Characterizing Sex Differences in Mitochondrial Dysfunction After Severe Traumatic Brain Injury in Mice

por Kalimon, Olivia J., Vekaria, Hemendra J., Velmurugan, Gopal V., Hubbard, W. Brad, Sullivan, Patrick G.
Publicado 2023

Temporal changes in inflammatory mitochondria-enriched microRNAs following traumatic brain injury and effects of miR-146a nanoparticle delivery

por Wang, Wang-Xia, Prajapati, Paresh, Vekaria, Hemendra J., Spry, Malinda, Cloud, Amber L., Sullivan, Patrick G., Springer, Joe E.
Publicado 2020

LRP1 Deficiency Promotes Mitostasis in Response to Oxidative Stress: Implications for Mitochondrial Targeting after Traumatic Brain Injury

por Velmurugan, Gopal V., Hubbard, W. Brad, Prajapati, Paresh, Vekaria, Hemendra J., Patel, Samir P., Rabchevsky, Alexander G., Sullivan, Patrick G.
Publicado 2023

Inhibition of acid sphingomyelinase reduces reactive astrocyte secretion of mitotoxic extracellular vesicles and improves Alzheimer’s disease pathology in the 5xFAD mouse

por Crivelli, Simone M., Quadri, Zainuddin, Vekaria, Hemendra J., Zhu, Zhihui, Tripathi, Priyanka, Elsherbini, Ahmed, Zhang, Liping, Sullivan, Patrick G., Bieberich, Erhard
Publicado 2023

Pioglitazone restores mitochondrial function but does not spare cortical tissue following mild brain contusion

por Hubbard, W Brad, Vekaria, Hemendra J, Kalimon, Olivia J, Spry, Malinda L, Brown, Emily P, Kilbaugh, Todd J, Sullivan, Patrick G
Publicado 2023

Novel Isolation Method Reveals Sex-Specific Composition and Neurotoxicity of Small Extracellular Vesicles in a Mouse Model of Alzheimer’s Disease

por Elsherbini, Ahmed, Zhu, Zhihui, Quadri, Zainuddin, Crivelli, Simone M., Ren, Xiaojia, Vekaria, Hemendra J., Tripathi, Priyanka, Zhang, Liping, Zhi, Wenbo, Bieberich, Erhard
Publicado 2023

Mitochondrial Dysfunction After Repeated Mild Blast Traumatic Brain Injury Is Attenuated by a Mild Mitochondrial Uncoupling Prodrug

por Hubbard, W. Brad, Vekaria, Hemendra J., Velmurugan, Gopal V., Kalimon, Olivia J., Prajapati, Paresh, Brown, Emily, Geisler, John G., Sullivan, Patrick G.
Publicado 2023

Mitochondria exert age-divergent effects on recovery from spinal cord injury

por Stewart, Andrew N., McFarlane, Katelyn E., Vekaria, Hemendra J., Bailey, William M., Slone, Stacey A., Tranthem, Lauren A., Zhang, Bei, Patel, Samir P., Sullivan, Patrick G., Gensel, John C.
Publicado 2021

Clinically relevant mitochondrial-targeted therapy improves chronic outcomes after traumatic brain injury

por Hubbard, W Brad, Spry, Malinda L, Gooch, Jennifer L, Cloud, Amber L, Vekaria, Hemendra J, Burden, Shawn, Powell, David K, Berkowitz, Bruce A, Geldenhuys, Werner J, Harris, Neil G, Sullivan, Patrick G
Publicado 2021

Pioglitazone does not synergize with mirabegron to increase beige fat or further improve glucose metabolism

por Finlin, Brian S., Memetimin, Hasiyet, Zhu, Beibei, Confides, Amy L., Vekaria, Hemendra J., El Khouli, Riham H., Johnson, Zachary R., Westgate, Philip M., Chen, Jianzhong, Morris, Andrew J., Sullivan, Patrick G., Dupont-Versteegden, Esther E., Kern, Philip A.
Publicado 2021