Alcohol, DNA Methylation, and Cancer

por Varela-Rey, Marta, Woodhoo, Ashwin, Martinez-Chantar, Maria-Luz, Mato, José M., Lu, Shelly C.
Publicado 2013

Ubiquitin-Like Post-Translational Modifications (Ubl-PTMs): Small Peptides with Huge Impact in Liver Fibrosis

por Lachiondo-Ortega, Sofia, Mercado-Gómez, Maria, Serrano-Maciá, Marina, Lopitz-Otsoa, Fernando, Salas-Villalobos, Tanya B, Varela-Rey, Marta, Delgado, Teresa C., Martínez-Chantar, María Luz
Publicado 2019

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

por Juárez‐Fernández, María, Goikoetxea‐Usandizaga, Naroa, Porras, David, García‐Mediavilla, María Victoria, Bravo, Miren, Serrano‐Maciá, Marina, Simón, Jorge, Delgado, Teresa C., Lachiondo‐Ortega, Sofía, Martínez‐Flórez, Susana, Lorenzo, Óscar, Rincón, Mercedes, Varela‐Rey, Marta, Abecia, Leticia, Rodríguez, Héctor, Anguita, Juan, Nistal, Esther, Martínez‐Chantar, María Luz, Sánchez‐Campos, Sonia
Publicado 2023

Fine‐Tuning of Sirtuin 1 Expression Is Essential to Protect the Liver From Cholestatic Liver Disease

por Blokker, Britt A., Maijo, Monica, Echeandia, Marta, Galduroz, Mikel, Patterson, Angela M., Ten, Anna, Philo, Mark, Schungel, Rebecca, Gutierrez‐de Juan, Virginia, Halilbasic, Emina, Fuchs, Claudia, Le Gall, Gwenaelle, Milkiewicz, Malgorzata, Milkiewicz, Piotr, Banales, Jesus M., Rushbrook, Simon M., Mato, José M., Trauner, Michael, Müller, Michael, Martínez‐Chantar, María Luz, Varela‐Rey, Marta, Beraza, Naiara
Publicado 2019

Hepatic p63 regulates glucose metabolism by repressing SIRT1

por Gonzalez-Rellan, Maria J, Novoa, Eva, da Silva Lima, Natalia, Rodriguez, Amaia, Veyrat-Durebex, Christelle, Seoane, Samuel, Porteiro, Begoña, Fondevila, Marcos F, Fernandez, Uxia, Varela-Rey, Marta, Senra, Ana, Iglesias, Cristina, Escudero, Adriana, Fidalgo, Miguel, Guallar, Diana, Perez-Fernandez, Roman, Prevot, Vincent, Schwaninger, Markus, López, Miguel, Dieguez, Carlos, Coppari, Roberto, Frühbeck, Gema, Nogueiras, Ruben
Publicado 2023

Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves

por Gomez-Sanchez, Jose A., Carty, Lucy, Iruarrizaga-Lejarreta, Marta, Palomo-Irigoyen, Marta, Varela-Rey, Marta, Griffith, Megan, Hantke, Janina, Macias-Camara, Nuria, Azkargorta, Mikel, Aurrekoetxea, Igor, De Juan, Virginia Gutiérrez, Jefferies, Harold B.J., Aspichueta, Patricia, Elortza, Félix, Aransay, Ana M., Martínez-Chantar, María L., Baas, Frank, Mato, José M., Mirsky, Rhona, Woodhoo, Ashwin, Jessen, Kristján R.
Publicado 2015

Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer

por Barbier-Torres, Lucía, Delgado, Teresa C., García-Rodríguez, Juan L., Zubiete-Franco, Imanol, Fernández-Ramos, David, Buqué, Xabier, Cano, Ainara, Juan, Virginia Gutiérrez-de, Fernández-Domínguez, Itziar, Lopitz-Otsoa, Fernando, Fernández-Tussy, Pablo, Boix, Loreto, Bruix, Jordi, Villa, Erica, Castro, Azucena, Lu, Shelly C., Aspichueta, Patricia, Xirodimas, Dimitris, Varela-Rey, Marta, Mato, José M., Beraza, Naiara, Martínez-Chantar, María L.
Publicado 2014

