LGR4 and Its Extracellular Domain as Novel Regulators of ß-Cell Survival and Proliferation

por Filipowska, Joanna K, Kondegowda, Nagesha G, Vasavada, Rupangi C
Publicado 2021

The Retinoblastoma Protein and Its Homolog p130 Regulate the G(1)/S Transition in Pancreatic β-Cells

por Harb, George, Vasavada, Rupangi C., Cobrinik, David, Stewart, Andrew F.
Publicado 2009

LGR4, a G Protein-Coupled Receptor With a Systemic Role: From Development to Metabolic Regulation

por Filipowska, Joanna, Kondegowda, Nagesha G., Leon-Rivera, Nancy, Dhawan, Sangeeta, Vasavada, Rupangi C.
Publicado 2022

Gestational Diabetes Mellitus Resulting From Impaired β-Cell Compensation in the Absence of FoxM1, a Novel Downstream Effector of Placental Lactogen

por Zhang, Hongjie, Zhang, Jia, Pope, Christine F., Crawford, Laura A., Vasavada, Rupangi C., Jagasia, Shubhada M., Gannon, Maureen
Publicado 2010

Human β-Cell Proliferation and Intracellular Signaling: Part 3

por Stewart, Andrew F., Hussain, Mehboob A., García-Ocaña, Adolfo, Vasavada, Rupangi C., Bhushan, Anil, Bernal-Mizrachi, Ernesto, Kulkarni, Rohit N.
Publicado 2015

Hepatocyte Growth Factor/c-Met Signaling Is Required for β-Cell Regeneration

por Alvarez-Perez, Juan Carlos, Ernst, Sara, Demirci, Cem, Casinelli, Gabriella P., Mellado-Gil, Jose Manuel D., Rausell-Palamos, Francisco, Vasavada, Rupangi C., Garcia-Ocaña, Adolfo
Publicado 2014

Loss of HGF/c-Met Signaling in Pancreatic β-Cells Leads to Incomplete Maternal β-Cell Adaptation and Gestational Diabetes Mellitus

por Demirci, Cem, Ernst, Sara, Alvarez-Perez, Juan C., Rosa, Taylor, Valle, Shelley, Shridhar, Varsha, Casinelli, Gabriella P., Alonso, Laura C., Vasavada, Rupangi C., García-Ocana, Adolfo
Publicado 2012

RANKL/RANK is required for cytokine-induced beta cell death; osteoprotegerin, a RANKL inhibitor, reverses rodent type 1 diabetes

por Kondegowda, Nagesha Guthalu, Filipowska, Joanna, Do, Jeong-su, Leon-Rivera, Nancy, Li, Rosemary, Hampton, Rollie, Ogyaadu, Selassie, Levister, Camilla, Penninger, Josef M., Reijonen, Helena, Levy, Carol J., Vasavada, Rupangi C.
Publicado 2023

Parathyroid Hormone–Related Protein Enhances Human β-Cell Proliferation and Function With Associated Induction of Cyclin-Dependent Kinase 2 and Cyclin E Expression

por Guthalu Kondegowda, Nagesha, Joshi-Gokhale, Sheela, Harb, George, Williams, Katoura, Zhang, Xiao Ying, Takane, Karen K., Zhang, Pili, Scott, Donald K., Stewart, Andrew F., Garcia-Ocaña, Adolfo, Vasavada, Rupangi C.
Publicado 2010

Disruption of Hepatocyte Growth Factor/c-Met Signaling Enhances Pancreatic β-Cell Death and Accelerates the Onset of Diabetes

por Mellado-Gil, Jose, Rosa, Taylor C., Demirci, Cem, Gonzalez-Pertusa, Jose A., Velazquez-Garcia, Silvia, Ernst, Sara, Valle, Shelley, Vasavada, Rupangi C., Stewart, Andrew F., Alonso, Laura C., Garcia-Ocaña, Adolfo
Publicado 2011

PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2

por Lakshmipathi, Jayalakshmi, Alvarez-Perez, Juan Carlos, Rosselot, Carolina, Casinelli, Gabriella P., Stamateris, Rachel E., Rausell-Palamos, Francisco, O’Donnell, Christopher P., Vasavada, Rupangi C., Scott, Donald K., Alonso, Laura C., Garcia-Ocaña, Adolfo
Publicado 2016

Activation of Protein Kinase C-ζ in Pancreatic β-Cells In Vivo Improves Glucose Tolerance and Induces β-Cell Expansion via mTOR Activation

por Velazquez-Garcia, Silvia, Valle, Shelley, Rosa, Taylor C., Takane, Karen K., Demirci, Cem, Alvarez-Perez, Juan C., Mellado-Gil, Jose M., Ernst, Sara, Scott, Donald K., Vasavada, Rupangi C., Alonso, Laura C., Garcia-Ocaña, Adolfo
Publicado 2011

ChREBP Mediates Glucose-Stimulated Pancreatic β-Cell Proliferation

por Metukuri, Mallikarjuna R., Zhang, Pili, Basantani, Mahesh K., Chin, Connie, Stamateris, Rachel E., Alonso, Laura C., Takane, Karen K., Gramignoli, Roberto, Strom, Stephen C., O’Doherty, Robert M., Stewart, Andrew F., Vasavada, Rupangi C., Garcia-Ocaña, Adolfo, Scott, Donald K.
Publicado 2012