Protein phosphatase 2A (PP2A): a key phosphatase in the progression of chronic obstructive pulmonary disease (COPD) to lung cancer

por Nader, Cassandra P., Cidem, Aylin, Verrills, Nicole M., Ammit, Alaina J.
Publicado 2019

A systematic evaluation of the safety and toxicity of fingolimod for its potential use in the treatment of acute myeloid leukaemia

por Enjeti, Anoop K., D’Crus, Angel, Melville, Kathleen, Verrills, Nicole M., Rowlings, Philip
Publicado 2016

Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development

por Panicker, Nikita, Coutman, Melody, Lawlor-O’Neill, Charley, Kahl, Richard G. S., Roselli, Séverine, Verrills, Nicole M.
Publicado 2020

Basal protein phosphatase 2A activity restrains cytokine expression: role for MAPKs and tristetraprolin

por Rahman, Md. Mostafizur, Rumzhum, Nowshin N., Morris, Jonathan C., Clark, Andrew R., Verrills, Nicole M., Ammit, Alaina J.
Publicado 2015

Cell‐Free DNA Blood Collection Tubes Are Appropriate for Clinical Proteomics: A Demonstration in Colorectal Cancer

por Almazi, Juhura G., Pockney, Peter, Gedye, Craig, Smith, Nathan D., Hondermarck, Hubert, Verrills, Nicole M., Dun, Matthew D.
Publicado 2018

Targeting Oncogenic Signaling in Mutant FLT3 Acute Myeloid Leukemia: The Path to Least Resistance

por Staudt, Dilana, Murray, Heather C., McLachlan, Tabitha, Alvaro, Frank, Enjeti, Anoop K., Verrills, Nicole M., Dun, Matthew D.
Publicado 2018

Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons

por Goldie, Belinda J., Dun, Matthew D., Lin, Minjie, Smith, Nathan D., Verrills, Nicole M., Dayas, Christopher V., Cairns, Murray J.
Publicado 2014

Synergistic Targeting of DNA-PK and KIT Signaling Pathways in KIT Mutant Acute Myeloid Leukemia

por Murray, Heather C., Miller, Kasey, Brzozowski, Joshua S., Kahl, Richard G.S., Smith, Nathan D., Humphrey, Sean J., Dun, Matthew D., Verrills, Nicole M.
Publicado 2023

scTEM-seq: Single-cell analysis of transposable element methylation to link global epigenetic heterogeneity with transcriptional programs

por Hunt, Kooper V., Burnard, Sean M., Roper, Ellise A., Bond, Danielle R., Dun, Matthew D., Verrills, Nicole M., Enjeti, Anoop K., Lee, Heather J.
Publicado 2022

The phosphorylated form of FTY720 activates PP2A, represses inflammation and is devoid of S1P agonism in A549 lung epithelial cells

por Rahman, Md. Mostafizur, Prünte, Laura, Lebender, Leonard F., Patel, Brijeshkumar S., Gelissen, Ingrid, Hansbro, Philip M., Morris, Jonathan C., Clark, Andrew R., Verrills, Nicole M., Ammit, Alaina J.
Publicado 2016

Expression of renin–angiotensin system (RAS) components in endometrial cancer

por Delforce, Sarah J, Lumbers, Eugenie R, Corbisier de Meaultsart, Celine, Wang, Yu, Proietto, Anthony, Otton, Geoffrey, Scurry, Jim, Verrills, Nicole M, Scott, Rodney J, Pringle, Kirsty G
Publicado 2016

Role of the prorenin receptor in endometrial cancer cell growth

por Martin, Jacinta H., Mohammed, Riazuddin, Delforce, Sarah J., Skerrett-Byrne, David A., de Meaultsart, Celine Corbisier, Almazi, Juhura G., Stephens, Andrew N., Verrills, Nicole M., Dimitriadis, Evdokia, Wang, Yu, Lumbers, Eugenie R., Pringle, Kirsty G.
Publicado 2022

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors

por Smith, Amanda M., Dun, Matthew D., Lee, Erwin M., Harrison, Celeste, Kahl, Richard, Flanagan, Hayley, Panicker, Nikita, Mashkani, Baratali, Don, Anthony S., Morris, Jonathan, Toop, Hamish, Lock, Richard B., Powell, Jason A., Thomas, Daniel, Guthridge, Mark A., Moore, Andrew, Ashman, Leonie K., Skelding, Kathryn A., Enjeti, Anoop, Verrills, Nicole M.
Publicado 2016

Quantitative phosphoproteomics uncovers synergy between DNA-PK and FLT3 inhibitors in acute myeloid leukaemia

por Murray, Heather C., Enjeti, Anoop K., Kahl, Richard G. S., Flanagan, Hayley M., Sillar, Jonathan, Skerrett-Byrne, David A., Al Mazi, Juhura G., Au, Gough G., de Bock, Charles E., Evans, Kathryn, Smith, Nathan D., Anderson, Amanda, Nixon, Brett, Lock, Richard B., Larsen, Martin R., Verrills, Nicole M., Dun, Matthew D.
Publicado 2020

Correction to: Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection

por Staudt, Dilana E., Murray, Heather C., Skerrett-Byrne, David A., Smith, Nathan D., Jamaluddin, M. Fairuz B., Kahl, Richard G. S., Duchatel, Ryan J., Germon, Zacary P., McLachlan, Tabitha, Jackson, Evangeline R., Findlay, Izac J., Kearney, Padraic S., Mannan, Abdul, McEwen, Holly P., Douglas, Alicia M., Nixon, Brett, Verrills, Nicole M., Dun, Matthew D.
Publicado 2023

Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection

por Staudt, Dilana E., Murray, Heather C., Skerrett-Byrne, David A., Smith, Nathan D., Jamaluddin, M. Fairuz B., Kahl, Richard G. S., Duchatel, Ryan J., Germon, Zacary P., McLachlan, Tabitha, Jackson, Evangeline R., Findlay, Izac J., Kearney, Padraic S., Mannan, Abdul, McEwen, Holly P., Douglas, Alicia M., Nixon, Brett, Verrills, Nicole M., Dun, Matthew D.
Publicado 2022

Shwachman–Bodian–Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia

por Dun, Matthew D., Mannan, Abdul, Rigby, Callum J., Butler, Stephen, Toop, Hamish D., Beck, Dominik, Connerty, Patrick, Sillar, Jonathan, Kahl, Richard G. S., Duchatel, Ryan J., Germon, Zacary, Faulkner, Sam, Chi, Mengna, Skerrett-Byrne, David, Murray, Heather C., Flanagan, Hayley, Almazi, Juhura G., Hondermarck, Hubert, Nixon, Brett, De Iuliis, Geoff, Chamberlain, Janis, Alvaro, Frank, de Bock, Charles E., Morris, Jonathan C., Enjeti, Anoop K., Verrills, Nicole M.
Publicado 2020