Diverse Roles of TRPV4 in Macrophages: A Need for Unbiased Profiling

por Nguyen, Thanh-Nhan, Siddiqui, Ghizal, Veldhuis, Nicholas A., Poole, Daniel P.
Publicado 2022

Internalized GPCRs as Potential Therapeutic Targets for the Management of Pain

por Retamal, Jeffri S., Ramírez-García, Paulina D., Shenoy, Priyank A., Poole, Daniel P., Veldhuis, Nicholas A.
Publicado 2019

Selective G protein signaling driven by Substance P-Neurokinin Receptor dynamics

por Harris, Julian A., Faust, Bryan, Gondin, Arisbel B., Dämgen, Marc André, Suomivuori, Carl-Mikael, Veldhuis, Nicholas A., Cheng, Yifan, Dror, Ron O., Thal, David M., Manglik, Aashish
Publicado 2021

A Novel Ultra-Stable, Monomeric Green Fluorescent Protein For Direct Volumetric Imaging of Whole Organs Using CLARITY

por Scott, Daniel J., Gunn, Natalie J., Yong, Kelvin J., Wimmer, Verena C., Veldhuis, Nicholas A., Challis, Leesa M., Haidar, Mouna, Petrou, Steven, Bathgate, Ross A. D., Griffin, Michael D. W.
Publicado 2018

Mu and Delta Opioid Receptors Are Coexpressed and Functionally Interact in the Enteric Nervous System of the Mouse Colon

por DiCello, Jesse J., Carbone, Simona E., Saito, Ayame, Rajasekhar, Pradeep, Ceredig, Rhian A., Pham, Vi, Valant, Celine, Christopoulos, Arthur, Veldhuis, Nicholas A., Canals, Meritxell, Massotte, Dominique, Poole, Daniel P.
Publicado 2019

Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief

por Hegron, Alan, Peach, Chloe J., Tonello, Raquel, Seemann, Philipp, Teng, Shavonne, Latorre, Rocco, Huebner, Harald, Weikert, Dorothee, Rientjes, Jeanette, Veldhuis, Nicholas A., Poole, Daniel P., Jensen, Dane D., Thomsen, Alex R. B., Schmidt, Brian L., Imlach, Wendy L., Gmeiner, Peter, Bunnett, Nigel W.
Publicado 2023

Serotonin-induced vascular permeability is mediated by transient receptor potential vanilloid 4 in the airways and upper gastrointestinal tract of mice

por Retamal, Jeffri S., Grace, Megan S., Dill, Larissa K., Ramirez-Garcia, Paulina, Peng, Scott, Gondin, Arisbel B., Bennetts, Felix, Alvi, Sadia, Rajasekhar, Pradeep, Almazi, Juhura G., Carbone, Simona E., Bunnett, Nigel W., Davis, Thomas P., Veldhuis, Nicholas A., Poole, Daniel P., McIntyre, Peter
Publicado 2021

Mice expressing fluorescent PAR(2) reveal that endocytosis mediates colonic inflammation and pain

por Latorre, Rocco, Hegron, Alan, Peach, Chloe J., Teng, Shavonne, Tonello, Raquel, Retamal, Jeffri S., Klein-Cloud, Rafael, Bok, Diana, Jensen, Dane D., Gottesman-Katz, Lena, Rientjes, Jeanette, Veldhuis, Nicholas A., Poole, Daniel P., Schmidt, Brian L., Pothoulakis, Charalabos H., Rankin, Carl, Xie, Ying, Koon, Hon Wai, Bunnett, Nigel W.
Publicado 2022

A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes

por Mai, Quynh N., Shenoy, Priyank, Quach, Tim, Retamal, Jeffri S., Gondin, Arisbel B., Yeatman, Holly R., Aurelio, Luigi, Conner, Joshua W., Poole, Daniel P., Canals, Meritxell, Nowell, Cameron J., Graham, Bim, Davis, Thomas P., Briddon, Stephen J., Hill, Stephen J., Porter, Christopher J.H., Bunnett, Nigel W., Halls, Michelle L., Veldhuis, Nicholas A.
Publicado 2021