Loss and Gain of Function in SERPINB11: An Example of a Gene under Selection on Standing Variation, with Implications for Host-Pathogen Interactions

por Seixas, Susana, Ivanova, Nevyana, Ferreira, Zelia, Rocha, Jorge, Victor, Bruno L.
Publicado 2012

Major Achievements in the Design of Quadruplex-Interactive Small Molecules

por Mendes, Eduarda, Aljnadi, Israa M., Bahls, Bárbara, Victor, Bruno L., Paulo, Alexandra
Publicado 2022

Unraveling the Aquaporin-3 Inhibitory Effect of Rottlerin by Experimental and Computational Approaches

por Paccetti-Alves, Inês, Batista, Marta S. P., Pimpão, Catarina, Victor, Bruno L., Soveral, Graça
Publicado 2023

Rescue of Rare CFTR Trafficking Mutants Highlights a Structural Location-Dependent Pattern for Correction

por Zacarias, Sónia, Batista, Marta S. P., Ramalho, Sofia S., Victor, Bruno L., Farinha, Carlos M.
Publicado 2023

Optimization of an in Silico Protocol Using Probe Permeabilities to Identify Membrane Pan-Assay Interference Compounds

por Magalhães, Pedro R., Reis, Pedro B. P. S., Vila-Viçosa, Diogo, Machuqueiro, Miguel, Victor, Bruno L.
Publicado 2022

Fusing simulation and experiment: The effect of mutations on the structure and activity of the influenza fusion peptide

por Lousa, Diana, Pinto, Antónia R. T., Victor, Bruno L., Laio, Alessandro, Veiga, Ana S., Castanho, Miguel A. R. B., Soares, Cláudio M.
Publicado 2016

New (Iso)quinolinyl-pyridine-2,6-dicarboxamide G-Quadruplex Stabilizers. A Structure-Activity Relationship Study

por Cadoni, Enrico, Magalhães, Pedro R., Emídio, Rita M., Mendes, Eduarda, Vítor, Jorge, Carvalho, Josué, Cruz, Carla, Victor, Bruno L., Paulo, Alexandra
Publicado 2021

In Silico Characterization of African Swine Fever Virus Nucleoprotein p10 Interaction with DNA

por Istrate, Claudia, Marques, Jéssica, Bule, Pedro, Correia, Sílvia, Aires-da-Silva, Frederico, Duarte, Marlene, Reis, Ana Luísa, Machuqueiro, Miguel, Leitão, Alexandre, Victor, Bruno L.
Publicado 2022

Probing the Interactions of Thiazole Abietane Inhibitors with the Human Serine Hydrolases ABHD16A and ABHD12

por Ahonen, Tiina J., Ng, Choa P., Farinha, Beatriz, Almeida, Bárbara, Victor, Bruno L., Reynolds, Christopher, Kalso, Eija, Yli-Kauhaluoma, Jari, Greaves, Jennifer, Moreira, Vânia M.
Publicado 2023

Alchemical Design of Pharmacological Chaperones with Higher Affinity for Phenylalanine Hydroxylase

por Conde-Giménez, María, Galano-Frutos, Juan José, Galiana-Cameo, María, Mahía, Alejandro, Victor, Bruno L., Salillas, Sandra, Velázquez-Campoy, Adrián, Brito, Rui M. M., Gálvez, José Antonio, Díaz-de-Villegas, María D., Sancho, Javier
Publicado 2022