Cyanobacterial Metabolite Calothrixins: Recent Advances in Synthesis and Biological Evaluation

por Xu, Su, Nijampatnam, Bhavitavya, Dutta, Shilpa, Velu, Sadanandan E.
Publicado 2016

Antibacterial and Antibiofilm Activities of Makaluvamine Analogs

por Nijampatnam, Bhavitavya, Nadkarni, Dwayaja H., Wu, Hui, Velu, Sadanandan E.
Publicado 2014

Nonsense-mediated decay controls the reactivation of the oncogenic herpesviruses EBV and KSHV

por van Gent, Michiel, Reich, Adrian, Velu, Sadanandan E., Gack, Michaela U.
Publicado 2021

Synthesis of Pyrroloquinones via a CAN Mediated Oxidative Free Radical Reaction of 1,3-Dicarbonyl Compounds with Aminoquinones

por Nguyen, Thao, Nadkarni, Dwayaja, Dutta, Shilpa, Xu, Su, Kim, Sanghun, Murugesan, Srinivasan, Velu, Sadanandan
Publicado 2013

Inhibition of Streptococcus mutans Biofilms by the Natural Stilbene Piceatannol Through the Inhibition of Glucosyltransferases

por Nijampatnam, Bhavitavya, Zhang, Hua, Cai, Xia, Michalek, Suzanne M., Wu, Hui, Velu, Sadanandan E.
Publicado 2018

A Novel Marine Natural Product Derived Pyrroloiminoquinone with Potent Activity against Skin Cancer Cells

por Cowan, Jaden, Shadab, Mohammad, Nadkarni, Dwayaja H., KC, Kailash, Velu, Sadanandan E., Yusuf, Nabiha
Publicado 2019

Honokiol inhibits the growth of head and neck squamous cell carcinoma by targeting epidermal growth factor receptor

por Singh, Tripti, Gupta, Nirzari A., Xu, Su, Prasad, Ram, Velu, Sadanandan E., Katiyar, Santosh K.
Publicado 2015

Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic Virulence

por Zhang, Qiong, Nijampatnam, Bhavitavya, Hua, Zhang, Nguyen, Thao, Zou, Jing, Cai, Xia, Michalek, Suzanne M., Velu, Sadanandan E., Wu, Hui
Publicado 2017

Synthetic Makaluvamine Analogs Decrease c-Kit Expression and Are Cytotoxic to Neuroendocrine Tumor Cells

por Aburjania, Zviadi, Whitt, Jason D., Jang, Samuel, Nadkarni, Dwayaja H., Chen, Herbert, Rose, J. Bart, Velu, Sadanandan E., Jaskula-Sztul, Renata
Publicado 2020

Pharmacological and nutritional targeting of voltage-gated sodium channels in the treatment of cancers

por Lopez-Charcas, Osbaldo, Pukkanasut, Piyasuda, Velu, Sadanandan E., Brackenbury, William J., Hales, Tim G., Besson, Pierre, Gomora, Juan Carlos, Roger, Sébastien
Publicado 2021

Preclinical Evaluation of Anticancer Efficacy and Pharmacological Properties of FBA-TPQ, a Novel Synthetic Makaluvamine Analog

por Zhang, Xiangrong, Xu, Hongxia, Zhang, Xu, Voruganti, Sukesh, Murugesan, Srinivasan, Nadkarni, Dwayaja H., Velu, Sadanandan E., Wang, Ming-Hai, Wang, Wei, Zhang, Ruiwen
Publicado 2012

Attenuation of Nonsense-Mediated mRNA Decay Enhances In Vivo Nonsense Suppression

por Keeling, Kim M., Wang, Dan, Dai, Yanying, Murugesan, Srinivasan, Chenna, Balachandra, Clark, Jeremy, Belakhov, Valery, Kandasamy, Jeyakumar, Velu, Sadanandan E., Baasov, Timor, Bedwell, David M.
Publicado 2013

