Molecular dynamics simulations indicate an induced-fit mechanism for LSD1/CoREST-H3-histone molecular recognition

por Vellore, Nadeem A, Baron, Riccardo
Publicado 2013

Radotinib is an Effective Inhibitor of Native and Kinase Domain-Mutant BCR-ABL1

por Zabriskie, Matthew S., Vellore, Nadeem A., Gantz, Kevin C., Deininger, Michael W., O’Hare, Thomas
Publicado 2015

Expanding the Druggable Space of the LSD1/CoREST Epigenetic Target: New Potential Binding Regions for Drug-Like Molecules, Peptides, Protein Partners, and Chromatin

por Robertson, James C., Hurley, Nate C., Tortorici, Marcello, Ciossani, Giuseppe, Borrello, Maria Teresa, Vellore, Nadeem A., Ganesan, A., Mattevi, Andrea, Baron, Riccardo
Publicado 2013

A marine analgesic peptide, Contulakin-G, and neurotensin are distinct agonists for neurotensin receptors: uncovering structural determinants of desensitization properties

por Lee, Hee-Kyoung, Zhang, Liuyin, Smith, Misty D., Walewska, Aleksandra, Vellore, Nadeem A., Baron, Riccardo, McIntosh, J. Michael, White, H. Steve, Olivera, Baldomero M., Bulaj, Grzegorz
Publicado 2015

Mechanisms of Resistance to the BCR-ABL1 Allosteric Inhibitor Asciminib

por Qiang, Wang, Antelope, Orlando, Zabriskie, Matthew S., Pomicter, Anthony D., Vellore, Nadeem A., Szankasi, Philippe, Rea, Delphine, Cayuela, Jean Michel, Kelley, Todd W., Deininger, Michael W., O’Hare, Thomas
Publicado 2017

Combined STAT3 and BCR-ABL1 Inhibition Induces Synthetic Lethality in Therapy-Resistant Chronic Myeloid Leukemia

por Eiring, Anna M., Page, Brent D. G., Kraft, Ira L., Mason, Clinton C., Vellore, Nadeem A., Resetca, Diana, Zabriskie, Matthew S., Zhang, Tian Y., Khorashad, Jamshid S., Engar, Alexander J., Reynolds, Kimberly R., Anderson, David J., Senina, Anna, Pomicter, Anthony D., Arpin, Carolynn C., Ahmad, Shazia, Heaton, William L., Tantravahi, Srinivas K., Todic, Aleksandra, Moriggl, Richard, Wilson, Derek J., Baron, Riccardo, O'Hare, Thomas, Gunning, Patrick T., Deininger, Michael W.
Publicado 2014

Identification of small-molecule protein–protein interaction inhibitors for NKG2D

por Thompson, Aaron A., Harbut, Michael B., Kung, Pei-Pei, Karpowich, Nathan K., Branson, Jeffrey D., Grant, Joanna C., Hagan, Deborah, Pascual, Heather A., Bai, Guoyun, Zavareh, Reza Beheshti, Coate, Heather R., Collins, Bernard C., Côte, Marjorie, Gelin, Christine F., Damm-Ganamet, Kelly L., Gholami, Hadi, Huff, Adam R., Limon, Luis, Lumb, Kevin J., Mak, Puiying A., Nakafuku, Kohki M., Price, Edmund V., Shih, Amy Y., Tootoonchi, Mandana, Vellore, Nadeem A., Wang, Jocelyn, Wei, Na, Ziff, Jeannie, Berger, Scott B., Edwards, James P., Gardet, Agnès, Sun, Siquan, Towne, Jennifer E., Venable, Jennifer D., Shi, Zhicai, Venkatesan, Hariharan, Rives, Marie-Laure, Sharma, Sujata, Shireman, Brock T., Allen, Samantha J.
Publicado 2023