Evidence‐Based Development and Clinical Use of Precision Oncology Therapeutics

por Comment, Leah A., Ward, Ashley F., Schrock, Alexa B., Fabrizio, David, Venstrom, Jeffrey M., Hegde, Priti S., Alexander, Brian M.
Publicado 2020

Individualized genetic makeup that controls natural killer cell function influences the efficacy of isatuximab immunotherapy in patients with multiple myeloma

por Sun, Haibo, Martin, Thomas G, Marra, John, Kong, Denice, Keats, Jonathon, Macé, Sandrine, Chiron, Marielle, Wolf, Jeffrey L, Venstrom, Jeffrey M, Rajalingam, Raja
Publicado 2021

Conversion of Adipose-Derived Stem Cells into Natural Killer-Like Cells with Anti-Tumor Activities in Nude Mice

por Ning, Hongxiu, Lei, Hong-En, Xu, Yong-De, Guan, Rui-Li, Venstrom, Jeffrey M., Lin, Guiting, Lue, Tom F., Xin, Zhongcheng, Lin, Ching-Shwun
Publicado 2014

APOBEC Mutational Signatures in Hormone Receptor–Positive Human Epidermal Growth Factor Receptor 2–Negative Breast Cancers Are Associated With Poor Outcomes on CDK4/6 Inhibitors an...

por Sammons, Sarah, Raskina, Kira, Danziger, Natalie, Alder, Laura, Schrock, Alexa B., Venstrom, Jeffrey M., Knutson, Keith L., Thompson, E. Aubrey, McGregor, Kim, Sokol, Ethan, Chumsri, Saranya
Publicado 2022

ERBB2 Copy Number as a Quantitative Biomarker for Real-World Outcomes to Anti–Human Epidermal Growth Factor Receptor 2 Therapy in Advanced Gastroesophageal Adenocarcinoma

por Zhang, Liangliang, Hamdani, Omar, Gjoerup, Ole, Cho-Phan, Cheryl, Snider, Jeremy, Castellanos, Emily, Nimeiri, Halla, Frampton, Garrett, Venstrom, Jeffrey M., Oxnard, Geoffrey, Klempner, Samuel J., Schrock, Alexa B.
Publicado 2022

Characterization of Non–Small-Cell Lung Cancers With MET Exon 14 Skipping Alterations Detected in Tissue or Liquid: Clinicogenomics and Real-World Treatment Patterns

por Lee, Jessica K., Madison, Russell, Classon, Anthony, Gjoerup, Ole, Rosenzweig, Mark, Frampton, Garrett M., Alexander, Brian M., Oxnard, Geoffrey R., Venstrom, Jeffrey M., Awad, Mark M., Schrock, Alexa B.
Publicado 2021

The Pan-Tumor Landscape of Targetable Kinase Fusions in Circulating Tumor DNA

por Lee, Jessica K., Hazar-Rethinam, Mehlika, Decker, Brennan, Gjoerup, Ole, Madison, Russell W., Lieber, Daniel S., Chung, Jon H., Schrock, Alexa B., Creeden, James, Venstrom, Jeffrey, Alexander, Brian, Oxnard, Geoffrey R.
Publicado 2022

Patients with NSCLCs Harboring Internal Inversions or Deletion Rearrangements of the ALK Gene Have Durable Responses to ALK Kinase Inhibitors

por Schrock, Alexa B, Madison, Russell, Rosenzweig, Mark, Allen, Justin M, Erlich, Rachel L, Wang, Siao-Yi, Chidiac, Tarek, Reddy, Vodur Suresh, Riess, Jonathan W, Yassa, Ahmet Ersin, Shakir, Abdur, Miller, Vincent A, Alexander, Brian M, Venstrom, Jeffrey, McGregor, Kimberly, Ali, Siraj M
Publicado 2020

CDKN2C-Null Leiomyosarcoma: A Novel, Genomically Distinct Class of TP53/RB1–Wild-Type Tumor With Frequent CIC Genomic Alterations and 1p/19q-Codeletion

por Williams, Erik A., Sharaf, Radwa, Decker, Brennan, Werth, Adrienne J., Toma, Helen, Montesion, Meagan, Sokol, Ethan S., Pavlick, Dean C., Shah, Nikunj, Williams, Kevin Jon, Venstrom, Jeffrey M., Alexander, Brian M., Ross, Jeffrey S., Albacker, Lee A., Lin, Douglas I., Ramkissoon, Shakti H., Elvin, Julia A.
Publicado 2020

Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer

por Sivakumar, Smruthy, Jin, Dexter X., Tukachinsky, Hanna, Murugesan, Karthikeyan, McGregor, Kimberly, Danziger, Natalie, Pavlick, Dean, Gjoerup, Ole, Ross, Jeffrey S., Harmon, Robert, Chung, Jon, Decker, Brennan, Dennis, Lucas, Frampton, Garrett M., Molinero, Luciana, Oesterreich, Steffi, Venstrom, Jeffrey M., Oxnard, Geoffrey R., Hegde, Priti S., Sokol, Ethan S.
Publicado 2022

The Genomics of Colorectal Cancer in Populations with African and European Ancestry

por Myer, Parvathi A., Lee, Jessica K., Madison, Russell W., Pradhan, Kith, Newberg, Justin Y., Isasi, Carmen R., Klempner, Samuel J., Frampton, Garrett M., Ross, Jeffery S., Venstrom, Jeffrey M., Schrock, Alexa B., Das, Sudipto, Augenlicht, Leonard, Verma, Amit, Greally, John M., Raj, Srilakshmi M., Goel, Sanjay, Ali, Siraj M.
Publicado 2022

Genomic Profiling of Circulating Tumor DNA From Cerebrospinal Fluid to Guide Clinical Decision Making for Patients With Primary and Metastatic Brain Tumors

por Ramkissoon, Lori A., Pegram, Worthy, Haberberger, James, Danziger, Natalie, Lesser, Glenn, Strowd, Roy, Dahiya, Sonika, Cummings, Thomas J., Bi, Wenya Linda, Abedalthagafi, Malak, Sathyan, Pratheesh, McGregor, Kimberly, Reddy, Prasanth, Severson, Eric, Williams, Erik, Lin, Douglas, Edgerly, Claire, Huang, Richard S. P., Hemmerich, Amanda, Creeden, James, Brown, Charlotte, Venstrom, Jeffrey, Hegde, Priti, Ross, Jeffrey S., Alexander, Brian M., Elvin, Julia, Ramkissoon, Shakti H.
Publicado 2020

Landscape of Biomarkers in Non-small Cell Lung Cancer Using Comprehensive Genomic Profiling and PD-L1 Immunohistochemistry

por Huang, Richard S. P., Severson, Eric, Haberberger, James, Duncan, Daniel L., Hemmerich, Amanda, Edgerly, Claire, Ferguson, N. Lynn, Frampton, Garrett, Owens, Clarence, Williams, Erik, Elvin, Julia, Vergilio, Jo-Anne, Killian, Jonathan Keith, Lin, Douglas, Morley, Samantha, McEwan, Deborah, Holmes, Oliver, Danziger, Natalie, Cohen, Michael B., Sathyan, Pratheesh, McGregor, Kimberly, Reddy, Prasanth, Venstrom, Jeffrey, Anhorn, Rachel, Alexander, Brian, Brown, Charlotte, Ross, Jeffrey S., Ramkissoon, Shakti H.
Publicado 2021

Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma

por Gounder, Mrinal M., Agaram, Narasimhan P., Trabucco, Sally E., Robinson, Victoria, Ferraro, Richard A., Millis, Sherri Z., Krishnan, Anita, Lee, Jessica, Attia, Steven, Abida, Wassim, Drilon, Alexander, Chi, Ping, Angelo, Sandra P. D’, Dickson, Mark A., Keohan, Mary Lou, Kelly, Ciara M., Agulnik, Mark, Chawla, Sant P., Choy, Edwin, Chugh, Rashmi, Meyer, Christian F., Myer, Parvathi A., Moore, Jessica L., Okimoto, Ross A., Pollock, Raphael E., Ravi, Vinod, Singh, Arun S., Somaiah, Neeta, Wagner, Andrew J., Healey, John H., Frampton, Garrett M., Venstrom, Jeffrey M., Ross, Jeffrey S., Ladanyi, Marc, Singer, Samuel, Brennan, Murray F., Schwartz, Gary K., Lazar, Alexander J., Thomas, David M., Maki, Robert G., Tap, William D., Ali, Siraj M., Jin, Dexter X.
Publicado 2022