Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas

por Varnat, Frédéric, Siegl-Cachedenier, Irene, Malerba, Monica, Gervaz, Pascal, Ruiz i Altaba, Ariel
Publicado 2010

Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

por Varnat, Frédéric, Duquet, Arnaud, Malerba, Monica, Zbinden, Marie, Mas, Christophe, Gervaz, Pascal, Ruiz i Altaba, Ariel
Publicado 2009