Stoichiometry of ubiquitin-binding proteins directs DSB repair

por Bakkenist, Christopher J, Vaziri, Cyrus
Publicado 2013

A non-catalytic role of DNA polymerase η in recruiting Rad18 and promoting PCNA monoubiquitination at stalled replication forks

por Durando, Michael, Tateishi, Satoshi, Vaziri, Cyrus
Publicado 2013

Mechanisms of Post-Replication DNA Repair

por Gao, Yanzhe, Mutter-Rottmayer, Elizabeth, Zlatanou, Anastasia, Vaziri, Cyrus, Yang, Yang
Publicado 2017

Unravelling roles of error-prone DNA polymerases in shaping cancer genomes

por Vaziri, Cyrus, Rogozin, Igor B., Gu, Qisheng, Wu, Di, Day, Tovah A.
Publicado 2021

Diverse roles of RAD18 and Y-family DNA polymerases in tumorigenesis

por Yang, Yang, Gao, Yanzhe, Zlatanou, Anastasia, Tateishi, Satoshi, Yurchenko, Vyacheslav, Rogozin, Igor B., Vaziri, Cyrus
Publicado 2018

Roles of trans-lesion synthesis (TLS) DNA polymerases in tumorigenesis and cancer therapy

por Anand, Jay, Chiou, Lilly, Sciandra, Carly, Zhang, Xingyuan, Hong, Jiyong, Wu, Di, Zhou, Pei, Vaziri, Cyrus
Publicado 2023

Phosphorylated Rad18 directs DNA Polymerase η to sites of stalled replication

por Day, Tovah A., Palle, Komariah, Barkley, Laura R., Kakusho, Naoko, Zou, Ying, Tateishi, Satoshi, Verreault, Alain, Masai, Hisao, Vaziri, Cyrus
Publicado 2010

c-Jun N-terminal kinase–mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forks

por Barkley, Laura R., Palle, Komaraiah, Durando, Michael, Day, Tovah A., Gurkar, Aditi, Kakusho, Naoko, Li, Jianying, Masai, Hisao, Vaziri, Cyrus
Publicado 2012

Cell cycle stage-specific roles of Rad18 in tolerance and repair of oxidative DNA damage

por Yang, Yang, Durando, Michael, Smith-Roe, Stephanie L., Sproul, Chris, Greenwalt, Alicia M., Kaufmann, William, Oh, Sehyun, Hendrickson, Eric A., Vaziri, Cyrus
Publicado 2013

The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells

por Gao, Yanzhe, Kardos, Jordan, Yang, Yang, Tamir, Tigist Y., Mutter-Rottmayer, Elizabeth, Weissman, Bernard, Major, Michael B., Kim, William Y., Vaziri, Cyrus
Publicado 2018

DNA repair factor RAD18 and DNA polymerase Polκ confer tolerance of oncogenic DNA replication stress

por Yang, Yang, Gao, Yanzhe, Mutter-Rottmayer, Liz, Zlatanou, Anastasia, Durando, Michael, Ding, Weimin, Wyatt, David, Ramsden, Dale, Tanoue, Yuki, Tateishi, Satoshi, Vaziri, Cyrus
Publicado 2017

VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in KRAS-mutant pancreatic cancer

por Lee, Ye S., Klomp, Jennifer E., Stalnecker, Clint A., Goodwin, Craig M., Gao, Yanzhe, Droby, Gaith N., Vaziri, Cyrus, Bryant, Kirsten L., Der, Channing J., Cox, Adrienne D.
Publicado 2023

The TRIM69-MST2 signaling axis regulates centrosome dynamics and chromosome segregation

por Wang, Yilin, Risteski, Patrik, Yang, Yang, Chen, Huan, Droby, Gaith, Walens, Andrea, Jayaprakash, Deepika, Troester, Melissa, Herring, Laura, Chernoff, Jonathan, Tolić, Iva M, Bowser, Jessica, Vaziri, Cyrus
Publicado 2023

Rad18 confers hematopoietic progenitor cell DNA damage tolerance independently of the Fanconi Anemia pathway in vivo

por Yang, Yang, Poe, Jonathan C., Yang, Lisong, Fedoriw, Andrew, Desai, Siddhi, Magnuson, Terry, Li, Zhiguo, Fedoriw, Yuri, Araki, Kimi, Gao, Yanzhe, Tateishi, Satoshi, Sarantopoulos, Stefanie, Vaziri, Cyrus
Publicado 2016

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis

por Gao, Yanzhe, Mutter-Rottmayer, Elizabeth, Greenwalt, Alicia M., Goldfarb, Dennis, Yan, Feng, Yang, Yang, Martinez-Chacin, Raquel C., Pearce, Kenneth H., Tateishi, Satoshi, Major, Michael B., Vaziri, Cyrus
Publicado 2016

Rad18 mediates specific mutational signatures and shapes the genomic landscape of carcinogen-induced tumors in vivo

por Lou, Jitong, Yang, Yang, Gu, Qisheng, Price, Brandon A, Qiu, Yuheng, Fedoriw, Yuri, Desai, Siddhi, Mose, Lisle E, Chen, Brian, Tateishi, Satoshi, Parker, Joel S, Vaziri, Cyrus, Wu, Di
Publicado 2021

Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxifen-resistant breast cancer cells

por Liang, Zheyong, Li, Wenjie, Liu, Jie, Li, Juan, He, Fang, Jiang, Yina, Yang, Lu, Li, Pingping, Wang, Bo, Wang, Yaochun, Ren, Yu, Yang, Jin, Luo, Zhijun, Vaziri, Cyrus, Liu, Peijun
Publicado 2017

Simvastatin and Atorvastatin inhibit DNA replication licensing factor MCM7 and effectively suppress RB-deficient tumors growth

por Li, Juan, Liu, Jie, Liang, Zheyong, He, Fang, Yang, Lu, Li, Pingping, Jiang, Yina, Wang, Bo, Zhou, Can, Wang, Yaochun, Ren, Yu, Yang, Jin, Zhang, Jianmin, Luo, Zhijun, Vaziri, Cyrus, Liu, Peijun
Publicado 2017

RNA-Based Classification of Homologous Recombination Deficiency in Racially Diverse Patients with Breast Cancer

por Walens, Andrea, Van Alsten, Sarah C., Olsson, Linnea T., Smith, Markia A., Lockhart, Alex, Gao, Xiaohua, Hamilton, Alina M., Kirk, Erin L., Love, Michael I., Gupta, Gaorav P., Perou, Charles M., Vaziri, Cyrus, Hoadley, Katherine A., Troester, Melissa A.
Publicado 2022

Trans-Lesion Synthesis and Mismatch Repair Pathway Crosstalk Defines Chemoresistance and Hypermutation Mechanisms in Glioblastoma

por Cheng, Xing, An, Jing, Lou, Jitong, Gu, Qisheng, Ding, Weimin, Droby, Gaith, Wang, Yilin, Wang, Chenghao, Gao, Yanzhe, Shelton, Abigail, Satterlee, Andrew Benson, Mann, Breanna Elizabeth, Hsiao, Yun-Chung, Liu, Chih-Wei, Liu, Kun, Hingtgen, Shawn, Wang, Jiguang, Liu, Zhaoliang, Miller, Ryan, Wu, Di, Vaziri, Cyrus, Yang, Yang
Publicado 2023