Homology-directed gene-editing approaches for hematopoietic stem and progenitor cell gene therapy

por Azhagiri, Manoj Kumar K., Babu, Prathibha, Venkatesan, Vigneshwaran, Thangavel, Saravanabhavan
Publicado 2021

Diosgenin enhances liposome-enabled nucleic acid delivery and CRISPR/Cas9-mediated gene editing by modulating endocytic pathways

por Lohchania, Brijesh, Christopher, Abisha Crystal, Arjunan, Porkizhi, Mahalingam, Gokulnath, Kathirvelu, Durga, Prasannan, Aishwarya, Venkatesan, Vigneshwaran, Taneja, Pankaj, KM, Mohan Kumar, Thangavel, Saravanabhavan, Marepally, Srujan
Publicado 2023

Erythroid lineage-specific lentiviral RNAi vectors suitable for molecular functional studies and therapeutic applications

por Bagchi, Abhirup, Devaraju, Nivedhitha, Chambayil, Karthik, Rajendiran, Vignesh, Venkatesan, Vigneshwaran, Sayed, Nilofer, Pai, Aswin Anand, Nath, Aneesha, David, Ernest, Nakamura, Yukio, Balasubramanian, Poonkuzhali, Srivastava, Alok, Thangavel, Saravanabhavan, Mohankumar, Kumarasamypet M., Velayudhan, Shaji R.
Publicado 2022

Direct Generation of Immortalized Erythroid Progenitor Cell Lines from Peripheral Blood Mononuclear Cells

por Bagchi, Abhirup, Nath, Aneesha, Thamodaran, Vasanth, Ijee, Smitha, Palani, Dhavapriya, Rajendiran, Vignesh, Venkatesan, Vigneshwaran, Datari, Phaneendra, Pai, Aswin Anand, Janet, Nancy Beryl, Balasubramanian, Poonkuzhali, Nakamura, Yukio, Srivastava, Alok, Mohankumar, Kumarasamypet Murugesan, Thangavel, Saravanabhavan, Velayudhan, Shaji R.
Publicado 2021

The CCR5 Gene Edited CD34(+)CD90(+) Hematopoietic Stem Cell Population Serves as an Optimal Graft Source for HIV Gene Therapy

por Karuppusamy, Karthik V., Demosthenes, John Paul, Venkatesan, Vigneshwaran, Christopher, Abisha Crystal, Babu, Prathibha, Azhagiri, Manojkumar K., Jacob, Annlin, Ramalingam, Veena Vadhini, Rangaraj, Sumathi, Murugesan, Mohankumar Kumarasamypet, Marepally, Srujan Kumar, Varghese, George M., Srivastava, Alok, Kannangai, Rajesh, Thangavel, Saravanabhavan
Publicado 2022

Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies

por Venkatesan, Vigneshwaran, Christopher, Abisha Crystal, Rhiel, Manuel, Azhagiri, Manoj Kumar K., Babu, Prathibha, Walavalkar, Kaivalya, Saravanan, Bharath, Andrieux, Geoffroy, Rangaraj, Sumathi, Srinivasan, Saranya, Karuppusamy, Karthik V., Jacob, Annlin, Bagchi, Abhirup, Pai, Aswin Anand, Nakamura, Yukio, Kurita, Ryo, Balasubramanian, Poonkuzhali, Pai, Rekha, Marepally, Srujan Kumar, Mohankumar, Kumarasamypet Murugesan, Velayudhan, Shaji R., Boerries, Melanie, Notani, Dimple, Cathomen, Toni, Srivastava, Alok, Thangavel, Saravanabhavan
Publicado 2023