Computationally Derived Points of Fragility of a Human Cascade Are Consistent with Current Therapeutic Strategies

por Luan, Deyan, Zai, Michael, Varner, Jeffrey D
Publicado 2007

Analysis of the role of thrombomodulin in all-trans retinoic acid treatment of coagulation disorders in cancer patients

por Ghaffari, Hamed, Varner, Jeffrey D., Petzold, Linda R.
Publicado 2019

Computational Modeling and Analysis of Insulin Induced Eukaryotic Translation Initiation

por Lequieu, Joshua, Chakrabarti, Anirikh, Nayak, Satyaprakash, Varner, Jeffrey D.
Publicado 2011

A Test of Highly Optimized Tolerance Reveals Fragile Cell-Cycle Mechanisms Are Molecular Targets in Clinical Cancer Trials

por Nayak, Satyaprakash, Salim, Saniya, Luan, Deyan, Zai, Michael, Varner, Jeffrey D.
Publicado 2008

Population Heterogeneity in the Epithelial to Mesenchymal Transition Is Controlled by NFAT and Phosphorylated Sp1

por Gould, Russell, Bassen, David M., Chakrabarti, Anirikh, Varner, Jeffrey D., Butcher, Jonathan
Publicado 2016

JuPOETs: a constrained multiobjective optimization approach to estimate biochemical model ensembles in the Julia programming language

por Bassen, David M., Vilkhovoy, Michael, Minot, Mason, Butcher, Jonathan T., Varner, Jeffrey D.
Publicado 2017

Reduced order modeling and analysis of the human complement system

por Sagar, Adithya, Dai, Wei, Minot, Mason, LeCover, Rachel, Varner, Jeffrey D.
Publicado 2017

Multi-scale computational study of the Warburg effect, reverse Warburg effect and glutamine addiction in solid tumors

por Shan, Mengrou, Dai, David, Vudem, Arunodai, Varner, Jeffrey D., Stroock, Abraham D.
Publicado 2018

Effective Biophysical Modeling of Cell Free Transcription and Translation Processes

por Adhikari, Abhinav, Vilkhovoy, Michael, Vadhin, Sandra, Lim, Ha Eun, Varner, Jeffrey D.
Publicado 2020

Analysis of the Molecular Networks in Androgen Dependent and Independent Prostate Cancer Revealed Fragile and Robust Subsystems

por Tasseff, Ryan, Nayak, Satyaprakash, Salim, Saniya, Kaushik, Poorvi, Rizvi, Noreen, Varner, Jeffrey D.
Publicado 2010

Induced myelomonocytic differentiation in leukemia cells is accompanied by noncanonical transcription factor expression

por Jensen, Holly A., Yourish, Harmony B., Bunaciu, Rodica P., Varner, Jeffrey D., Yen, Andrew
Publicado 2015

Toward a genome scale sequence specific dynamic model of cell-free protein synthesis in Escherichia coli

por Horvath, Nicholas, Vilkhovoy, Michael, Wayman, Joseph A., Calhoun, Kara, Swartz, James, Varner, Jeffrey D.
Publicado 2019

Differential Contributions of Intrinsic and Extrinsic Pathways to Thrombin Generation in Adult, Maternal and Cord Plasma Samples

por Rice, Nicklaus T., Szlam, Fania, Varner, Jeffrey D., Bernstein, Peter S., Szlam, Arthur D., Tanaka, Kenichi A.
Publicado 2016

Improving designer glycan production in Escherichia coli through model-guided metabolic engineering

por Wayman, Joseph A., Glasscock, Cameron, Mansell, Thomas J., DeLisa, Matthew P., Varner, Jeffrey D.
Publicado 2019

Retinoic Acid Therapy Resistance Progresses from Unilineage to Bilineage in HL-60 Leukemic Blasts

por Jensen, Holly A., Bunaciu, Rodica P., Ibabao, Christopher N., Myers, Rebecca, Varner, Jeffrey D., Yen, Andrew
Publicado 2014

The Src-Family Kinase Inhibitor PP2 Rescues Inducible Differentiation Events in Emergent Retinoic Acid-Resistant Myeloblastic Leukemia Cells

por Jensen, Holly A., Styskal, Lauren E., Tasseff, Ryan, Bunaciu, Rodica P., Congleton, Johanna, Varner, Jeffrey D., Yen, Andrew
Publicado 2013

6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells

por Bunaciu, Rodica P., Jensen, Holly A., MacDonald, Robert J., LaTocha, Dorian H., Varner, Jeffrey D., Yen, Andrew
Publicado 2015

An Effective Model of the Retinoic Acid Induced HL-60 Differentiation Program

por Tasseff, Ryan, Jensen, Holly A., Congleton, Johanna, Dai, David, Rogers, Katharine V., Sagar, Adithya, Bunaciu, Rodica P., Yen, Andrew, Varner, Jeffrey D.
Publicado 2017

Potential for subsets of wt-NPM1 primary AML blasts to respond to retinoic acid treatment

por Bunaciu, Rodica P., MacDonald, Robert J., Gao, Feng, Johnson, Lynn M., Varner, Jeffrey D., Wang, Xin, Nataraj, Sarah, Guzman, Monica L., Yen, Andrew
Publicado 2017

Endothelial cells metabolically regulate breast cancer invasion toward a microvessel

por Tan, Matthew L., Jenkins-Johnston, Niaa, Huang, Sarah, Schutrum, Brittany, Vadhin, Sandra, Adhikari, Abhinav, Williams, Rebecca M., Zipfel, Warren R., Lammerding, Jan, Varner, Jeffrey D., Fischbach, Claudia
Publicado 2023