Rethinking growth factors: the case of BMP9 during vessel maturation

por Medina-Jover, Ferran, Riera-Mestre, Antoni, Viñals, Francesc
Publicado 2022

The impact of KRAS mutations on VEGF-A production and tumour vascular network

por Figueras, Agnès, Arbos, Maria Antonia, Quiles, Maria Teresa, Viñals, Francesc, Germà, Josep Ramón, Capellà, Gabriel
Publicado 2013

PI3K (Phosphatidylinositol 3-Kinase) Activation and Endothelial Cell Proliferation in Patients with Hemorrhagic Hereditary Telangiectasia Type 1

por Iriarte, Adriana, Figueras, Agnes, Cerdà, Pau, Mora, José María, Jucglà, Anna, Penín, Rosa, Viñals, Francesc, Riera-Mestre, Antoni
Publicado 2019

Regulation of the MDM2‐p53 pathway by the ubiquitin ligase HERC2

por García‐Cano, Jesús, Sánchez‐Tena, Susana, Sala‐Gaston, Joan, Figueras, Agnès, Viñals, Francesc, Bartrons, Ramon, Ventura, Francesc, Rosa, Jose Luis
Publicado 2019

Glycosylation defects, offset by PEPCK-M, drive entosis in breast carcinoma cells

por Hyroššová, Petra, Aragó, Marc, Muñoz-Pinedo, Cristina, Viñals, Francesc, García-Rovés, Pablo M., Escolano, Carmen, Méndez-Lucas, Andrés, Perales, Jose C.
Publicado 2022

Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis

por Soler, Adriana, Serra, Helena, Pearce, Wayne, Angulo, Ana, Guillermet-Guibert, Julie, Friedman, Lori S., Viñals, Francesc, Gerhardt, Holger, Casanovas, Oriol, Graupera, Mariona, Vanhaesebroeck, Bart
Publicado 2013

Effectivity of pazopanib treatment in orthotopic models of human testicular germ cell tumors

por Juliachs, Mercè, Vidal, August, del Muro, Xavier Garcia, Piulats, Josep M, Condom, Enric, Casanovas, Oriol, Graupera, Mariona, Germà, Jose R, Villanueva, Alberto, Viñals, Francesc
Publicado 2013

PEPCK-M recoups tumor cell anabolic potential in a PKC-ζ-dependent manner

por Hyroššová, Petra, Aragó, Marc, Moreno-Felici, Juan, Fu, Xiarong, Mendez-Lucas, Andrés, García-Rovés, Pablo M., Burgess, Shawn, Figueras, Agnès, Viñals, Francesc, Perales, Jose C.
Publicado 2021

TGFβ Controls Ovarian Cancer Cell Proliferation

por Alsina-Sanchís, Elisenda, Figueras, Agnès, Lahiguera, Alvaro, Gil-Martín, Marta, Pardo, Beatriz, Piulats, Josep M., Martí, Lola, Ponce, Jordi, Matias-Guiu, Xavier, Vidal, August, Villanueva, Alberto, Viñals, Francesc
Publicado 2017

Resistance to Antiangiogenic Therapies by Metabolic Symbiosis in Renal Cell Carcinoma PDX Models and Patients

por Jiménez-Valerio, Gabriela, Martínez-Lozano, Mar, Bassani, Nicklas, Vidal, August, Ochoa-de-Olza, María, Suárez, Cristina, García-del-Muro, Xavier, Carles, Joan, Viñals, Francesc, Graupera, Mariona, Indraccolo, Stefano, Casanovas, Oriol
Publicado 2016

The pancreatic niche inhibits the effectiveness of sunitinib treatment of pancreatic cancer

por Martínez-Bosch, Neus, Guerrero, Pedro Enrique, Moreno, Mireia, José, Anabel, Iglesias, Mar, Munné-Collado, Jessica, Anta, Héctor, Gibert, Joan, Orozco, Carlos Alberto, Vinaixa, Judith, Fillat, Cristina, Viñals, Francesc, Navarro, Pilar
Publicado 2016

Phase II study of preoperative bevacizumab, capecitabine and radiotherapy for resectable locally-advanced rectal cancer

por García, Margarita, Martinez-Villacampa, Mercedes, Santos, Cristina, Navarro, Valentin, Teule, Alex, Losa, Ferran, Pisa, Aleydis, Cambray, Maria, Soler, Gemma, Lema, Laura, Kreisler, Esther, Figueras, Agnes, Juan, Xavier San, Viñals, Francesc, Biondo, Sebastiano, Salazar, Ramon
Publicado 2015

PDGFR-induced autocrine SDF-1 signaling in cancer cells promotes metastasis in advanced skin carcinoma

por Bernat-Peguera, Adrià, Simón-Extremera, Pilar, da Silva-Diz, Victoria, López de Munain, Mikel, Díaz-Gil, Laura, Penin, Rosa M., González-Suárez, Eva, Pérez Sidelnikova, Diana, Bermejo, Oriol, Viñals, Joan Maria, Viñals, Francesc, Muñoz, Purificación
Publicado 2019

