Reversed-phase liquid chromatography coupled on-line to estrogen receptor bioaffinity detection based on fluorescence polarization

por Reinen, Jelle, Kool, Jeroen, Vermeulen, Nico P. E.
Publicado 2008

Binding free energy predictions of farnesoid X receptor (FXR) agonists using a linear interaction energy (LIE) approach with reliability estimation: application to the D3R Grand Ch...

por Rifai, Eko Aditya, van Dijk, Marc, Vermeulen, Nico P. E., Geerke, Daan P.
Publicado 2017

Characterization of kinetics of human cytochrome P450s involved in bioactivation of flucloxacillin: inhibition of CYP3A‐catalysed hydroxylation by sulfaphenazole

por Dekker, Stefan J, Dohmen, Floor, Vermeulen, Nico P E, Commandeur, Jan N M
Publicado 2018

A Comparative Linear Interaction Energy and MM/PBSA Study on SIRT1–Ligand Binding Free Energy Calculation

por Rifai, Eko Aditya, van Dijk, Marc, Vermeulen, Nico P. E., Yanuar, Arry, Geerke, Daan P.
Publicado 2019

Role of residue 87 in substrate selectivity and regioselectivity of drug-metabolizing cytochrome P450 CYP102A1 M11

por Vottero, Eduardo, Rea, Vanina, Lastdrager, Jeroen, Honing, Maarten, Vermeulen, Nico P. E., Commandeur, Jan N. M.
Publicado 2011

Acetaminophen reduces the protein levels of high affinity amino acid permeases and causes tryptophan depletion

por Huseinovic, Angelina, Dekker, Stefan J., Boogaard, Bob, Vermeulen, Nico. P. E., Kooter, Jan M., Vos, J. Chris
Publicado 2018

Improving the iterative Linear Interaction Energy approach using automated recognition of configurational transitions

por Vosmeer, C. Ruben, Kooi, Derk P., Capoferri, Luigi, Terpstra, Margreet M., Vermeulen, Nico P. E., Geerke, Daan. P.
Publicado 2016

Towards Automated Binding Affinity Prediction Using an Iterative Linear Interaction Energy Approach

por Vosmeer, C. Ruben, Pool, René, van Stee, Mariël F., Perić-Hassler, Lovorka, Vermeulen, Nico P. E., Geerke, Daan P.
Publicado 2014

Comprehensive and Automated Linear Interaction Energy Based Binding-Affinity Prediction for Multifarious Cytochrome P450 Aromatase Inhibitors

por van Dijk, Marc, ter Laak, Antonius M., Wichard, Jörg D., Capoferri, Luigi, Vermeulen, Nico P. E., Geerke, Daan P.
Publicado 2017

An on-line post-column detection system for the detection of reactive-oxygen-species-producing compounds and antioxidants in mixtures

por Kool, Jeroen, Van Liempd, Sebastiaan M., Harmsen, Stefan, Schenk, Tim, Irth, Hubertus, Commandeur, Jan N. M., Vermeulen, Nico P. E.
Publicado 2007

Application of a cocktail approach to screen cytochrome P450 BM3 libraries for metabolic activity and diversity

por Reinen, Jelle, Postma, Geert, Tump, Cornelis, Bloemberg, Tom, Engel, Jasper, Vermeulen, Nico P. E., Commandeur, Jan N. M., Honing, Maarten
Publicado 2016

Linear Interaction Energy Based Prediction of Cytochrome P450 1A2 Binding Affinities with Reliability Estimation

por Capoferri, Luigi, Verkade-Vreeker, Marlies C. A., Buitenhuis, Danny, Commandeur, Jan N. M., Pastor, Manuel, Vermeulen, Nico P. E., Geerke, Daan P.
Publicado 2015

Human multidrug resistance protein 4 (MRP4) is a cellular efflux transporter for paracetamol glutathione and cysteine conjugates

por Koenderink, Jan B., van den Heuvel, Jeroen J. M. W., Bilos, Ab, Vredenburg, Galvin, Vermeulen, Nico P. E., Russel, Frans G. M.
Publicado 2020

Free energies of binding of R- and S-propranolol to wild-type and F483A mutant cytochrome P450 2D6 from molecular dynamics simulations

por de Graaf, Chris, Oostenbrink, Chris, Keizers, Peter H. J., van Vugt-Lussenburg, Barbara M. A., Commandeur, Jan N. M., Vermeulen, Nico P. E.
Publicado 2007

The effect of acetaminophen on ubiquitin homeostasis in Saccharomyces cerevisiae

por Huseinovic, Angelina, van Leeuwen, Jolanda S., van Welsem, Tibor, Stulemeijer, Iris, van Leeuwen, Fred, Vermeulen, Nico P. E., Kooter, Jan M., Vos, J. Chris
Publicado 2017

eTOX ALLIES: an automated pipeLine for linear interaction energy-based simulations

por Capoferri, Luigi, van Dijk, Marc, Rustenburg, Ariën S., Wassenaar, Tsjerk A., Kooi, Derk P., Rifai, Eko A., Vermeulen, Nico P. E., Geerke, Daan P.
Publicado 2017

Active-site structure, binding and redox activity of the heme–thiolate enzyme CYP2D6 immobilized on coated Ag electrodes: a surface-enhanced resonance Raman scattering study

por Bonifacio, Alois, Millo, Diego, Keizers, Peter H. J., Boegschoten, Roald, Commandeur, Jan N. M., Vermeulen, Nico P. E., Gooijer, Cees, van der Zwan, Gert
Publicado 2007

Evidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in man

por Dragovic, Sanja, Vermeulen, Nico P. E., Gerets, Helga H., Hewitt, Philip G., Ingelman‐Sundberg, Magnus, Park, B. Kevin, Juhila, Satu, Snoeys, Jan, Weaver, Richard J.
Publicado 2016

Linking cytochrome P450 enzymes from Mycobacterium tuberculosis to their cognate ferredoxin partners

por Ortega Ugalde, Sandra, de Koning, Coen P., Wallraven, Kerstin, Bruyneel, Ben, Vermeulen, Nico P. E., Grossmann, Tom N., Bitter, Wilbert, Commandeur, Jan N. M., Vos, J. Chris
Publicado 2018

Glutathione S-Transferase P1 Protects Against Amodiaquine Quinoneimines-Induced Cytotoxicity but Does Not Prevent Activation of Endoplasmic Reticulum Stress in HepG2 Cells

por Zhang, Yongjie, den Braver-Sewradj, Shalenie P., den Braver, Michiel W., Hiemstra, Steven, Vermeulen, Nico P. E., van de Water, Bob, Commandeur, Jan N. M., Vos, J. C.
Publicado 2018