A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V

por Rohaim, Ahmed, Vermeulen, Bram J. A., Li, Jing, Kümmerer, Felix, Napoli, Federico, Blachowicz, Lydia, Medeiros-Silva, João, Roux, Benoît, Weingarth, Markus
Publicado 2022

Reconstitution of the recombinant human γ-tubulin ring complex

por Würtz, Martin, Böhler, Anna, Neuner, Annett, Zupa, Erik, Rohland, Lukas, Liu, Peng, Vermeulen, Bram J. A., Pfeffer, Stefan, Eustermann, Sebastian, Schiebel, Elmar
Publicado 2021

The augmin complex architecture reveals structural insights into microtubule branching

por Zupa, Erik, Würtz, Martin, Neuner, Annett, Hoffmann, Thomas, Rettel, Mandy, Böhler, Anna, Vermeulen, Bram J. A., Eustermann, Sebastian, Schiebel, Elmar, Pfeffer, Stefan
Publicado 2022

Modular assembly of the principal microtubule nucleator γ-TuRC

por Würtz, Martin, Zupa, Erik, Atorino, Enrico S., Neuner, Annett, Böhler, Anna, Rahadian, Ariani S., Vermeulen, Bram J. A., Tonon, Giulia, Eustermann, Sebastian, Schiebel, Elmar, Pfeffer, Stefan
Publicado 2022

Folding Then Binding vs Folding Through Binding in Macrocyclic Peptide Inhibitors of Human Pancreatic α-Amylase

por Goldbach, Leander, Vermeulen, Bram J. A., Caner, Sami, Liu, Minglong, Tysoe, Christina, van Gijzel, Lieke, Yoshisada, Ryoji, Trellet, Mikael, van Ingen, Hugo, Brayer, Gary D., Bonvin, Alexandre M. J. J., Jongkees, Seino A. K.
Publicado 2019

Mode of action of teixobactins in cellular membranes

por Shukla, Rhythm, Medeiros-Silva, João, Parmar, Anish, Vermeulen, Bram J. A., Das, Sanjit, Paioni, Alessandra Lucini, Jekhmane, Shehrazade, Lorent, Joseph, Bonvin, Alexandre M. J. J., Baldus, Marc, Lelli, Moreno, Veldhuizen, Edwin J. A., Breukink, Eefjan, Singh, Ishwar, Weingarth, Markus
Publicado 2020

A new antibiotic from an uncultured bacterium binds to an immutable target

por Shukla, Rhythm, Peoples, Aaron J., Ludwig, Kevin C., Maity, Sourav, Derks, Maik G.N., de Benedetti, Stefania, Krueger, Annika M, Vermeulen, Bram J.A., Lavore, Francesca, Honorato, Rodrigo V., Grein, Fabian, Bonvin, Alexandre, Kubitscheck, Ulrich, Breukink, Eefjan, Achorn, Catherine, Nitti, Anthony, Schwalen, Christopher J., Spoering, Amy L., Ling, Losee Lucy, Hughes, Dallas, Lelli, Moreno, Roos, Wouter H., Lewis, Kim, Schneider, Tanja, Weingarth, Markus
Publicado 2023

Teixobactin kills bacteria by a two-pronged attack on the cell envelope

por Shukla, Rhythm, Lavore, Francesca, Maity, Sourav, Derks, Maik G. N., Jones, Chelsea R., Vermeulen, Bram J. A., Melcrová, Adéla, Morris, Michael A., Becker, Lea Marie, Wang, Xiaoqi, Kumar, Raj, Medeiros-Silva, João, van Beekveld, Roy A. M., Bonvin, Alexandre M. J. J., Lorent, Joseph H., Lelli, Moreno, Nowick, James S., MacGillavry, Harold D., Peoples, Aaron J., Spoering, Amy L., Ling, Losee L., Hughes, Dallas E., Roos, Wouter H., Breukink, Eefjan, Lewis, Kim, Weingarth, Markus
Publicado 2022