Reconstructing the molecular life history of gliomas

por Barthel, Floris P., Wesseling, Pieter, Verhaak, Roel G. W.
Publicado 2018

Extrachromosomal DNA (ecDNA): an origin of tumor heterogeneity, genomic remodeling, and drug resistance

por Pecorino, Lauren T., Verhaak, Roel G.W., Henssen, Anton, Mischel, Paul S.
Publicado 2022

Unifying Gene Expression Measures from Multiple Platforms Using Factor Analysis

por Wang, Xin Victoria, Verhaak, Roel G. W., Purdom, Elizabeth, Spellman, Paul T., Speed, Terence P.
Publicado 2011

Hemizygous CDKN2A deletion confers worse survival outcomes in IDHmut-noncodel gliomas

por Kocakavuk, Emre, Johnson, Kevin C, Sabedot, Thais S, Reinhardt, Hans Christian, Noushmehr, Houtan, Verhaak, Roel G W
Publicado 2023

Integrative genomic analyses reveal clinically relevant long non-coding RNA in human cancer

por Du, Zhou, Fei, Teng, Verhaak, Roel G.W., Su, Zhen, Zhang, Yong, Brown, Myles, Chen, Yiwen, Liu, X. Shirley
Publicado 2013

Novel kinase fusion transcripts found in endometrial cancer

por Tamura, Ryo, Yoshihara, Kosuke, Yamawaki, Kaoru, Suda, Kazuaki, Ishiguro, Tatsuya, Adachi, Sosuke, Okuda, Shujiro, Inoue, Ituro, Verhaak, Roel G. W., Enomoto, Takayuki
Publicado 2015

Perspective of mesenchymal transformation in glioblastoma

por Kim, Yona, Varn, Frederick S., Park, Sung-Hye, Yoon, Byung Woo, Park, Hye Ran, Lee, Charles, Verhaak, Roel G. W., Paek, Sun Ha
Publicado 2021

Radiotherapy is associated with a deletion signature that contributes to poor outcomes in cancer patients

por Kocakavuk, Emre, Anderson, Kevin J., Varn, Frederick S., Johnson, Kevin C., Amin, Samirkumar B., Sulman, Erik. P., Lolkema, Martijn P., Barthel, Floris P., Verhaak, Roel G.W.
Publicado 2021

TumorFusions: an integrative resource for cancer-associated transcript fusions

por Hu, Xin, Wang, Qianghu, Tang, Ming, Barthel, Floris, Amin, Samirkumar, Yoshihara, Kosuke, Lang, Frederick M, Martinez-Ledesma, Emmanuel, Lee, Soo Hyun, Zheng, Siyuan, Verhaak, Roel G W
Publicado 2018

The Tandem Duplicator Phenotype Is a Prevalent Genome-Wide Cancer Configuration Driven by Distinct Gene Mutations

por Menghi, Francesca, Barthel, Floris P., Yadav, Vinod, Tang, Ming, Ji, Bo, Tang, Zhonghui, Carter, Gregory W., Ruan, Yijun, Scully, Ralph, Verhaak, Roel G.W., Jonkers, Jos, Liu, Edison T.
Publicado 2018

Lineage-coupled clonal capture identifies clonal evolution mechanisms and vulnerabilities of BRAF(V600E) inhibition resistance in melanoma

por Zhang, Ze-Yan, Ding, Yingwen, Ezhilarasan, Ravesanker, Lhakhang, Tenzin, Wang, Qianghu, Yang, Jie, Modrek, Aram S., Zhang, Hua, Tsirigos, Aristotelis, Futreal, Andrew, Draetta, Giulio F., Verhaak, Roel G. W., Sulman, Erik P.
Publicado 2022

Molecular and clonal evolution in recurrent metastatic gliosarcoma

por Anderson, Kevin J., Tan, Aaron C., Parkinson, Jonathon, Back, Michael, Kastelan, Marina, Newey, Allison, Brewer, Janice, Wheeler, Helen, Hudson, Amanda L., Amin, Samirkumar B., Johnson, Kevin C., Barthel, Floris P., Verhaak, Roel G.W., Khasraw, Mustafa
Publicado 2020

