Novel Cannabinoid Receptor 2 (CB2) Low Lipophilicity Agonists Produce Distinct cAMP and Arrestin Signalling Kinetics without Bias

por Sharma, Raahul, Singh, Sameek, Whiting, Zak M., Molitor, Maximilian, Vernall, Andrea J., Grimsey, Natasha L.
Publicado 2023

Editorial: Therapeutic potential of the cannabinoid CB2 receptor

por Smoum, Reem, Grether, Uwe, Karsak, Meliha, Vernall, Andrea J., Park, Frank, Hillard, Cecilia J., Pacher, Pal
Publicado 2022

Fragment Screening at Adenosine-A(3) Receptors in Living Cells Using a Fluorescence-Based Binding Assay

por Stoddart, Leigh A., Vernall, Andrea J., Denman, Jessica L., Briddon, Stephen J., Kellam, Barrie, Hill, Stephen J.
Publicado 2012

Cannabinoid Receptor 2 Signalling Bias Elicited by 2,4,6-Trisubstituted 1,3,5-Triazines

por Oyagawa, Caitlin R. M., de la Harpe, Sara M., Saroz, Yurii, Glass, Michelle, Vernall, Andrea J., Grimsey, Natasha Lillia
Publicado 2018

Characterisation of AMB-FUBINACA metabolism and CB(1)-mediated activity of its acid metabolite

por Webb, Hunter D. J., Finlay, David B., Chen, Shuli, Vernall, Andrea J., Sparkes, Eric, Banister, Samuel D., Rosengren, Rhonda J., Glass, Michelle
Publicado 2022

Synthesis of novel (benzimidazolyl)isoquinolinols and evaluation as adenosine A1 receptor tools

por Singh, Sameek, Cooper, Samantha L., Glenn, Jacqueline R., Beresford, Jessica, Percival, Lydia R., Tyndall, Joel D. A., Hill, Stephen J., Kilpatrick, Laura E., Vernall, Andrea J.
Publicado 2018

Development of novel fluorescent histamine H(1)-receptor antagonists to study ligand-binding kinetics in living cells

por Stoddart, Leigh A., Vernall, Andrea J., Bouzo-Lorenzo, Monica, Bosma, Reggie, Kooistra, Albert J., de Graaf, Chris, Vischer, Henry F., Leurs, Rob, Briddon, Stephen J., Kellam, Barrie, Hill, Stephen J.
Publicado 2018