The finger loop of the SRA domain in the E3 ligase UHRF1 is a regulator of ubiquitin targeting and is required for the maintenance of DNA methylation

por Vaughan, Robert M., Rothbart, Scott B., Dickson, Bradley M.
Publicado 2019

Analysis of histone antibody specificity directly in sequencing data using siQ-ChIP

por Kupai, Ariana, Vaughan, Robert M., Rothbart, Scott B., Dickson, Bradley M.
Publicado 2023

Streamlined quantitative analysis of histone modification abundance at nucleosome-scale resolution with siQ-ChIP version 2.0

por Dickson, Bradley M., Kupai, Ariana, Vaughan, Robert M., Rothbart, Scott B.
Publicado 2023

A Degenerate Peptide Library Approach to Reveal Sequence Determinants of Methyllysine-Driven Protein Interactions

por Kupai, Ariana, Vaughan, Robert M., Dickson, Bradley M., Rothbart, Scott B.
Publicado 2020

Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance

por Vaughan, Robert M, Dickson, Bradley M, Cornett, Evan M, Harrison, Joseph S, Kuhlman, Brian, Rothbart, Scott B
Publicado 2018

A physical basis for quantitative ChIP-sequencing

por Dickson, Bradley M., Tiedemann, Rochelle L., Chomiak, Alison A., Cornett, Evan M., Vaughan, Robert M., Rothbart, Scott B.
Publicado 2020

Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1

por Vaughan, Robert M., Dickson, Bradley M., Whelihan, Matthew F., Johnstone, Andrea L., Cornett, Evan M., Cheek, Marcus A., Ausherman, Christine A., Cowles, Martis W., Sun, Zu-Wen, Rothbart, Scott B.
Publicado 2018

A Read/Write Mechanism Connects p300 Bromodomain Function to H2A.Z Acetylation

por Colino-Sanguino, Yolanda, Cornett, Evan M., Moulder, David, Smith, Grady C., Hrit, Joel, Cordeiro-Spinetti, Eric, Vaughan, Robert M., Krajewski, Krzysztof, Rothbart, Scott B., Clark, Susan J., Valdés-Mora, Fátima
Publicado 2019

Chemical Biology Screening Identifies a Vulnerability to Checkpoint Kinase Inhibitors in TSC2-Deficient Renal Angiomyolipomas

por Vaughan, Robert M., Kordich, Jennifer J., Chan, Chun-Yuan, Sasi, Nanda K., Celano, Stephanie L., Sisson, Kellie A., Van Baren, Megan, Kortus, Matthew G., Aguiar, Dean J., Martin, Katie R., MacKeigan, Jeffrey P.
Publicado 2022

The complex, dynamic SpliceOme of the small GTPase transcripts altered by technique, sex, genetics, tissue specificity, and RNA base editing

por Das, Akansha S., Sherry, Emily C., Vaughan, Robert M., Henderson, Marian L., Zieba, Jacob, Uhl, Katie L., Koehn, Olivia, Bupp, Caleb P., Rajasekaran, Surender, Li, Xiaopeng, Chhetri, Surya B., Nissim, Sahar, Williams, Carol L., Prokop, Jeremy W.
Publicado 2022

A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity

por Cornett, Evan M., Dickson, Bradley M., Krajewski, Krzysztof, Spellmon, Nicholas, Umstead, Andrew, Vaughan, Robert M., Shaw, Kevin M., Versluis, Philip P., Cowles, Martis W., Brunzelle, Joseph, Yang, Zhe, Vega, Irving E., Sun, Zu-Wen, Rothbart, Scott B.
Publicado 2018

A trivalent nucleosome interaction by PHIP/BRWD2 is disrupted in neurodevelopmental disorders and cancer

por Morgan, Marc A.J., Popova, Irina K., Vaidya, Anup, Burg, Jonathan M., Marunde, Matthew R., Rendleman, Emily J., Dumar, Zachary J., Watson, Rachel, Meiners, Matthew J., Howard, Sarah A., Khalatyan, Natalia, Vaughan, Robert M., Rothbart, Scott B., Keogh, Michael-C., Shilatifard, Ali
Publicado 2021

The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cel...

por Vaughan, Robert M., Kupai, Ariana, Foley, Caroline A., Sagum, Cari A., Tibben, Bailey M., Eden, Hope E., Tiedemann, Rochelle L., Berryhill, Christine A., Patel, Varun, Shaw, Kevin M., Krajewski, Krzysztof, Strahl, Brian D., Bedford, Mark T., Frye, Stephen V., Dickson, Bradley M., Rothbart, Scott B.
Publicado 2020