A morphological method for ammonia detection in liver

por Gutiérrez-de-Juan, Virginia, López de Davalillo, Sergio, Fernández-Ramos, David, Barbier-Torres, Lucía, Zubiete-Franco, Imanol, Fernández-Tussy, Pablo, Simon, Jorge, Lopitz-Otsoa, Fernando, de las Heras, Javier, Iruzubieta, Paula, Arias-Loste, María Teresa, Villa, Erica, Crespo, Javier, Andrade, Raúl, Lucena, M. Isabel, Varela-Rey, Marta, Lu, Shelly C., Mato, José M., Delgado, Teresa Cardoso, Martínez-Chantar, María-Luz
Publicado 2017

Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function

por Gonzalez-Rellan, Maria J., Parracho, Tamara, Heras, Violeta, Rodriguez, Amaia, Fondevila, Marcos F., Novoa, Eva, Lima, Natalia, Varela-Rey, Marta, Senra, Ana, Chantada-Vazquez, Maria D.P., Ameneiro, Cristina, Bernardo, Ganeko, Fernandez-Ramos, David, Lopitz-Otsoa, Fernando, Bilbao, Jon, Guallar, Diana, Fidalgo, Miguel, Bravo, Susana, Dieguez, Carlos, Martinez-Chantar, Maria L., Millet, Oscar, Mato, Jose M., Schwaninger, Markus, Prevot, Vincent, Crespo, Javier, Frühbeck, Gema, Iruzubieta, Paula, Nogueiras, Ruben
Publicado 2023

Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation

por Barbier-Torres, Lucía, Fortner, Karen A., Iruzubieta, Paula, Delgado, Teresa C., Giddings, Emily, Chen, Youdinghuan, Champagne, Devin, Fernández-Ramos, David, Mestre, Daniela, Gomez-Santos, Beatriz, Varela-Rey, Marta, de Juan, Virginia Gutiérrez, Fernández-Tussy, Pablo, Zubiete-Franco, Imanol, García-Monzón, Carmelo, González-Rodríguez, Águeda, Oza, Dhaval, Valença-Pereira, Felipe, Fang, Qian, Crespo, Javier, Aspichueta, Patricia, Tremblay, Frederic, Christensen, Brock C., Anguita, Juan, Martínez-Chantar, María Luz, Rincón, Mercedes
Publicado 2020

MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis

por Fernández-Ramos, David, Fernández-Tussy, Pablo, Lopitz-Otsoa, Fernando, Gutiérrez-de-Juan, Virginia, Navasa, Nicolás, Barbier-Torres, Lucía, Zubiete-Franco, Imanol, Simón, Jorge, Fernández, Agustín F., Arbelaiz, Ander, Aransay, Ana M., Lavín, José Luis, Beraza, Naiara, Perugorria, María J., Banales, Jesus M., Villa, Erica, Fraga, Mario F., Anguita, Juan, Avila, Matias A., Berasain, Carmen, Iruzibieta, Paula, Crespo, Javier, Lu, Shelly C., Varela-Rey, Marta, Mato, José M., Delgado, Teresa C., Martínez-Chantar, María L.
Publicado 2018

SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer

por Zubiete-Franco, Imanol, García-Rodríguez, Juan L., Lopitz-Otsoa, Fernando, Serrano-Macia, Marina, Simon, Jorge, Fernández-Tussy, Pablo, Barbier-Torres, Lucía, Fernández-Ramos, David, Gutiérrez-de-Juan, Virginia, López de Davalillo, Sergio, Carlevaris, Onintza, Beguiristain Gómez, Adolfo, Villa, Erica, Calvisi, Diego, Martín, César, Berra, Edurne, Aspichueta, Patricia, Beraza, Naiara, Varela-Rey, Marta, Ávila, Matias, Rodríguez, Manuel S., Mato, José M., Díaz-Moreno, Irene, Díaz-Quintana, Antonio, Delgado, Teresa C., Martínez-Chantar, María L.
Publicado 2018

miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease

por Fernández-Tussy, Pablo, Fernández-Ramos, David, Lopitz-Otsoa, Fernando, Simón, Jorge, Barbier-Torres, Lucía, Gomez-Santos, Beatriz, Nuñez-Garcia, Maitane, Azkargorta, Mikel, Gutiérrez-de Juan, Virginia, Serrano-Macia, Marina, Rodríguez-Agudo, Rubén, Iruzubieta, Paula, Anguita, Juan, Castro, Rui E., Champagne, Devin, Rincón, Mercedes, Elortza, Felix, Arslanow, Anita, Krawczyk, Marcin, Lammert, Frank, Kirchmeyer, Mélanie, Behrmann, Iris, Crespo, Javier, Lu, Shelly C., Mato, José M., Varela-Rey, Marta, Aspichueta, Patricia, Delgado, Teresa C., Martínez-Chantar, María L.
Publicado 2019

Boosting mitochondria activity by silencing MCJ overcomes cholestasis-induced liver injury

por Iruzubieta, Paula, Goikoetxea-Usandizaga, Naroa, Barbier-Torres, Lucía, Serrano-Maciá, Marina, Fernández-Ramos, David, Fernández-Tussy, Pablo, Gutiérrez-de-Juan, Virginia, Lachiondo-Ortega, Sofia, Simon, Jorge, Bravo, Miren, Lopitz-Otsoa, Fernando, Robles, Mercedes, Ferre-Aracil, Carlos, Varela-Rey, Marta, Elguezabal, Natalia, Calleja, José Luis, Lu, Shelly C., Milkiewicz, Malgorzata, Milkiewicz, Piotr, Anguita, Juan, Monte, María J., Marin, José J.G., López-Hoyos, Marcos, Delgado, Teresa C., Rincón, Mercedes, Crespo, Javier, Martínez-Chantar, María Luz
Publicado 2021

The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury

por Barbier-Torres, Lucía, Iruzubieta, Paula, Fernández-Ramos, David, Delgado, Teresa C., Taibo, Daniel, Guitiérrez-de-Juan, Virginia, Varela-Rey, Marta, Azkargorta, Mikel, Navasa, Nicolas, Fernández-Tussy, Pablo, Zubiete-Franco, Imanol, Simon, Jorge, Lopitz-Otsoa, Fernando, Lachiondo-Ortega, Sofia, Crespo, Javier, Masson, Steven, McCain, Misti Vanette, Villa, Erica, Reeves, Helen, Elortza, Felix, Lucena, Maria Isabel, Hernández-Alvarez, Maria Isabel, Zorzano, Antonio, Andrade, Raúl J., Lu, Shelly C., Mato, José M., Anguita, Juan, Rincón, Mercedes, Martínez-Chantar, María Luz
Publicado 2017

Role of aramchol in steatohepatitis and fibrosis in mice

por Iruarrizaga‐Lejarreta, Marta, Varela‐Rey, Marta, Fernández‐Ramos, David, Martínez‐Arranz, Ibon, Delgado, Teresa C, Simon, Jorge, Gutiérrez‐de Juan, Virginia, delaCruz‐Villar, Laura, Azkargorta, Mikel, Lavin, José L., Mayo, Rebeca, Van Liempd, Sebastiaan M., Aurrekoetxea, Igor, Buqué, Xabier, Delle Cave, Donatella, Peña, Arantza, Rodríguez‐Cuesta, Juan, Aransay, Ana M., Elortza, Felix, Falcón‐Pérez, Juan M., Aspichueta, Patricia, Hayardeny, Liat, Noureddin, Mazen, Sanyal, Arun J., Alonso, Cristina, Anguita, Juan, Martínez‐Chantar, María Luz, Lu, Shelly C., Mato, José M.
Publicado 2017

Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis

por Sáenz de Urturi, Diego, Buqué, Xabier, Porteiro, Begoña, Folgueira, Cintia, Mora, Alfonso, Delgado, Teresa C., Prieto-Fernández, Endika, Olaizola, Paula, Gómez-Santos, Beatriz, Apodaka-Biguri, Maider, González-Romero, Francisco, Nieva-Zuluaga, Ane, Ruiz de Gauna, Mikel, Goikoetxea-Usandizaga, Naroa, García-Rodríguez, Juan Luis, Gutierrez de Juan, Virginia, Aurrekoetxea, Igor, Montalvo-Romeral, Valle, Novoa, Eva M., Martín-Guerrero, Idoia, Varela-Rey, Marta, Bhanot, Sanjay, Lee, Richard, Banales, Jesus M., Syn, Wing-Kin, Sabio, Guadalupe, Martínez-Chantar, María L., Nogueiras, Rubén, Aspichueta, Patricia
Publicado 2022

The L‐α‐Lysophosphatidylinositol/G Protein–Coupled Receptor 55 System Induces the Development of Nonalcoholic Steatosis and Steatohepatitis

por Fondevila, Marcos F., Fernandez, Uxia, Gonzalez‐Rellan, Maria J., Da Silva Lima, Natalia, Buque, Xabier, Gonzalez‐Rodriguez, Agueda, Alonso, Cristina, Iruarrizaga‐Lejarreta, Marta, Delgado, Teresa C., Varela‐Rey, Marta, Senra, Ana, Garcia‐Outeiral, Vera, Novoa, Eva, Iglesias, Cristina, Porteiro, Begoña, Beiroa, Daniel, Folgueira, Cintia, Tojo, Marta, Torres, Jorge L., Hernández‐Cosido, Lourdes, Blanco, Óscar, Arab, Juan Pablo, Barrera, Francisco, Guallar, Diana, Fidalgo, Miguel, López, Miguel, Dieguez, Carlos, Marcos, Miguel, Martinez‐Chantar, Maria L., Arrese, Marco, Garcia‐Monzon, Carmelo, Mato, Jose M., Aspichueta, Patricia, Nogueiras, Ruben
Publicado 2020

Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH

por Simón, Jorge, Goikoetxea-Usandizaga, Naroa, Serrano-Maciá, Marina, Fernández-Ramos, David, Sáenz de Urturi, Diego, Gruskos, Jessica J., Fernández-Tussy, Pablo, Lachiondo-Ortega, Sofía, González-Recio, Irene, Rodríguez-Agudo, Rubén, Gutiérrez-de-Juan, Virginia, Rodríguez-Iruretagoyena, Begoña, Varela-Rey, Marta, Gimenez-Mascarell, Paula, Mercado-Gomez, María, Gómez-Santos, Beatriz, Fernandez-Rodriguez, Carmen, Lopitz-Otsoa, Fernando, Bizkarguenaga, Maider, Dames, Sibylle, Schaeper, Ute, Martin, Franz, Sabio, Guadalupe, Iruzubieta, Paula, Crespo, Javier, Aspichueta, Patricia, Chu, Kevan H.-Y., Buccella, Daniela, Martín, César, Delgado, Teresa Cardoso, Martínez-Cruz, Luis Alfonso, Martínez-Chantar, María Luz
Publicado 2021

Mitochondrial bioenergetics boost macrophage activation, promoting liver regeneration in metabolically compromised animals

por Goikoetxea‐Usandizaga, Naroa, Serrano‐Maciá, Marina, Delgado, Teresa C., Simón, Jorge, Fernández Ramos, David, Barriales, Diego, Cornide, Maria E., Jiménez, Mónica, Pérez‐Redondo, Marina, Lachiondo‐Ortega, Sofia, Rodríguez‐Agudo, Rubén, Bizkarguenaga, Maider, Zalamea, Juan Diego, Pasco, Samuel T., Caballero‐Díaz, Daniel, Alfano, Benedetta, Bravo, Miren, González‐Recio, Irene, Mercado‐Gómez, Maria, Gil‐Pitarch, Clàudia, Mabe, Jon, Gracia‐Sancho, Jordi, Abecia, Leticia, Lorenzo, Óscar, Martín‐Sanz, Paloma, Abrescia, Nicola G. A., Sabio, Guadalupe, Rincón, Mercedes, Anguita, Juan, Miñambres, Eduardo, Martín, César, Berenguer, Marina, Fabregat, Isabel, Casado, Marta, Peralta, Carmen, Varela‐Rey, Marta, Martínez‐Chantar, María Luz
Publicado 2021