Discovery of Nedd4 auto-ubiquitination inhibitors

por Yong, Darren, Green, Stuart R., Ghiabi, Pegah, Santhakumar, Vijayaratnam, Vedadi, Masoud
Publicado 2023

Identification of 2,4-diamino-6,7-dimethoxyquinoline derivatives as G9a inhibitors

por Srimongkolpithak, Nitipol, Sundriyal, Sandeep, Li, Fengling, Vedadi, Masoud, Fuchter, Matthew J.
Publicado 2014

Biophysical characterization of recombinant proteins: A key to higher structural genomics success

por Vedadi, Masoud, Arrowsmith, Cheryl H., Allali-Hassani, Abdellah, Senisterra, Guillermo, Wasney, Gregory A.
Publicado 2010

Targeting human SET1/MLL family of proteins

por Vedadi, Masoud, Blazer, Levi, Eram, Mohammad S., Barsyte‐Lovejoy, Dalia, Arrowsmith, Cheryl H., Hajian, Taraneh
Publicado 2017

Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12

por Chen, Zhuoyao, Wasney, Gregory A., Picaud, Sarah, Filippakopoulos, Panagis, Vedadi, Masoud, D'Angiolella, Vincenzo, Bullock, Alex N.
Publicado 2020

A High-Throughput Radioactivity-Based Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex

por Khalili Yazdi, Aliakbar, Li, Fengling, Devkota, Kanchan, Perveen, Sumera, Ghiabi, Pegah, Hajian, Taraneh, Bolotokova, Albina, Vedadi, Masoud
Publicado 2021

PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase

por Blazer, Levi L., Lima-Fernandes, Evelyne, Gibson, Elisa, Eram, Mohammad S., Loppnau, Peter, Arrowsmith, Cheryl H., Schapira, Matthieu, Vedadi, Masoud
Publicado 2016

Crystal Structures of Human Choline Kinase Isoforms in Complex with Hemicholinium-3: SINGLE AMINO ACID NEAR THE ACTIVE SITE INFLUENCES INHIBITOR SENSITIVITY

por Hong, Bum Soo, Allali-Hassani, Abdellah, Tempel, Wolfram, Finerty, Patrick J., MacKenzie, Farrell, Dimov, Svetoslav, Vedadi, Masoud, Park, Hee-Won
Publicado 2010

Structural Studies of a Four-MBT Repeat Protein MBTD1

por Eryilmaz, Jitka, Pan, Patricia, Amaya, Maria F., Allali-Hassani, Abdellah, Dong, Aiping, Adams-Cioaba, Melanie A., MacKenzie, Farrell, Vedadi, Masoud, Min, Jinrong
Publicado 2009

Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2

por Adams-Cioaba, Melanie A., Guo, Yahong, Bian, ChuanBing, Amaya, Maria F., Lam, Robert, Wasney, Gregory A., Vedadi, Masoud, Xu, Chao, Min, Jinrong
Publicado 2010

Characterization of 14-3-3 Proteins from Cryptosporidium parvum

por Brokx, Stephen J., Wernimont, Amy K., Dong, Aiping, Wasney, Gregory A., Lin, Yu-Hui, Lew, Jocelyne, Vedadi, Masoud, Lee, Wen Hwa, Hui, Raymond
Publicado 2011

Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions

por Yu, Dan, Horton, John R, Yang, Jie, Hajian, Taraneh, Vedadi, Masoud, Sagum, Cari A, Bedford, Mark T, Blumenthal, Robert M, Zhang, Xing, Cheng, Xiaodong
Publicado 2021

Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X

por Paudel, Prajwal, Zhang, Qi, Leung, Charles, Greenberg, Harrison C., Guo, Yusong, Chern, Yi-Hsuan, Dong, Aiping, Li, Yanjun, Vedadi, Masoud, Zhuang, Zhihao, Tong, Yufeng
Publicado 2019

Human MettL3–MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro

por Woodcock, Clayton B., Yu, Dan, Hajian, Taraneh, Li, Jia, Huang, Yun, Dai, Nan, Corrêa, Ivan R., Wu, Tao, Vedadi, Masoud, Zhang, Xing, Cheng, Xiaodong
Publicado 2019

Structural insights into the inhibited states of the Mer receptor tyrosine kinase

por Huang, Xudong, Finerty, Patrick, Walker, John R., Butler-Cole, Christine, Vedadi, Masoud, Schapira, Matthieu, Parker, Sirlester A., Turk, Benjamin E., Thompson, Debra A., Dhe-Paganon, Sirano
Publicado 2009

Recognition and Specificity Determinants of the Human Cbx Chromodomains

por Kaustov, Lilia, Ouyang, Hui, Amaya, Maria, Lemak, Alexander, Nady, Nataliya, Duan, Shili, Wasney, Gregory A., Li, Zhihong, Vedadi, Masoud, Schapira, Matthieu, Min, Jinrong, Arrowsmith, Cheryl H.
Publicado 2011

Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations

por Wu, Hong, Zeng, Hong, Dong, Aiping, Li, Fengling, He, Hao, Senisterra, Guillermo, Seitova, Alma, Duan, Shili, Brown, Peter J., Vedadi, Masoud, Arrowsmith, Cheryl H., Schapira, Matthieu
Publicado 2013

Molecular basis for the methylation specificity of ATXR5 for histone H3

por Bergamin, Elisa, Sarvan, Sabina, Malette, Josée, Eram, Mohammad S., Yeung, Sylvain, Mongeon, Vanessa, Joshi, Monika, Brunzelle, Joseph S., Michaels, Scott D., Blais, Alexandre, Vedadi, Masoud, Couture, Jean-François
Publicado 2017

Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity

por Sundriyal, Sandeep, Chen, Patty B., Lubin, Alexandra S., Lueg, Gregor A., Li, Fengling, White, Andrew J. P., Malmquist, Nicholas A., Vedadi, Masoud, Scherf, Artur, Fuchter, Matthew J.
Publicado 2017

Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase

por Zhou, Jujun, Deng, Youchao, Iyamu, Iredia D., Horton, John R., Yu, Dan, Hajian, Taraneh, Vedadi, Masoud, Rotili, Dante, Mai, Antonello, Blumenthal, Robert M., Zhang, Xing, Huang, Rong, Cheng, Xiaodong
Publicado 2023