Dysregulation of mTOR activity through LKB1 inactivation

por Zhou, Wei, Marcus, Adam I., Vertino, Paula M.
Publicado 2013

GC skew defines distinct RNA polymerase pause sites in CpG island promoters

por Kellner, Wendy A., Bell, Joshua S.K., Vertino, Paula M.
Publicado 2015

Cell of Origin and Genetic Alterations in the Pathogenesis of Multiple Myeloma

por Barwick, Benjamin G., Gupta, Vikas A., Vertino, Paula M., Boise, Lawrence H.
Publicado 2019

Subtype-Independent ANP32E Reduction During Breast Cancer Progression in Accordance with Chromatin Relaxation

por Ruff, Garrett L., Murphy, Kristin E., Smith, Zachary R., Vertino, Paula M., Murphy, Patrick J.
Publicado 2021

Small molecule inhibition of the CHFR-PARP1 interaction as novel approach to overcome intrinsic taxane resistance in cancer

por Brodie, Seth A., Li, Ge, Harvey, Donald, Khuri, Fadlo R., Vertino, Paula M., Brandes, Johann C.
Publicado 2015

A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer

por Scott, Emma C., Gardner, Eugene J., Masood, Ashiq, Chuang, Nelson T., Vertino, Paula M., Devine, Scott E.
Publicado 2016

Withania somnifera Root Extract Inhibits Mammary Cancer Metastasis and Epithelial to Mesenchymal Transition

por Yang, Zhen, Garcia, Anapatricia, Xu, Songli, Powell, Doris R., Vertino, Paula M., Singh, Shivendra, Marcus, Adam I.
Publicado 2013

Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation

por Hashimoto, Hideharu, Liu, Yiwei, Upadhyay, Anup K., Chang, Yanqi, Howerton, Shelley B., Vertino, Paula M., Zhang, Xing, Cheng, Xiaodong
Publicado 2012

MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma

por Wang, Dongxue, Hashimoto, Hideharu, Zhang, Xing, Barwick, Benjamin G., Lonial, Sagar, Boise, Lawrence H., Vertino, Paula M., Cheng, Xiaodong
Publicado 2017

Aberrant Hypermethylation-Mediated Suppression of PYCARD Is Extremely Frequent in Prostate Cancer with Gleason Score ≥ 7

por Miyauchi, Toshiya, Takahashi, Masahiro, Mitsuzuka, Koji, Saiki, Yuriko, Okubo, Teppei, Vertino, Paula M., Goto, Akiteru, Arai, Yoichi, Horii, Akira, Fukushige, Shinichi
Publicado 2021

CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

por Lin, Yanni, Cradick, Thomas J., Brown, Matthew T., Deshmukh, Harshavardhan, Ranjan, Piyush, Sarode, Neha, Wile, Brian M., Vertino, Paula M., Stewart, Frank J., Bao, Gang
Publicado 2014

Aberrant Promoter Methylation of Caveolin-1 Is Associated with Favorable Response to Taxane-Platinum Combination Chemotherapy in Advanced NSCLC

por Brodie, Seth A., Lombardo, Courtney, Li, Ge, Kowalski, Jeanne, Gandhi, Khanjan, You, Shaojin, Khuri, Fadlo R., Marcus, Adam, Vertino, Paula M., Brandes, Johann C.
Publicado 2014

A heterozygous IDH1(R132H/WT) mutation induces genome-wide alterations in DNA methylation

por Duncan, Christopher G., Barwick, Benjamin G., Jin, Genglin, Rago, Carlo, Kapoor-Vazirani, Priya, Powell, Doris R., Chi, Jen-Tsan, Bigner, Darell D., Vertino, Paula M., Yan, Hai
Publicado 2012

Integrated Analysis of Whole-Genome Paired-End and Mate-Pair Sequencing Data for Identifying Genomic Structural Variations in Multiple Myeloma

por Yang, Rendong, Chen, Li, Newman, Scott, Gandhi, Khanjan, Doho, Gregory, Moreno, Carlos S, Vertino, Paula M, Bernal-Mizarchi, Leon, Lonial, Sagar, Boise, Lawrence H, Rossi, Michael, Kowalski, Jeanne, Qin, Zhaohui S
Publicado 2014

Chronic liver inflammation modifies DNA methylation at the precancerous stage of murine hepatocarcinogenesis

por Stoyanov, Evgeniy, Ludwig, Guy, Mizrahi, Lina, Olam, Devorah, Schnitzer-Perlman, Temima, Tasika, Elena, Sass, Gabriele, Tiegs, Gisa, Jiang, Yong, Nie, Ting, Kohler, James, Schinazi, Raymond F., Vertino, Paula M., Cedar, Howard, Galun, Eithan, Goldenberg, Daniel
Publicado 2015

Multiple myeloma immunoglobulin lambda translocations portend poor prognosis

por Barwick, Benjamin G., Neri, Paola, Bahlis, Nizar J., Nooka, Ajay K., Dhodapkar, Madhav V., Jaye, David L., Hofmeister, Craig C., Kaufman, Jonathan L., Gupta, Vikas A., Auclair, Daniel, Keats, Jonathan J., Lonial, Sagar, Vertino, Paula M., Boise, Lawrence H.
Publicado 2019

Epigenetically heterogeneous tumor cells direct collective invasion through filopodia-driven fibronectin micropatterning

por Summerbell, Emily R., Mouw, Janna K., Bell, Joshua S. K., Knippler, Christina M., Pedro, Brian, Arnst, Jamie L., Khatib, Tala O., Commander, Rachel, Barwick, Benjamin G., Konen, Jessica, Dwivedi, Bhakti, Seby, Sandra, Kowalski, Jeanne, Vertino, Paula M., Marcus, Adam I.
Publicado 2020

Gene integrated set profile analysis: a context-based approach for inferring biological endpoints

por Kowalski, Jeanne, Dwivedi, Bhakti, Newman, Scott, Switchenko, Jeffery M., Pauly, Rini, Gutman, David A., Arora, Jyoti, Gandhi, Khanjan, Ainslie, Kylie, Doho, Gregory, Qin, Zhaohui, Moreno, Carlos S., Rossi, Michael R., Vertino, Paula M., Lonial, Sagar, Bernal-Mizrachi, Leon, Boise, Lawrence H.
Publicado 2016

Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma

por Guo, Bing, Friedland, Scott C., Alexander, William, Myers, Jacquelyn A., Wang, Wenjia, O’Dell, Michael R., Getman, Michael, Whitney-Miller, Christa L., Agostini-Vulaj, Diana, Huber, Aaron R., Mello, Stephano S., Vertino, Paula M., Land, Hartmut K., Steiner, Laurie A., Hezel, Aram F.
Publicado 2022

Acetylation of KLF5 maintains EMT and tumorigenicity to cause chemoresistant bone metastasis in prostate cancer

por Zhang, Baotong, Li, Yixiang, Wu, Qiao, Xie, Lin, Barwick, Benjamin, Fu, Changying, Li, Xin, Wu, Daqing, Xia, Siyuan, Chen, Jing, Qian, Wei Ping, Yang, Lily, Osunkoya, Adeboye O., Boise, Lawrence, Vertino, Paula M., Zhao, Yichao, Li, Menglin, Chen, Hsiao-Rong, Kowalski, Jeanne, Kucuk, Omer, Zhou, Wei, Dong, Jin-Tang
Publicado 2021