Inducible expression of human C9ORF72 36× G(4)C(2) hexanucleotide repeats is sufficient to cause RAN translation and rapid muscular atrophy in mice

por Riemslagh, Fréderike W., van der Toorn, Esmay C., Verhagen, Rob F. M., Maas, Alex, Bosman, Laurens W. J., Hukema, Renate K., Willemsen, Rob
Publicado 2021

Lack of a Clear Behavioral Phenotype in an Inducible FXTAS Mouse Model Despite the Presence of Neuronal FMRpolyG-Positive Aggregates

por Haify, Saif N., Mankoe, Ruchira S. D., Boumeester, Valerie, van der Toorn, Esmay C., Verhagen, Rob F. M., Willemsen, Rob, Hukema, Renate K., Bosman, Laurens W. J.
Publicado 2020

Reduction of oxidative stress suppresses poly-GR-mediated toxicity in zebrafish embryos

por Riemslagh, Fréderike W., Verhagen, Rob F. M., van der Toorn, Esmay C., Smits, Daphne J., Quint, Wim H., van der Linde, Herma C., van Ham, Tjakko J., Willemsen, Rob
Publicado 2021