P-Glycoprotein–Mediated Efflux Reduces the In Vivo Efficacy of a Therapeutic Targeting the Gastrointestinal Parasite Cryptosporidium

por Arnold, Samuel L M, Choi, Ryan, Hulverson, Matthew A, Whitman, Grant R, Mccloskey, Molly C, Dorr, Carlie S, Vidadala, Rama S R, Khatod, Mansi, Morada, Mary, Barrett, Lynn K, Maly, Dustin J, Yarlett, Nigel, Van Voorhis, Wesley C
Publicado 2019

Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection

por Arnold, Samuel L. M., Choi, Ryan, Hulverson, Matthew A., Schaefer, Deborah A., Vinayak, Sumiti, Vidadala, Rama S. R., McCloskey, Molly C., Whitman, Grant R., Huang, Wenlin, Barrett, Lynn K., Ojo, Kayode K., Fan, Erkang, Maly, Dustin J., Riggs, Michael W., Striepen, Boris, Van Voorhis, Wesley C.
Publicado 2017

Bumped kinase inhibitor 1369 is effective against Cystoisospora suis in vivo and in vitro

por Shrestha, Aruna, Ojo, Kayode K., Koston, Florian, Ruttkowski, Bärbel, Vidadala, Rama S.R., Dorr, Carlie S., Navaluna, Edelmar D., Whitman, Grant R., Barrett, Kayleigh F., Barrett, Lynn K., Hulverson, Matthew A., Choi, Ryan, Michaels, Samantha A., Maly, Dustin J., Hemphill, Andrew, Van Voorhis, Wesley C., Joachim, Anja
Publicado 2019