Differential vulnerability of hippocampal CA3-CA1 synapses to Aβ

por Shipton, Olivia A., Tang, Clara S., Paulsen, Ole, Vargas-Caballero, Mariana
Publicado 2022

Vagus Nerve Stimulation as a Potential Therapy in Early Alzheimer’s Disease: A Review

por Vargas-Caballero, Mariana, Warming, Hannah, Walker, Robert, Holmes, Clive, Cruickshank, Garth, Patel, Bipin
Publicado 2022

α5 Subunit-containing GABA(A) receptors mediate a slowly decaying inhibitory synaptic current in CA1 pyramidal neurons following Schaffer collateral activation

por Vargas-Caballero, Mariana, Martin, Loren J., Salter, Michael W., Orser, Beverley A., Paulsen, Ole
Publicado 2010

Stochastic and deterministic dynamics of intrinsically irregular firing in cortical inhibitory interneurons

por Mendonça, Philipe RF, Vargas-Caballero, Mariana, Erdélyi, Ferenc, Szabó, Gábor, Paulsen, Ole, Robinson, Hugh PC
Publicado 2016

A luminescence-based reporter to study tau secretion reveals overlapping mechanisms for the release of healthy and pathological tau

por Lopez, Dianne Marquez, Maltby, Connor J., Warming, Hannah, Divecha, Nullin, Vargas-Caballero, Mariana, Coldwell, Mark J., Deinhardt, Katrin
Publicado 2023

A 5′ UTR GGN repeat controls localisation and translation of a potassium leak channel mRNA through G-quadruplex formation

por Maltby, Connor J, Schofield, James P R, Houghton, Steven D, O’Kelly, Ita, Vargas-Caballero, Mariana, Deinhardt, Katrin, Coldwell, Mark J
Publicado 2020

Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology

por Olmos-Alonso, Adrian, Schetters, Sjoerd T. T., Sri, Sarmi, Askew, Katharine, Mancuso, Renzo, Vargas-Caballero, Mariana, Holscher, Christian, Perry, V. Hugh, Gomez-Nicola, Diego
Publicado 2016

Tau-proximity ligation assay reveals extensive previously undetected pathology prior to neurofibrillary tangles in preclinical Alzheimer’s disease

por Bengoa-Vergniory, Nora, Velentza-Almpani, Elisavet, Silva, Ana Maria, Scott, Connor, Vargas-Caballero, Mariana, Sastre, Magdalena, Wade-Martins, Richard, Alegre-Abarrategui, Javier
Publicado 2021

Elevated amyloid beta disrupts the nanoscale organization and function of synaptic vesicle pools in hippocampal neurons

por Biasetti, Luca, Rey, Stephanie, Fowler, Milena, Ratnayaka, Arjuna, Fennell, Kate, Smith, Catherine, Marshall, Karen, Hall, Catherine, Vargas-Caballero, Mariana, Serpell, Louise, Staras, Kevin
Publicado 2022

Wild-Type, but Not Mutant N296H, Human Tau Restores Aβ-Mediated Inhibition of LTP in Tau(−/−) mice

por Vargas-Caballero, Mariana, Denk, Franziska, Wobst, Heike J., Arch, Emily, Pegasiou, Chrysia-Maria, Oliver, Peter L., Shipton, Olivia A., Paulsen, Ole, Wade-Martins, Richard
Publicado 2017

Emergence of synaptic and cognitive impairment in a mature-onset APP mouse model of Alzheimer’s disease

por Sri, Sarmi, Pegasiou, Chrysia-Maria, Cave, Chantal Abbigail, Hough, Katie, Wood, Natalie, Gomez-Nicola, Diego, Deinhardt, Katrin, Bannerman, David, Perry, V. Hugh, Vargas-Caballero, Mariana
Publicado 2019

Temporal dynamics of hippocampal neurogenesis in chronic neurodegeneration

por Gomez-Nicola, Diego, Suzzi, Stefano, Vargas-Caballero, Mariana, Fransen, Nina L., Al-Malki, Hussain, Cebrian-Silla, Arantxa, Garcia-Verdugo, Jose Manuel, Riecken, Kristoffer, Fehse, Boris, Perry, V. Hugh
Publicado 2014

A primate-specific short GluN2A-NMDA receptor isoform is expressed in the human brain

por Warming, Hannah, Pegasiou, Chrysia-Maria, Pitera, Aleksandra P., Kariis, Hanna, Houghton, Steven D., Kurbatskaya, Ksenia, Ahmed, Aminul, Grundy, Paul, Vajramani, Girish, Bulters, Diederik, Altafaj, Xavier, Deinhardt, Katrin, Vargas-Caballero, Mariana
Publicado 2019

Age-related changes in tau and autophagy in human brain in the absence of neurodegeneration

por Chatterjee, Shreyasi, Sealey, Megan, Ruiz, Eva, Pegasiou, Chrysia M., Brookes, Keeley, Green, Sam, Crisford, Anna, Duque-Vasquez, Michael, Luckett, Emma, Robertson, Rebecca, Richardson, Philippa, Vajramani, Girish, Grundy, Paul, Bulters, Diederik, Proud, Christopher, Vargas-Caballero, Mariana, Mudher, Amritpal
Publicado 2023