The Phe-Phe Motif for Peptide Self-Assembly in Nanomedicine

por Marchesan, Silvia, Vargiu, Attilio V., Styan, Katie E.
Publicado 2015

Computational Study of Correlated Domain Motions in the AcrB Efflux Transporter

por Schulz, Robert, Vargiu, Attilio V., Ruggerone, Paolo, Kleinekathöfer, Ulrich
Publicado 2015

Editorial: Bad Bugs in the XXIst Century: Resistance Mediated by Multi-Drug Efflux Pumps in Gram-Negative Bacteria

por Vargiu, Attilio V., Pos, Klaas M., Poole, Keith, Nikaido, Hiroshi
Publicado 2016

Functional Rotation of the Transporter AcrB: Insights into Drug Extrusion from Simulations

por Schulz, Robert, Vargiu, Attilio V., Collu, Francesca, Kleinekathöfer, Ulrich, Ruggerone, Paolo
Publicado 2010

Molecular Dynamics Computer Simulations of Multidrug RND Efflux Pumps

por Ruggerone, Paolo, Vargiu, Attilio V., Collu, Francesca, Fischer, Nadine, Kandt, Christian
Publicado 2013

Molecular Rationale behind the Differential Substrate Specificity of Bacterial RND Multi-Drug Transporters

por Ramaswamy, Venkata Krishnan, Vargiu, Attilio V., Malloci, Giuliano, Dreier, Jürg, Ruggerone, Paolo
Publicado 2017

Molecular Determinants of the Promiscuity of MexB and MexY Multidrug Transporters of Pseudomonas aeruginosa

por Ramaswamy, Venkata K., Vargiu, Attilio V., Malloci, Giuliano, Dreier, Jürg, Ruggerone, Paolo
Publicado 2018

AB-DB: Force-Field parameters, MD trajectories, QM-based data, and Descriptors of Antimicrobials

por Gervasoni, Silvia, Malloci, Giuliano, Bosin, Andrea, Vargiu, Attilio V., Zgurskaya, Helen I., Ruggerone, Paolo
Publicado 2022

Recognition of quinolone antibiotics by the multidrug efflux transporter MexB of Pseudomonas aeruginosa

por Gervasoni, Silvia, Malloci, Giuliano, Bosin, Andrea, Vargiu, Attilio V., Zgurskaya, Helen I., Ruggerone, Paolo
Publicado 2022

Molecular rationale for the impairment of the MexAB-OprM efflux pump by a single mutation in MexA

por Cacciotto, Pierpaolo, Basciu, Andrea, Oliva, Francesco, Malloci, Giuliano, Zacharias, Martin, Ruggerone, Paolo, Vargiu, Attilio V.
Publicado 2021

Molecular Insights Into Binding and Activation of the Human KCNQ2 Channel by Retigabine

por Garofalo, Barbara, Bonvin, Alexandre M.J.J., Bosin, Andrea, Di Giorgio, Francesco P., Ombrato, Rosella, Vargiu, Attilio V.
Publicado 2022

Relevance of Ebola virus VP35 homo-dimerization on the type I interferon cascade inhibition

por Di Palma, Francesco, Daino, Gian Luca, Ramaswamy, Venkata Krishnan, Corona, Angela, Frau, Aldo, Fanunza, Elisa, Vargiu, Attilio V, Tramontano, Enzo, Ruggerone, Paolo
Publicado 2019

Structural and functional analysis of the promiscuous AcrB and AdeB efflux pumps suggests different drug binding mechanisms

por Ornik-Cha, Alina, Wilhelm, Julia, Kobylka, Jessica, Sjuts, Hanno, Vargiu, Attilio V., Malloci, Giuliano, Reitz, Julian, Seybert, Anja, Frangakis, Achilleas S., Pos, Klaas M.
Publicado 2021

Nanoscale Assembly of Functional Peptides with Divergent Programming Elements

por Garcia, Ana M., Melchionna, Michele, Bellotto, Ottavia, Kralj, Slavko, Semeraro, Sabrina, Parisi, Evelina, Iglesias, Daniel, D’Andrea, Paola, De Zorzi, Rita, Vargiu, Attilio V., Marchesan, Silvia
Publicado 2021

Heterochirality and Halogenation Control Phe-Phe Hierarchical Assembly

por Kralj, Slavko, Bellotto, Ottavia, Parisi, Evelina, Garcia, Ana M., Iglesias, Daniel, Semeraro, Sabrina, Deganutti, Caterina, D’Andrea, Paola, Vargiu, Attilio V., Geremia, Silvano, De Zorzi, Rita, Marchesan, Silvia
Publicado 2020

Molecular determinants of avoidance and inhibition of Pseudomonas aeruginosa MexB efflux pump

por Gervasoni, Silvia, Mehla, Jitender, Bergen, Charles R., Leus, Inga V., Margiotta, Enrico, Malloci, Giuliano, Bosin, Andrea, Vargiu, Attilio V., Lomovskaya, Olga, Rybenkov, Valentin V., Ruggerone, Paolo, Zgurskaya, Helen I.
Publicado 2023

Chlorpromazine and Amitriptyline Are Substrates and Inhibitors of the AcrB Multidrug Efflux Pump

por Grimsey, Elizabeth M., Fais, Chiara, Marshall, Robert L., Ricci, Vito, Ciusa, Maria Laura, Stone, Jack W., Ivens, Alasdair, Malloci, Giuliano, Ruggerone, Paolo, Vargiu, Attilio V., Piddock, Laura J. V.
Publicado 2020

Cryo-EM Structure and Molecular Dynamics Analysis of the Fluoroquinolone Resistant Mutant of the AcrB Transporter from Salmonella

por Johnson, Rachel M., Fais, Chiara, Parmar, Mayuriben, Cheruvara, Harish, Marshall, Robert L., Hesketh, Sophie J., Feasey, Matthew C., Ruggerone, Paolo, Vargiu, Attilio V., Postis, Vincent L. G., Muench, Stephen P., Bavro, Vassiliy N.
Publicado 2020

Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB

por Reading, Eamonn, Ahdash, Zainab, Fais, Chiara, Ricci, Vito, Wang-Kan, Xuan, Grimsey, Elizabeth, Stone, Jack, Malloci, Giuliano, Lau, Andy M., Findlay, Heather, Konijnenberg, Albert, Booth, Paula J., Ruggerone, Paolo, Vargiu, Attilio V., Piddock, Laura J. V., Politis, Argyris
Publicado 2020

Predictive Rules of Efflux Inhibition and Avoidance in Pseudomonas aeruginosa

por Mehla, Jitender, Malloci, Giuliano, Mansbach, Rachael, López, Cesar A., Tsivkovski, Ruslan, Haynes, Keith, Leus, Inga V., Grindstaff, Sally B., Cascella, Robert H., D’Cunha, Napoleon, Herndon, Liam, Hengartner, Nicolas W., Margiotta, Enrico, Atzori, Alessio, Vargiu, Attilio V., Manrique, Pedro D., Walker, John K., Lomovskaya, Olga, Ruggerone, Paolo, Gnanakaran, S., Rybenkov, Valentin V., Zgurskaya, Helen I.
Publicado 2021