Mutational Studies of the Mersacidin Leader Reveal the Function of Its Unique Two-Step Leader Processing Mechanism

por Viel, Jakob H., Kuipers, Oscar P.
Publicado 2022

Modular Use of the Uniquely Small Ring A of Mersacidin Generates the Smallest Ribosomally Produced Lanthipeptide

por Viel, Jakob H., Kuipers, Oscar P.
Publicado 2022

Heterologous Expression of Mersacidin in Escherichia coli Elucidates the Mode of Leader Processing

por Viel, Jakob H., Jaarsma, Ate H., Kuipers, Oscar P.
Publicado 2021

Synthesis and Characterization of Heterodimers and Fluorescent Nisin Species by Incorporation of Methionine Analogues and Subsequent Click Chemistry

por Deng, Jingjing, Viel, Jakob H., Chen, Jingqi, Kuipers, Oscar P.
Publicado 2020

Semisynthetic Macrocyclic Lipo-lanthipeptides Display Antimicrobial Activity Against Bacterial Pathogens

por Zhao, Xinghong, Xu, Yanli, Viel, Jakob H., Kuipers, Oscar P.
Publicado 2021

Characterization of Leader Processing Shows That Partially Processed Mersacidin Is Activated by AprE After Export

por Viel, Jakob H., van Tilburg, Amanda Y., Kuipers, Oscar P.
Publicado 2021

Conjugation of Synthetic Polyproline Moietes to Lipid II Binding Fragments of Nisin Yields Active and Stable Antimicrobials

por Deng, Jingjing, Viel, Jakob H., Kubyshkin, Vladimir, Budisa, Nediljko, Kuipers, Oscar P.
Publicado 2020

Rapid and Selective Chemical Editing of Ribosomally Synthesized and Post‐Translationally Modified Peptides (RiPPs) via Cu(II)‐Catalyzed β‐Borylation of Dehydroamino Acids

por de Vries, Reinder H., Viel, Jakob H., Kuipers, Oscar P., Roelfes, Gerard
Publicado 2020

Selective Modification of Ribosomally Synthesized and Post‐Translationally Modified Peptides (RiPPs) through Diels–Alder Cycloadditions on Dehydroalanine Residues

por de Vries, Reinder H., Viel, Jakob H., Oudshoorn, Ruben, Kuipers, Oscar P., Roelfes, Gerard
Publicado 2019

BAGEL4: a user-friendly web server to thoroughly mine RiPPs and bacteriocins

por van Heel, Auke J, de Jong, Anne, Song, Chunxu, Viel, Jakob H, Kok, Jan, Kuipers, Oscar P
Publicado 2018