Sharma, Arun, Chattopadhyay, Gopinath, Chopra, Pankaj, Bhasin, Munmun, Thakur, Chandrani, Agarwal, Sakshi, Ahmed, Shahbaz, Chandra, Nagasuma, Varadarajan, Raghavan, Singh, Ramandeep
Publicado 2020

Protective Efficacy of Recombinant Influenza Hemagglutinin Ectodomain Fusions

por Mittal, Nidhi, Sengupta, Nayanika, Malladi, Sameer Kumar, Reddy, Poorvi, Bhat, Madhuraj, Rajmani, Raju S., Sedeyn, Koen, Saelens, Xavier, Dutta, Somnath, Varadarajan, Raghavan
Publicado 2021