Toll-like receptor 9 expression is associated with breast cancer sensitivity to the growth inhibitory effects of bisphosphonates in vitro and in vivo

por Sandholm, Jouko, Lehtimäki, Jaakko, Ishizu, Tamiko, Velu, Sadanandan E., Clark, Jeremy, Härkönen, Pirkko, Jukkola-Vuorinen, Arja, Schrey, Aleksi, Harris, Kevin W., Tuomela, Johanna M., Selander, Katri S.
Publicado 2016

Preclinical Pharmacology of BA-TPQ, a Novel Synthetic Iminoquinone Anticancer Agent

por Ezell, Scharri J., Li, Haibo, Xu, Hongxia, Zhang, Xiangrong, Gurpinar, Evrim, Zhang, Xu, Rayburn, Elizabeth R., Sommers, Charnell I., Yang, Xinyi, Velu, Sadanandan E., Wang, Wei, Zhang, Ruiwen
Publicado 2010

Experimental Therapy of Ovarian Cancer with Synthetic Makaluvamine Analog: In Vitro and In Vivo Anticancer Activity and Molecular Mechanisms of Action

por Chen, Tao, Xu, Yi, Guo, He, Liu, Yanling, Hu, Pingting, Yang, Xinying, Li, Xiaoguang, Ge, Shichao, Velu, Sadanandan E., Nadkarni, Dwayaja H., Wang, Wei, Zhang, Ruiwen, Wang, Hui
Publicado 2011

Voltage-Gated Sodium Channel Na(V)1.7 Inhibitors with Potent Anticancer Activities in Medullary Thyroid Cancer Cells

por Pukkanasut, Piyasuda, Whitt, Jason, Guenter, Rachael, Lynch, Shannon E., Gallegos, Carlos, Rosendo-Pineda, Margarita Jacaranda, Gomora, Juan Carlos, Chen, Herbert, Lin, Diana, Sorace, Anna, Jaskula-Sztul, Renata, Velu, Sadanandan E.
Publicado 2023

A Novel Class of Mitochondria-Targeted Soft Electrophiles Modifies Mitochondrial Proteins and Inhibits Mitochondrial Metabolism in Breast Cancer Cells through Redox Mechanisms

por Vayalil, Praveen K., Oh, Joo-Yeun, Zhou, Fen, Diers, Anne R., Smith, M. Ryan, Golzarian, Hafez, Oliver, Patsy G., Smith, Robin A. J., Murphy, Michael P., Velu, Sadanandan E., Landar, Aimee
Publicado 2015

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas

por Desai, Chandni, Thomason, Jon, Kohlmeyer, Jordan L., Reisetter, Anna C., Ahirwar, Parmanand, Jahanseir, Khadijeh, Leidinger, Mariah, Ofori-Amanfo, Georgina, Fritchie, Karen, Velu, Sadanandan E., Breheny, Patrick, Quelle, Dawn E., Tanas, Munir R.
Publicado 2021

Voltage-Gated Sodium Channel Na(V)1.5 Controls NHE−1−Dependent Invasive Properties in Colon Cancer Cells

por Lopez-Charcas, Osbaldo, Poisson, Lucile, Benouna, Oumnia, Lemoine, Roxane, Chadet, Stéphanie, Pétereau, Adrien, Lahlou, Widad, Guyétant, Serge, Ouaissi, Mehdi, Pukkanasut, Piyasuda, Dutta, Shilpa, Velu, Sadanandan E., Besson, Pierre, Moussata, Driffa, Roger, Sébastien
Publicado 2022

Mitochondrial thiol modification by a targeted electrophile inhibits metabolism in breast adenocarcinoma cells by inhibiting enzyme activity and protein levels

por Smith, M. Ryan, Vayalil, Praveen K., Zhou, Fen, Benavides, Gloria A., Beggs, Reena R., Golzarian, Hafez, Nijampatnam, Bhavitavya, Oliver, Patsy G., Smith, Robin A.J., Murphy, Michael P., Velu, Sadanandan E., Landar, Aimee
Publicado 2016