Computational Docking of Antibody-Antigen Complexes, Opportunities and Pitfalls Illustrated by Influenza Hemagglutinin

por Pedotti, Mattia, Simonelli, Luca, Livoti, Elsa, Varani, Luca
Publicado 2011

Opening Study on the Development of a New Biosensor for Metal Toxicity Based on Pseudomonas fluorescens Pyoverdine

por Chiadò, Alessandro, Varani, Luca, Bosco, Francesca, Marmo, Luca
Publicado 2013

Differential expression and biochemical activity of the immune receptor Tim-3 in healthy and malignant human myeloid cells

por Silva, Isabel Gonçalves, Gibbs, Bernhard F., Bardelli, Marco, Varani, Luca, Sumbayev, Vadim V.
Publicado 2015

Rational engineering of the lccβ T. versicolor laccase for the mediator-less oxidation of large polycyclic aromatic hydrocarbons

por Chiadò, Alessandro, Bosco, Francesca, Bardelli, Marco, Simonelli, Luca, Pedotti, Mattia, Marmo, Luca, Varani, Luca
Publicado 2021

Rational Engineering of a Human Anti-Dengue Antibody through Experimentally Validated Computational Docking

por Simonelli, Luca, Pedotti, Mattia, Beltramello, Martina, Livoti, Elsa, Calzolai, Luigi, Sallusto, Federica, Lanzavecchia, Antonio, Varani, Luca
Publicado 2013

Rational Modification of Estrogen Receptor by Combination of Computational and Experimental Analysis

por Ferrero, Valentina Elisabetta Viviana, Pedotti, Mattia, Chiadò, Alessandro, Simonelli, Luca, Calzolai, Luigi, Varani, Luca, Lettieri, Teresa
Publicado 2014

Rationally Modified Estrogen Receptor Protein as a Bio-Recognition Element for the Detection of EDC Pollutants: Strategies and Opportunities

por Pedotti, Mattia, Ferrero, Valentina Elisabetta Viviana, Lettieri, Teresa, Colpo, Pascal, Follonier, Stephane, Calzolai, Luigi, Varani, Luca
Publicado 2015

Analytical Ultracentrifugation Detects Quaternary Rearrangements and Antibody-Induced Conformational Selection of the SARS-CoV-2 Spike Trimer

por Guerrini, Giuditta, Mehn, Dora, Fumagalli, Francesco, Gioria, Sabrina, Pedotti, Mattia, Simonelli, Luca, Bianchini, Filippo, Robbiani, Davide F., Varani, Luca, Calzolai, Luigi
Publicado 2023

Label-Free Biosensor Detection of Endocrine Disrupting Compounds Using Engineered Estrogen Receptors

por La Spina, Rita, Ferrero, Valentina E. V., Aiello, Venera, Pedotti, Mattia, Varani, Luca, Lettieri, Teresa, Calzolai, Luigi, Haasnoot, Willem, Colpo, Pascal
Publicado 2017

The immune receptor Tim-3 acts as a trafficker in a Tim-3/galectin-9 autocrine loop in human myeloid leukemia cells

por Gonçalves Silva, Isabel, Rüegg, Laura, Gibbs, Bernhard F., Bardelli, Marco, Fruehwirth, Alexander, Varani, Luca, Berger, Steffen M., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Publicado 2016

Effects of Antibody Responses to Pre-Existing Coronaviruses on Disease Severity and Complement Activation in COVID-19 Patients

por Cugno, Massimo, Meroni, Pier Luigi, Consonni, Dario, Griffini, Samantha, Grovetti, Elena, Novembrino, Cristina, Torri, Adriana, Griffante, Gloria, Gariglio, Marisa, Varani, Luca, Peyvandi, Flora
Publicado 2022

A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity

por Bardelli, Marco, Frontzek, Karl, Simonelli, Luca, Hornemann, Simone, Pedotti, Mattia, Mazzola, Federica, Carta, Manfredi, Eckhardt, Valeria, D’Antuono, Rocco, Virgilio, Tommaso, González, Santiago F., Aguzzi, Adriano, Varani, Luca
Publicado 2018

