A probabilistic model of biological ageing of the lungs for analysing the effects of smoking, asthma and COPD

por Chiappa, Silvia, Winn, John, Viñuela, Ana, Tipney, Hannah, Spector, Timothy David
Publicado 2013

Genome-Wide Gene Expression Analysis in Response to Organophosphorus Pesticide Chlorpyrifos and Diazinon in C. elegans

por Viñuela, Ana, Snoek, L. Basten, Riksen, Joost A. G., Kammenga, Jan E.
Publicado 2010

Gene Expression Modifications by Temperature-Toxicants Interactions in Caenorhabditis elegans

por Viñuela, Ana, Snoek, L. Basten, Riksen, Joost A. G., Kammenga, Jan E.
Publicado 2011

Aging Uncouples Heritability and Expression-QTL in Caenorhabditis elegans

por Viñuela, Ana, Snoek, L. Basten, Riksen, Joost A. G., Kammenga, Jan E.
Publicado 2012

Tensor decomposition for multi-tissue gene expression experiments

por Hore, Victoria, Viñuela, Ana, Buil, Alfonso, Knight, Julian, McCarthy, Mark I, Small, Kerrin, Marchini, Jonathan
Publicado 2016

Pathway-Based Factor Analysis of Gene Expression Data Produces Highly Heritable Phenotypes That Associate with Age

por Anand Brown, Andrew, Ding, Zhihao, Viñuela, Ana, Glass, Dan, Parts, Leopold, Spector, Tim, Winn, John, Durbin, Richard
Publicado 2015

Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort

por Viñuela, Ana, Brown, Andrew A, Buil, Alfonso, Tsai, Pei-Chien, Davies, Matthew N, Bell, Jordana T, Dermitzakis, Emmanouil T, Spector, Timothy D, Small, Kerrin S
Publicado 2018

Genetic interactions affecting human gene expression identified by variance association mapping

por Brown, Andrew Anand, Buil, Alfonso, Viñuela, Ana, Lappalainen, Tuuli, Zheng, Hou-Feng, Richards, J Brent, Small, Kerrin S, Spector, Timothy D, Dermitzakis, Emmanouil T, Durbin, Richard
Publicado 2014

Adiposity-Dependent Regulatory Effects on Multi-tissue Transcriptomes

por Glastonbury, Craig A., Viñuela, Ana, Buil, Alfonso, Halldorsson, Gisli H., Thorleifsson, Gudmar, Helgason, Hannes, Thorsteinsdottir, Unnur, Stefansson, Kari, Dermitzakis, Emmanouil T., Spector, Tim D., Small, Kerrin S.
Publicado 2016

Time-dependent genetic effects on gene expression implicate aging processes

por Bryois, Julien, Buil, Alfonso, Ferreira, Pedro G., Panousis, Nikolaos I., Brown, Andrew A., Viñuela, Ana, Planchon, Alexandra, Bielser, Deborah, Small, Kerrin, Spector, Tim, Dermitzakis, Emmanouil T.
Publicado 2017

Mapping eQTLs with RNA-seq reveals novel susceptibility genes, non-coding RNAs and alternative-splicing events in systemic lupus erythematosus

por Odhams, Christopher A., Cortini, Andrea, Chen, Lingyan, Roberts, Amy L., Viñuela, Ana, Buil, Alfonso, Small, Kerrin S., Dermitzakis, Emmanouil T., Morris, David L., Vyse, Timothy J., Cunninghame Graham, Deborah S.
Publicado 2017

Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance

por Shum, Michael, Segawa, Mayuko, Gharakhanian, Raffi, Viñuela, Ana, Wortham, Matthew, Baghdasarian, Siyouneh, Wolf, Dane M., Sereda, Samuel B., Nocito, Laura, Stiles, Linsey, Zhou, Zhiqiang, Gutierrez, Vincent, Sander, Maike, Shirihai, Orian S., Liesa, Marc
Publicado 2021

Integrated GWAS and Gene Expression Suggest ORM1 as a Potential Regulator of Plasma Levels of Cell-Free DNA and Thrombosis Risk

por Lopez, Sonia, Martinez-Perez, Angel, Rodriguez-Rius, Alba, Viñuela, Ana, Brown, Andrew A., Martin-Fernandez, Laura, Vilalta, Noelia, Arús, Marc, Panousis, Nikolaos I., Buil, Alfonso, Sabater-Lleal, Maria, Souto, Juan Carlos, Dermitzakis, Emmanouil T., Soria, Jose Manuel
Publicado 2022

Circulating Proteomic Signatures of Chronological Age

por Menni, Cristina, Kiddle, Steven J., Mangino, Massimo, Viñuela, Ana, Psatha, Maria, Steves, Claire, Sattlecker, Martina, Buil, Alfonso, Newhouse, Stephen, Nelson, Sally, Williams, Stephen, Voyle, Nicola, Soininen, Hilkka, Kloszewska, Iwona, Mecocci, Patrizia, Tsolaki, Magda, Vellas, Bruno, Lovestone, Simon, Spector, Tim D., Dobson, Richard, Valdes, Ana M.
Publicado 2015

Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health

por Tsai, Pei-Chien, Glastonbury, Craig A., Eliot, Melissa N., Bollepalli, Sailalitha, Yet, Idil, Castillo-Fernandez, Juan E., Carnero-Montoro, Elena, Hardiman, Thomas, Martin, Tiphaine C., Vickers, Alice, Mangino, Massimo, Ward, Kirsten, Pietiläinen, Kirsi H., Deloukas, Panos, Spector, Tim D., Viñuela, Ana, Loucks, Eric B., Ollikainen, Miina, Kelsey, Karl T., Small, Kerrin S., Bell, Jordana T.
Publicado 2018

Gene expression changes with age in skin, adipose tissue, blood and brain

por Glass, Daniel, Viñuela, Ana, Davies, Matthew N, Ramasamy, Adaikalavan, Parts, Leopold, Knowles, David, Brown, Andrew A, Hedman, Åsa K, Small, Kerrin S, Buil, Alfonso, Grundberg, Elin, Nica, Alexandra C, Di Meglio, Paola, Nestle, Frank O, Ryten, Mina, Durbin, Richard, McCarthy, Mark I, Deloukas, Panagiotis, Dermitzakis, Emmanouil T, Weale, Michael E, Bataille, Veronique, Spector, Tim D
Publicado 2013

An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins

por Yuan, Wei, Xia, Yudong, Bell, Christopher G., Yet, Idil, Ferreira, Teresa, Ward, Kirsten J., Gao, Fei, Loomis, A. Katrina, Hyde, Craig L., Wu, Honglong, Lu, Hanlin, Liu, Yuan, Small, Kerrin S., Viñuela, Ana, Morris, Andrew P., Berdasco, María, Esteller, Manel, Brosnan, M. Julia, Deloukas, Panos, McCarthy, Mark I., John, Sally L., Bell, Jordana T., Wang, Jun, Spector, Tim D.
Publicado 2014

Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases

por Carland, Corinne, Png, Grace, Malarstig, Anders, Kho, Pik Fang, Gustafsson, Stefan, Michaelsson, Karl, Lind, Lars, Tsafantakis, Emmanouil, Karaleftheri, Maria, Dedoussis, George, Ramisch, Anna, Macdonald-Dunlop, Erin, Klaric, Lucija, Joshi, Peter K., Chen, Yan, Björck, Hanna M., Eriksson, Per, Carrasco-Zanini, Julia, Wheeler, Eleanor, Suhre, Karsten, Gilly, Arthur, Zeggini, Eleftheria, Viñuela, Ana, Dermitzakis, Emmanouil T., Wilson, James F., Langenberg, Claudia, Thareja, Gaurav, Halama, Anna, Schmidt, Frank, Zanetti, Daniela, Assimes, Themistocles
Publicado 2023

Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition

por Small, Kerrin S., Todorčević, Marijana, Civelek, Mete, El-Sayed Moustafa, Julia S., Wang, Xiao, Simon, Michelle M., Fernandez-Tajes, Juan, Mahajan, Anubha, Horikoshi, Momoko, Hugill, Alison, Glastonbury, Craig A., Quaye, Lydia, Neville, Matt J., Sethi, Siddharth, Yon, Marianne, Pan, Calvin, Che, Nam, Viñuela, Ana, Tsai, Pei-Chien, Nag, Abhishek, Buil, Alfonso, Thorleifsson, Gudmar, Raghavan, Avanthi, Ding, Qiurong, Morris, Andrew P., Bell, Jordana T., Thorsteinsdottir, Unnur, Stefansson, Kari, Laakso, Markku, Dahlman, Ingrid, Arner, Peter, Gloyn, Anna L., Musunuru, Kiran, Lusis, Aldons J., Cox, Roger, Karpe, Fredrik, McCarthy, Mark I.
Publicado 2018

The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study

por Koivula, Robert W., Atabaki-Pasdar, Naeimeh, Giordano, Giuseppe N., White, Tom, Adamski, Jerzy, Bell, Jimmy D., Beulens, Joline, Brage, Søren, Brunak, Søren, De Masi, Federico, Dermitzakis, Emmanouil T., Forgie, Ian M., Frost, Gary, Hansen, Torben, Hansen, Tue H., Hattersley, Andrew, Kokkola, Tarja, Kurbasic, Azra, Laakso, Markku, Mari, Andrea, McDonald, Timothy J., Pedersen, Oluf, Rutters, Femke, Schwenk, Jochen M., Teare, Harriet J. A., Thomas, E. Louise, Vinuela, Ana, Mahajan, Anubha, McCarthy, Mark I., Ruetten, Hartmut, Walker, Mark, Pearson, Ewan, Pavo, Imre, Franks, Paul W.
Publicado 2020