Tumour Suppressor Mechanisms in the Control of Chromosome Stability: Insights from BRCA2

por Venkitaraman, Ashok R.
Publicado 2014

Two modules in the BRC repeats of BRCA2 mediate structural and functional interactions with the RAD51 recombinase

por Rajendra, Eeson, Venkitaraman, Ashok R.
Publicado 2010

Micro(mi) RNA-34a targets protein phosphatase (PP)1γ to regulate DNA damage tolerance

por Takeda, Yuko, Venkitaraman, Ashok R
Publicado 2015

Oncogenic KRAS triggers MAPK-dependent errors in mitosis and MYC-dependent sensitivity to anti-mitotic agents

por Perera, David, Venkitaraman, Ashok R.
Publicado 2016

Enhancing Biochemical Resolution by Hyperdimensional Imaging Microscopy

por Esposito, Alessandro, Venkitaraman, Ashok R.
Publicado 2019

Inhibition of Interleukin 7 Receptor Signaling by Antigen Receptor Assembly

por Smart, Fiona M., Venkitaraman, Ashok R.
Publicado 2000

A vertebrate N-end rule degron reveals that Orc6 is required in mitosis for daughter cell abscission

por Bernal, Juan A., Venkitaraman, Ashok R.
Publicado 2011

A cancer-associated mutation inactivates a region of the high-mobility group protein HMG20b essential for cytokinesis

por Lee, MiYoung, Venkitaraman, Ashok R
Publicado 2014

Maximizing the Biochemical Resolving Power of Fluorescence Microscopy

por Esposito, Alessandro, Popleteeva, Marina, Venkitaraman, Ashok R.
Publicado 2013

A kinase-independent function for AURORA-A in replisome assembly during DNA replication initiation

por Guarino Almeida, Estrella, Renaudin, Xavier, Venkitaraman, Ashok R
Publicado 2020

Chromosome instability and carcinogenesis: Insights from murine models of human pancreatic cancer associated with BRCA2 inactivation

por Cassidy, Liam D., Liau, Siong-Seng, Venkitaraman, Ashok R.
Publicado 2013

Pulsatile MAPK Signaling Modulates p53 Activity to Control Cell Fate Decisions at the G2 Checkpoint for DNA Damage

por De, Siddharth, Campbell, Callum, Venkitaraman, Ashok R., Esposito, Alessandro
Publicado 2020

Single-molecule localization microscopy reveals molecular transactions during RAD51 filament assembly at cellular DNA damage sites

por Haas, Kalina T, Lee, MiYoung, Esposito, Alessandro, Venkitaraman, Ashok R
Publicado 2018

BRCA2 Regulates Transcription Elongation by RNA Polymerase II to Prevent R-Loop Accumulation

por Shivji, Mahmud K.K., Renaudin, Xavier, Williams, Çiğdem H., Venkitaraman, Ashok R.
Publicado 2018

Cancer-causing BRCA2 missense mutations disrupt an intracellular protein assembly mechanism to disable genome maintenance

por Lee, Miyoung, Shorthouse, David, Mahen, Robert, Hall, Benjamin A, Venkitaraman, Ashok R
Publicado 2021

BRCA2 deficiency reveals that oxidative stress impairs RNaseH1 function to cripple mitochondrial DNA maintenance

por Renaudin, Xavier, Lee, Miyoung, Shehata, Mona, Surmann, Eva-Maria, Venkitaraman, Ashok R.
Publicado 2021

The Carboxyl Terminus of Brca2 Links the Disassembly of Rad51 Complexes to Mitotic Entry

por Ayoub, Nabieh, Rajendra, Eeson, Su, Xinyi, Jeyasekharan, Anand D., Mahen, Robert, Venkitaraman, Ashok R.
Publicado 2009

A-Type Lamins Maintain the Positional Stability of DNA Damage Repair Foci in Mammalian Nuclei

por Mahen, Robert, Hattori, Hiroyoshi, Lee, Miyoung, Sharma, Pooja, Jeyasekharan, Anand D., Venkitaraman, Ashok R.
Publicado 2013

Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions

por Laraia, Luca, McKenzie, Grahame, Spring, David R., Venkitaraman, Ashok R., Huggins, David J.
Publicado 2015

p53 shapes genome-wide and cell type-specific changes in microRNA expression during the human DNA damage response

por Hattori, Hiroyoshi, Janky, Rekin’s, Nietfeld, Wilfried, Aerts, Stein, Madan Babu, M, Venkitaraman, Ashok R
Publicado 2014