PTEN mediates Notch-dependent stalk cell arrest in angiogenesis

por Serra, Helena, Chivite, Iñigo, Angulo-Urarte, Ana, Soler, Adriana, Sutherland, James D., Arruabarrena-Aristorena, Amaia, Ragab, Anan, Lim, Radiance, Malumbres, Marcos, Fruttiger, Marcus, Potente, Michael, Serrano, Manuel, Fabra, Àngels, Viñals, Francesc, Casanovas, Oriol, Pandolfi, Pier Paolo, Bigas, Anna, Carracedo, Arkaitz, Gerhardt, Holger, Graupera, Mariona
Publicado 2015

Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility

por Angulo-Urarte, Ana, Casado, Pedro, Castillo, Sandra D., Kobialka, Piotr, Kotini, Maria Paraskevi, Figueiredo, Ana M., Castel, Pau, Rajeeve, Vinothini, Milà-Guasch, Maria, Millan, Jaime, Wiesner, Cora, Serra, Helena, Muixi, Laia, Casanovas, Oriol, Viñals, Francesc, Affolter, Markus, Gerhardt, Holger, Huveneers, Stephan, Belting, Heinz-Georg, Cutillas, Pedro R., Graupera, Mariona
Publicado 2018

Tumors defective in homologous recombination rely on oxidative metabolism: relevance to treatments with PARP inhibitors

por Lahiguera, Álvaro, Hyroššová, Petra, Figueras, Agnès, Garzón, Diana, Moreno, Roger, Soto‐Cerrato, Vanessa, McNeish, Iain, Serra, Violeta, Lazaro, Conxi, Barretina, Pilar, Brunet, Joan, Menéndez, Javier, Matias‐Guiu, Xavier, Vidal, August, Villanueva, Alberto, Taylor‐Harding, Barbie, Tanaka, Hisashi, Orsulic, Sandra, Junza, Alexandra, Yanes, Oscar, Muñoz‐Pinedo, Cristina, Palomero, Luís, Pujana, Miquel Àngel, Perales, José Carlos, Viñals, Francesc
Publicado 2020

Generation and Integrated Analysis of Advanced Patient‐Derived Orthoxenograft Models (PDOX) for the Rational Assessment of Targeted Therapies in Endometrial Cancer

por Devis‐Jauregui, Laura, Vidal, August, Plata‐Peña, Laura, Santacana, Maria, García‐Mulero, Sandra, Bonifaci, Nuria, Noguera‐Delgado, Eulàlia, Ruiz, Nuria, Gil, Marta, Dorca, Eduard, Llobet, Francisco J., Coll‐Iglesias, Laura, Gassner, Katja, Martinez‐Iniesta, Maria, Rodriguez‐Barrueco, Ruth, Barahona, Marc, Marti, Lola, Viñals, Francesc, Ponce, Jordi, Sanz‐Pamplona, Rebeca, Piulats, Josep M., Vivancos, Ana, Matias‐Guiu, Xavier, Villanueva, Alberto, Llobet‐Navas, David
Publicado 2022

CDK-mediated activation of the SCF(FBXO28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer

por Cepeda, Diana, Ng, Hwee-Fang, Sharifi, Hamid Reza, Mahmoudi, Salah, Cerrato, Vanessa Soto, Fredlund, Erik, Magnusson, Kristina, Nilsson, Helén, Malyukova, Alena, Rantala, Juha, Klevebring, Daniel, Viñals, Francesc, Bhaskaran, Nimesh, Zakaria, Siti Mariam, Rahmanto, Aldwin Suryo, Grotegut, Stefan, Nielsen, Michael Lund, Szigyarto, Cristina Al-Khalili, Sun, Dahui, Lerner, Mikael, Navani, Sanjay, Widschwendter, Martin, Uhlén, Mathias, Jirström, Karin, Pontén, Fredrik, Wohlschlegel, James, Grandér, Dan, Spruck, Charles, Larsson, Lars-Gunnar, Sangfelt, Olle
Publicado 2013

A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect

por Lopez-Serra, Paula, Marcilla, Miguel, Villanueva, Alberto, Ramos-Fernandez, Antonio, Palau, Anna, Leal, Lucía, Wahi, Jessica E., Setien-Baranda, Fernando, Szczesna, Karolina, Moutinho, Catia, Martinez-Cardus, Anna, Heyn, Holger, Sandoval, Juan, Puertas, Sara, Vidal, August, Sanjuan, Xavier, Martinez-Balibrea, Eva, Viñals, Francesc, Perales, Jose C., Bramsem, Jesper B., Ørntoft, Torben F., Andersen, Claus L., Tabernero, Josep, McDermott, Ultan, Boxer, Matthew B., Heiden, Matthew G. Vander, Albar, Juan Pablo, Esteller, Manel
Publicado 2014

Corrigendum: A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect

por Lopez-Serra, Paula, Marcilla, Miguel, Villanueva, Alberto, Ramos-Fernandez, Antonio, Palau, Anna, Leal, Lucía, Wahi, Jessica E., Setien-Baranda, Fernando, Szczesna, Karolina, Moutinho, Catia, Martinez-Cardus, Anna, Heyn, Holger, Sandoval, Juan, Puertas, Sara, Vidal, August, Sanjuan, Xavier, Martinez-Balibrea, Eva, Viñals, Francesc, Perales, Jose C., Bramsem, Jesper B., Ørntoft, Torben F., Andersen, Claus L., Tabernero, Josep, McDermott, Ultan, Boxer, Matthew B., Vander Heiden, Matthew G., Albar, Juan Pablo, Esteller, Manel
Publicado 2016