Driver Mutations Dictate the Immunologic Landscape and Response to Checkpoint Immunotherapy of Glioblastoma

por Yeo, Alan T., Shah, Rushil, Aliazis, Konstantinos, Pal, Rinku, Xu, Tuoye, Zhang, Piyan, Rawal, Shruti, Rose, Christopher M., Varn, Frederick S., Appleman, Vicky A., Yoon, Joon, Varma, Hemant, Gygi, Steven P., Verhaak, Roel G.W., Boussiotis, Vassiliki A., Charest, Al
Publicado 2023

Inferring tumour purity and stromal and immune cell admixture from expression data

por Yoshihara, Kosuke, Shahmoradgoli, Maria, Martínez, Emmanuel, Vegesna, Rahulsimham, Kim, Hoon, Torres-Garcia, Wandaliz, Treviño, Victor, Shen, Hui, Laird, Peter W., Levine, Douglas A., Carter, Scott L., Getz, Gad, Stemke-Hale, Katherine, Mills, Gordon B., Verhaak, Roel G.W.
Publicado 2013

Spatiotemporal dynamics of clonal selection and diversification in normal endometrial epithelium

por Yamaguchi, Manako, Nakaoka, Hirofumi, Suda, Kazuaki, Yoshihara, Kosuke, Ishiguro, Tatsuya, Yachida, Nozomi, Saito, Kyota, Ueda, Haruka, Sugino, Kentaro, Mori, Yutaro, Yamawaki, Kaoru, Tamura, Ryo, Revathidevi, Sundaramoorthy, Motoyama, Teiichi, Tainaka, Kazuki, Verhaak, Roel G. W., Inoue, Ituro, Enomoto, Takayuki
Publicado 2022

GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data

por Ajaib, Shoaib, Lodha, Disha, Pollock, Steven, Hemmings, Gemma, Finetti, Martina A, Gusnanto, Arief, Chakrabarty, Aruna, Ismail, Azzam, Wilson, Erica, Varn, Frederick S, Hunter, Bethany, Filby, Andrew, Brockman, Asa A, McDonald, David, Verhaak, Roel G W, Ihrie, Rebecca A, Stead, Lucy F
Publicado 2023

Transformation by the R Enantiomer of 2-Hydroxyglutarate Linked to EglN Activation

por Koivunen, Peppi, Lee, Sungwoo, Duncan, Christopher G., Lopez, Giselle, Lu, Gang, Ramkissoon, Shakti, Losman, Julie A., Joensuu, Päivi, Bergmann, Ulrich, Gross, Stefan, Travins, Jeremy, Weiss, Samuel, Looper, Ryan, Ligon, Keith L., Verhaak, Roel G.W., Yan, Hai, Kaelin, William G.
Publicado 2012

Biphasic components of sarcomatoid clear cell renal cell carcinomas are molecularly similar to each other, but distinct from, non‐sarcomatoid renal carcinomas

por Sircar, Kanishka, Yoo, Suk‐Young, Majewski, Tadeusz, Wani, Khalida, Patel, Lalit R., Voicu, Horatiu, Torres‐Garcia, Wandaliz, Verhaak, Roel G. W., Tannir, Nizar, Karam, Jose A., Jonasch, Eric, Wood, Christopher G., Tamboli, Pheroze, Baggerly, Keith A., Aldape, Kenneth D., Czerniak, Bogdan
Publicado 2015

Suppression of Lung Adenocarcinoma Progression by Nkx2-1

por Winslow, Monte M., Dayton, Talya L., Verhaak, Roel G. W., Kim-Kiselak, Caroline, Snyder, Eric L., Feldser, David M., Hubbard, Diana D., DuPage, Michel J., Whittaker, Charles A., Hoersch, Sebastian, Yoon, Stephanie, Crowley, Denise, Bronson, Roderick T., Chiang, Derek Y., Meyerson, Matthew, Jacks, Tyler
Publicado 2011

Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma

por Akgül, Seçkin, Li, Yinghua, Zheng, Siyuan, Kool, Marcel, Treisman, Daniel M., Li, Chaoyang, Wang, Yuan, Gröbner, Susanne, Ikenoue, Tsuneo, Shen, Yiping, Camelo-Piragua, Sandra, Tomasek, Gerald, Stark, Sebastian, Guduguntla, Vinay, Gusella, James F., Guan, Kun-Liang, Pfister, Stefan M., Verhaak, Roel G.W., Zhu, Yuan
Publicado 2018