Dynamic RNA Polymerase II Recruitment Drives Differentiation of the Intestine under the direction of HNF4

por Vemuri, Kiranmayi, Kumar, Sneha, Chen, Lei, Verzi, Michael P.
Publicado 2023

Multiple roles and regulatory mechanisms of the transcription factor HNF4 in the intestine

por Vemuri, Kiranmayi, Radi, Sarah H., Sladek, Frances M., Verzi, Michael P.
Publicado 2023

Control of Cell Identity by the Nuclear Receptor HNF4 in Organ Pathophysiology

por Dubois, Vanessa, Staels, Bart, Lefebvre, Philippe, Verzi, Michael P., Eeckhoute, Jérôme
Publicado 2020

Moringa isothiocyanate-1 regulates Nrf2 and NF-κB pathway in response to LPS-driven sepsis and inflammation

por Sailaja, Badi Sri, Aita, Rohit, Maledatu, Shane, Ribnicky, David, Verzi, Michael P., Raskin, Ilya
Publicado 2021

Moringa isothiocyanate-1 inhibits LPS-induced inflammation in mouse myoblasts and skeletal muscle

por Sailaja, Badi Sri, Hassan, Sohaib, Cohen, Evan, Tmenova, Irina, Farias-Pereira, Renalison, Verzi, Michael P., Raskin, Ilya
Publicado 2022

Isothiocyanate-enriched moringa seed extract alleviates ulcerative colitis symptoms in mice

por Kim, Youjin, Wu, Alex G., Jaja-Chimedza, Asha, Graf, Brittany L., Waterman, Carrie, Verzi, Michael P., Raskin, Ilya
Publicado 2017

A reinforcing HNF4-SMAD4 feed-forward module stabilizes enterocyte identity

por Chen, Lei, Toke, Natalie H., Luo, Shirley, Vasoya, Roshan P., Fullem, Robert L., Parthasarathy, Aditya, Perekatt, Ansu O., Verzi, Michael P.
Publicado 2019

Three-dimensional interactions between enhancers and promoters during intestinal differentiation depend upon HNF4

por Chen, Lei, Cao, Weihuan, Aita, Rohit, Aldea, Dennis, Flores, Juan, Gao, Nan, Bonder, Edward M., Ellison, Christopher E., Verzi, Michael P.
Publicado 2021

LGR4 and LGR5 Function Redundantly During Human Endoderm Differentiation

por Tsai, Yu-Hwai, Hill, David R., Kumar, Namit, Huang, Sha, Chin, Alana M., Dye, Briana R., Nagy, Melinda S., Verzi, Michael P., Spence, Jason R.
Publicado 2016

Genomic analysis of 1,25-dihydroxyvitamin D(3) action in mouse intestine reveals compartment and segment-specific gene regulatory effects

por Aita, Rohit, Aldea, Dennis, Hassan, Sohaib, Hur, Joseph, Pellon-Cardenas, Oscar, Cohen, Evan, Chen, Lei, Shroyer, Noah, Christakos, Sylvia, Verzi, Michael P., Fleet, James C.
Publicado 2022

TGFB1 Induces Fetal Reprogramming and Enhances Intestinal Regeneration

por Chen, Lei, Dupre, Abigail, Qiu, Xia, Pellon-Cardenas, Oscar, Walton, Katherine D., Wang, Jianming, Perekatt, Ansu O., Hu, Wenwei, Spence, Jason R., Verzi, Michael P.
Publicado 2023

SOX4 and SMARCA4 cooperatively regulate PI3k signaling through transcriptional activation of TGFBR2

por Mehta, Gaurav A., Angus, Steven P., Khella, Christen A., Tong, Kevin, Khanna, Pooja, Dixon, Shelley A. H., Verzi, Michael P., Johnson, Gary L., Gatza, Michael L.
Publicado 2021

FILIP1L Loss Is a Driver of Aggressive Mucinous Colorectal Adenocarcinoma and Mediates Cytokinesis Defects through PFDN1

por Kwon, Mijung, Rubio, Genesaret, Nolan, Nicholas, Auteri, Peter, Volmar, Jean Arly, Adem, Asha, Javidian, Parisa, Zhou, Zhongren, Verzi, Michael P., Pine, Sharon R., Libutti, Steven K.
Publicado 2021

Enhancer, transcriptional, and cell fate plasticity precedes intestinal determination during endoderm development

por Banerjee, Kushal K., Saxena, Madhurima, Kumar, Namit, Chen, Lei, Cavazza, Alessia, Toke, Natalie H., O'Neill, Nicholas K., Madha, Shariq, Jadhav, Unmesh, Verzi, Michael P., Shivdasani, Ramesh A.
Publicado 2018

LIN28B induces a differentiation program through CDX2 in colon cancer

por Suzuki, Kensuke, Masuike, Yasunori, Mizuno, Rei, Sachdeva, Uma M., Chatterji, Priya, Andres, Sarah F., Sun, Wenping, Klein-Szanto, Andres J., Besharati, Sepideh, Remotti, Helen E., Verzi, Michael P., Rustgi, Anil K.
Publicado 2021

SIRT7 mediates L1 elements transcriptional repression and their association with the nuclear lamina

por Vazquez, Berta N, Thackray, Joshua K, Simonet, Nicolas G, Chahar, Sanjay, Kane-Goldsmith, Noriko, Newkirk, Simon J, Lee, Suman, Xing, Jinchuan, Verzi, Michael P, An, Wenfeng, Vaquero, Alejandro, Tischfield, Jay A, Serrano, Lourdes
Publicado 2019

SMAD4 is Critical in Suppression of BRAF-V600E Serrated Tumorigenesis

por Tong, Kevin, Kothari, Om A., Haro, Katherine S., Panda, Anshuman, Bandari, Manisha M., Carrick, Jillian N., Hur, Joseph J., Zhang, Lanjing, Chan, Chang S., Xing, Jinchuan, Gatza, Michael L., Ganesan, Shridar, Verzi, Michael P.
Publicado 2021

RAB11A and RAB11B control mitotic spindle function in intestinal epithelial progenitor cells

por Joseph, Ivor, Flores, Juan, Farrell, Victoria, Davis, Justin, Bianchi‐Smak, Jared, Feng, Qiang, Goswami, Sayantani, Lin, Xiang, Wei, Zhi, Tong, Kevin, Feng, Zhaohui, Verzi, Michael P, Bonder, Edward M, Goldenring, James R, Gao, Nan
Publicado 2023

Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche

por Das, Soumyashree, Yu, Shiyan, Sakamori, Ryotaro, Vedula, Pavan, Feng, Qiang, Flores, Juan, Hoffman, Andrew, Fu, Jiang, Stypulkowski, Ewa, Rodriguez, Alexis, Dobrowolski, Radek, Harada, Akihiro, Hsu, Wei, Bonder, Edward M., Verzi, Michael P., Gao, Nan
Publicado 2015

Optical High Content Nanoscopy of Epigenetic Marks Decodes Phenotypic Divergence in Stem Cells

por Kim, Joseph J., Bennett, Neal K., Devita, Mitchel S., Chahar, Sanjay, Viswanath, Satish, Lee, Eunjee A., Jung, Giyoung, Shao, Paul P., Childers, Erin P., Liu, Shichong, Kulesa, Anthony, Garcia, Benjamin A., Becker, Matthew L., Hwang, Nathaniel S., Madabhushi, Anant, Verzi, Michael P., Moghe, Prabhas V.
Publicado 2017