Uncovering Ubiquitin and Ubiquitin-like Signaling Networks

por Vertegaal, Alfred C. O.
Publicado 2011

Mapping the SUMOylated landscape

por Eifler, Karolin, Vertegaal, Alfred C.O.
Publicado 2015

Ubiquitin-dependent and independent roles of SUMO in proteostasis

por Liebelt, Frauke, Vertegaal, Alfred C. O.
Publicado 2016

SUMO in the DNA damage response

por Hendriks, Ivo A., Vertegaal, Alfred C.O.
Publicado 2015

Converging Small Ubiquitin-like Modifier (SUMO) and Ubiquitin Signaling: Improved Methodology Identifies Co-modified Target Proteins

por Cuijpers, Sabine A. G., Willemstein, Edwin, Vertegaal, Alfred C. O.
Publicado 2017

Chemical Tools and Biochemical Assays for SUMO Specific Proteases (SENPs)

por Jia, Yuqing, Claessens, Laura A., Vertegaal, Alfred C. O., Ovaa, Huib
Publicado 2019

RNF4 and VHL regulate the proteasomal degradation of SUMO-conjugated Hypoxia-Inducible Factor-2α

por van Hagen, Martijn, Overmeer, René M., Abolvardi, Sharareh S., Vertegaal, Alfred C. O.
Publicado 2010

Inhibiting ubiquitination causes an accumulation of SUMOylated newly synthesized nuclear proteins at PML bodies

por Sha, Zhe, Blyszcz, Tamara, González-Prieto, Román, Vertegaal, Alfred C. O., Goldberg, Alfred L.
Publicado 2019

SENP6 regulates localization and nuclear condensation of DNA damage response proteins by group deSUMOylation

por Claessens, Laura A., Verlaan-de Vries, Matty, de Graaf, Ilona J., Vertegaal, Alfred C. O.
Publicado 2023

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery

por Kumar, Ramesh, González-Prieto, Román, Xiao, Zhenyu, Verlaan-de Vries, Matty, Vertegaal, Alfred C. O.
Publicado 2017

System-wide identification of wild-type SUMO-2 conjugation sites

por Hendriks, Ivo A., D'Souza, Rochelle C., Chang, Jer-Gung, Mann, Matthias, Vertegaal, Alfred C. O.
Publicado 2015

Uncovering Global SUMOylation Signaling Networks in a Site-Specific Manner

por Hendriks, Ivo A., D’Souza, Rochelle C.J., Yang, Bing, Verlaan-de Vries, Matty, Mann, Matthias, Vertegaal, Alfred C.O.
Publicado 2014

Chromokinesin KIF4A teams up with stathmin 1 to regulate abscission in a SUMO-dependent manner

por Cuijpers, Sabine A. G., Willemstein, Edwin, Ruppert, Jan G., van Elsland, Daphne M., Earnshaw, William C., Vertegaal, Alfred C. O.
Publicado 2020

SUMOylation and the HSF1-Regulated Chaperone Network Converge to Promote Proteostasis in Response to Heat Shock

por Liebelt, Frauke, Sebastian, Rebecca M., Moore, Christopher L., Mulder, Monique P.C., Ovaa, Huib, Shoulders, Matthew D., Vertegaal, Alfred C.O.
Publicado 2019

The poly-SUMO2/3 protease SENP6 enables assembly of the constitutive centromere-associated network by group deSUMOylation

por Liebelt, Frauke, Jansen, Nicolette S., Kumar, Sumit, Gracheva, Ekaterina, Claessens, Laura A., Verlaan-de Vries, Matty, Willemstein, Edwin, Vertegaal, Alfred C. O.
Publicado 2019

In‐Plate Chemical Synthesis of Isopeptide‐Linked SUMOylated Peptide Fluorescence Polarization Reagents for High‐Throughput Screening of SENP Preferences

por Huppelschoten, Yara, Mukhopadhyay, Rishov, Buchardt, Jens, Nielsen, Thomas E., Vertegaal, Alfred C. O., Ovaa, Huib, van der Heden van Noort, Gerbrand J.
Publicado 2022

SUMOylation Is Associated with Aggressive Behavior in Chondrosarcoma of Bone

por Kroonen, Jessie S., Kruisselbrink, Alwine B., Briaire-de Bruijn, Inge H., Olaofe, Olaejirinde O., Bovée, Judith V. M. G., Vertegaal, Alfred C. O.
Publicado 2021

Inhibition of SUMOylation enhances DNA hypomethylating drug efficacy to reduce outgrowth of hematopoietic malignancies

por Kroonen, Jessie S., de Graaf, Ilona J., Kumar, Sumit, Remst, Dennis F. G., Wouters, Anne K., Heemskerk, Mirjam H. M., Vertegaal, Alfred C. O.
Publicado 2023

SUMO targets the APC/C to regulate transition from metaphase to anaphase

por Eifler, Karolin, Cuijpers, Sabine A. G., Willemstein, Edwin, Raaijmakers, Jonne A., El Atmioui, Dris, Ovaa, Huib, Medema, René H., Vertegaal, Alfred C. O.
Publicado 2018

Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation

por Yatskevich, Stanislau, Kroonen, Jessie S., Alfieri, Claudio, Tischer, Thomas, Howes, Anna C., Clijsters, Linda, Yang, Jing, Zhang, Ziguo, Yan, Kaige, Vertegaal, Alfred C.O., Barford, David
Publicado 2021