Autophagy inhibition by chloroquine and hydroxychloroquine could adversely affect acute kidney injury and other organ injury in critically ill patients with COVID-19

por Edelstein, Charles L., Venkatachalam, Manjeri A., Dong, Zheng
Publicado 2020

A Novel Role for MAP1 LC3 in Non-Autophagic Cytoplasmic Vacuolation Death of Cancer Cells

por Kar, Rekha, Singha, Prajjal K, Venkatachalam, Manjeri A, Saikumar, Pothana
Publicado 2009

TGF-β induced TMEPAI/PMEPA1 inhibits canonical Smad signaling through R-Smad sequestration and promotes non-canonical PI3K/Akt signaling by reducing PTEN in triple negative breast...

por Singha, Prajjal K., Pandeswara, Srilakshmi, Geng, Hui, Lan, Rongpei, Venkatachalam, Manjeri A., Saikumar, Pothana
Publicado 2014

PI3K regulation of the SKP-2/p27 axis through mTORC2

por Shanmugasundaram, Karthigayan, Block, Karen, Nayak, Bijaya K., Livi, Carolina B., Venkatachalam, Manjeri A., Sudarshan, Sunil
Publicado 2012

Increased Smad3 and reduced Smad2 levels mediate the functional switch of TGF-β from growth suppressor to growth and metastasis promoter through TMEPAI/PMEPA1 in triple negative br...

por Singha, Prajjal K., Pandeswara, Srilakshmi, Geng, Hui, Lan, Rongpei, Venkatachalam, Manjeri A., Dobi, Albert, Srivastava, Shiv, Saikumar, Pothana
Publicado 2019

Proximal tubular epithelial insulin receptor mediates high-fat diet–induced kidney injury

por Lee, Hak Joo, Mariappan, Meenalakshmi M., Norton, Luke, Bakewell, Terry, Feliers, Denis, Oh, Sae Byeol, Donati, Andrew, Rubannelsonkumar, Cherubina S., Venkatachalam, Manjeri A., Harris, Stephen E., Rubera, Isabelle, Tauc, Michel, Ghosh Choudhury, Goutam, Kahn, C. Ronald, Sharma, Kumar, DeFronzo, Ralph A., Kasinath, Balakuntalam S.
Publicado 2021

Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients

por Sharma, Kumar, Zhang, Guanshi, Hansen, Jens, Bjornstad, Petter, Lee, Hak Joo, Menon, Rajasree, Hejazi, Leila, Liu, Jian-Jun, Franzone, Anthony, Looker, Helen C., Choi, Byeong Yeob, Fernandez, Roman, Venkatachalam, Manjeri A., Kugathasan, Luxcia, Sridhar, Vikas S., Natarajan, Loki, Zhang, Jing, Sharma, Varun S., Kwan, Brian, Waikar, Sushrut S., Himmelfarb, Jonathan, Tuttle, Katherine R., Kestenbaum, Bryan, Fuhrer, Tobias, Feldman, Harold I., de Boer, Ian H., Tucci, Fabio C., Sedor, John, Heerspink, Hiddo Lambers, Schaub, Jennifer, Otto, Edgar A., Hodgin, Jeffrey B., Kretzler, Matthias, Anderton, Christopher R., Alexandrov, Theodore, Cherney, David, Lim, Su Chi, Nelson, Robert G., Gelfond, Jonathan, Iyengar, Ravi
Publicado 2023