Experimental evidence for long-distance electrodynamic intermolecular forces

por Lechelon, Mathias, Meriguet, Yoann, Gori, Matteo, Ruffenach, Sandra, Nardecchia, Ilaria, Floriani, Elena, Coquillat, Dominique, Teppe, Frédéric, Mailfert, Sébastien, Marguet, Didier, Ferrier, Pierre, Varani, Luca, Sturgis, James, Torres, Jeremie, Pettini, Marco
Publicado 2022

Machine learning analyses of antibody somatic mutations predict immunoglobulin light chain toxicity

por Garofalo, Maura, Piccoli, Luca, Romeo, Margherita, Barzago, Maria Monica, Ravasio, Sara, Foglierini, Mathilde, Matkovic, Milos, Sgrignani, Jacopo, De Gasparo, Raoul, Prunotto, Marco, Varani, Luca, Diomede, Luisa, Michielin, Olivier, Lanzavecchia, Antonio, Cavalli, Andrea
Publicado 2021

Adapting Neutralizing Antibodies to Viral Variants by Structure‐Guided Affinity Maturation Using Phage Display Technology

por Peissert, Frederik, Pedotti, Mattia, Corbellari, Riccardo, Simonelli, Luca, De Gasparo, Raoul, Tamagnini, Elia, Plüss, Louis, Elsayed, Abdullah, Matasci, Mattia, De Luca, Roberto, Cassaniti, Irene, Sammartino, Jose’ Camilla, Piralla, Antonio, Baldanti, Fausto, Neri, Dario, Varani, Luca
Publicado 2023

HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4

por Schiraldi, Milena, Raucci, Angela, Muñoz, Laura Martínez, Livoti, Elsa, Celona, Barbara, Venereau, Emilie, Apuzzo, Tiziana, De Marchis, Francesco, Pedotti, Mattia, Bachi, Angela, Thelen, Marcus, Varani, Luca, Mellado, Mario, Proudfoot, Amanda, Bianchi, Marco Emilio, Uguccioni, Mariagrazia
Publicado 2012

High mobility group box 1 (HMGB1) acts as an “alarmin” to promote acute myeloid leukaemia progression

por Yasinska, Inna M., Gonçalves Silva, Isabel, Sakhnevych, Svetlana S., Ruegg, Laura, Hussain, Rohanah, Siligardi, Giuliano, Fiedler, Walter, Wellbrock, Jasmin, Bardelli, Marco, Varani, Luca, Raap, Ulrike, Berger, Steffen, Gibbs, Bernhard F., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Publicado 2018

The Tim-3-galectin-9 Secretory Pathway is Involved in the Immune Escape of Human Acute Myeloid Leukemia Cells

por Gonçalves Silva, Isabel, Yasinska, Inna M., Sakhnevych, Svetlana S., Fiedler, Walter, Wellbrock, Jasmin, Bardelli, Marco, Varani, Luca, Hussain, Rohanah, Siligardi, Giuliano, Ceccone, Giacomo, Berger, Steffen M., Ushkaryov, Yuri A., Gibbs, Bernhard F., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Publicado 2017

Ligand-Receptor Interactions of Galectin-9 and VISTA Suppress Human T Lymphocyte Cytotoxic Activity

por Yasinska, Inna M., Meyer, N. Helge, Schlichtner, Stephanie, Hussain, Rohanah, Siligardi, Giuliano, Casely-Hayford, Maxwell, Fiedler, Walter, Wellbrock, Jasmin, Desmet, Cloe, Calzolai, Luigi, Varani, Luca, Berger, Steffen M., Raap, Ulrike, Gibbs, Bernhard F., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Publicado 2020

Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release

por Venereau, Emilie, Casalgrandi, Maura, Schiraldi, Milena, Antoine, Daniel J., Cattaneo, Angela, De Marchis, Francesco, Liu, Jaron, Antonelli, Antonella, Preti, Alessandro, Raeli, Lorenzo, Shams, Sara Samadi, Yang, Huan, Varani, Luca, Andersson, Ulf, Tracey, Kevin J., Bachi, Angela, Uguccioni, Mariagrazia, Bianchi, Marco E.
Publicado 2012