Applications of the microphysiology systems database for experimental ADME-Tox and disease models

por Schurdak, Mark, Vernetti, Lawrence, Bergenthal, Luke, Wolter, Quinn K., Shun, Tong Ying, Karcher, Sandra, Taylor, D. Lansing, Gough, Albert
Publicado 2020

Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans

por Bhushan, Abhinav, Senutovitch, Nina, Bale, Shyam S, McCarty, William J, Hegde, Manjunath, Jindal, Rohit, Golberg, Inna, Berk Usta, O, Yarmush, Martin L, Vernetti, Lawrence, Gough, Albert, Bakan, Ahmet, Shun, Tong Ying, Biasio, Richard, Lansing Taylor, D
Publicado 2013

Identifying and Quantifying Heterogeneity in High Content Analysis: Application of Heterogeneity Indices to Drug Discovery

por Gough, Albert H., Chen, Ning, Shun, Tong Ying, Lezon, Timothy R., Boltz, Robert C., Reese, Celeste E., Wagner, Jacob, Vernetti, Lawrence A., Grandis, Jennifer R., Lee, Adrian V., Stern, Andrew M., Schurdak, Mark E., Taylor, D. Lansing
Publicado 2014

The Combination of a Human Biomimetic Liver Microphysiology System with BIOLOGXsym, a Quantitative Systems Toxicology (QST) Modeling Platform for Macromolecules, Provides Mechanist...

por Beaudoin, James J., Clemens, Lara, Miedel, Mark T., Gough, Albert, Zaidi, Fatima, Ramamoorthy, Priya, Wong, Kari E., Sarangarajan, Rangaprasad, Battista, Christina, Shoda, Lisl K. M., Siler, Scott Q., Taylor, D. Lansing, Howell, Brett A., Vernetti, Lawrence A., Yang, Kyunghee
Publicado 2023

Modeling oxidative injury response in human kidney organoids

por Przepiorski, Aneta, Vanichapol, Thitinee, Espiritu, Eugenel B., Crunk, Amanda E., Parasky, Emily, McDaniels, Michael D., Emlet, Dave R., Salisbury, Ryan, Happ, Cassandra L., Vernetti, Lawrence A., MacDonald, Matthew L., Kellum, John A., Kleyman, Thomas R., Baty, Catherine J., Davidson, Alan J., Hukriede, Neil A.
Publicado 2022

A Quantitative Systems Pharmacology Platform Reveals NAFLD Pathophysiological States and Targeting Strategies

por Lefever, Daniel E., Miedel, Mark T., Pei, Fen, DiStefano, Johanna K., Debiasio, Richard, Shun, Tong Ying, Saydmohammed, Manush, Chikina, Maria, Vernetti, Lawrence A., Soto-Gutierrez, Alejandro, Monga, Satdarshan P., Bataller, Ramon, Behari, Jaideep, Yechoor, Vijay K., Bahar, Ivet, Gough, Albert, Stern, Andrew M., Taylor, D. Lansing
Publicado 2022

Biofabrication of synthetic human liver tissue with advanced programmable functions

por Florentino, Rodrigo M., Morita, Kazutoyo, Haep, Nils, Motomura, Takashi, Diaz-Aragon, Ricardo, Faccioli, Lanuza A.P., Collin de l’Hortet, Alexandra, Cetin, Zeliha, Frau, Carla, Vernetti, Lawrence, Amler, Anna-Klara, Thomas, Alexander, Lam, Tobias, Kloke, Lutz, Takeishi, Kazuki, Taylor, D. Lansing, Fox, Ira J., Soto-Gutierrez, Alejandro
Publicado 2022

Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle

por Vernetti, Lawrence, Gough, Albert, Baetz, Nicholas, Blutt, Sarah, Broughman, James R., Brown, Jacquelyn A., Foulke-Abel, Jennifer, Hasan, Nesrin, In, Julie, Kelly, Edward, Kovbasnjuk, Olga, Repper, Jonathan, Senutovitch, Nina, Stabb, Janet, Yeung, Catherine, Zachos, Nick C., Donowitz, Mark, Estes, Mary, Himmelfarb, Jonathan, Truskey, George, Wikswo, John P., Taylor, D. Lansing
Publicado 2017

Corrigendum: Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle

por Vernetti, Lawrence, Gough, Albert, Baetz, Nicholas, Blutt, Sarah, Broughman, James R., Brown, Jacquelyn A., Foulke-Abel, Jennifer, Hasan, Nesrin, In, Julie, Kelly, Edward, Kovbasnjuk, Olga, Repper, Jonathan, Senutovitch, Nina, Stabb, Janet, Yeung, Catherine, Zachos, Nick C., Donowitz, Mark, Estes, Mary, Himmelfarb, Jonathan, Truskey, George, Wikswo, John P., Taylor, D. Lansing
Publicado 2017

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis

por Argemi, Josepmaria, Latasa, Maria U., Atkinson, Stephen R., Blokhin, Ilya O., Massey, Veronica, Gue, Joel P., Cabezas, Joaquin, Lozano, Juan J., Van Booven, Derek, Bell, Aaron, Cao, Sheng, Vernetti, Lawrence A., Arab, Juan P., Ventura-Cots, Meritxell, Edmunds, Lia R., Fondevila, Constantino, Stärkel, Peter, Dubuquoy, Laurent, Louvet, Alexandre, Odena, Gemma, Gomez, Juan L., Aragon, Tomas, Altamirano, Jose, Caballeria, Juan, Jurczak, Michael J., Taylor, D. Lansing, Berasain, Carmen, Wahlestedt, Claes, Monga, Satdarshan P., Morgan, Marsha Y., Sancho-Bru, Pau, Mathurin, Philippe, Furuya, Shinji, Lackner, Carolin, Rusyn, Ivan, Shah, Vijay H., Thursz, Mark R., Mann, Jelena, Avila, Matias A., Bataller, Ramon
Publicado 2019

Author Correction: Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis

por Argemi, Josepmaria, Latasa, Maria U., Atkinson, Stephen R., Blokhin, Ilya O., Massey, Veronica, Gue, Joel P., Cabezas, Joaquin, Lozano, Juan J., Van Booven, Derek, Bell, Aaron, Cao, Sheng, Vernetti, Lawrence A., Arab, Juan P., Ventura-Cots, Meritxell, Edmunds, Lia R., Fondevila, Constantino, Stärkel, Peter, Dubuquoy, Laurent, Louvet, Alexandre, Odena, Gemma, Gomez, Juan L., Aragon, Tomas, Altamirano, Jose, Caballeria, Juan, Jurczak, Michael J., Taylor, D. Lansing, Berasain, Carmen, Wahlestedt, Claes, Monga, Satdarshan P., Morgan, Marsha Y., Sancho-Bru, Pau, Mathurin, Philippe, Furuya, Shinji, Lackner, Carolin, Rusyn, Ivan, Shah, Vijay H., Thursz, Mark R., Mann, Jelena, Avila, Matias A., Bataller, Ramon
Publicado 2023