Ion Channel Partnerships: Odd and Not-So-Odd Couples Controlling Neuronal Ion Channel Function

por Vierra, Nicholas C., Trimmer, James S.
Publicado 2022

Osteopontin activates the diabetes-associated potassium channel TALK-1 in pancreatic β-cells

por Dickerson, Matthew T., Vierra, Nicholas C., Milian, Sarah C., Dadi, Prasanna K., Jacobson, David A.
Publicado 2017

Kv2.1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons

por Vierra, Nicholas C, Kirmiz, Michael, van der List, Deborah, Santana, L Fernando, Trimmer, James S
Publicado 2019

Regulation of neuronal excitation–transcription coupling by Kv2.1-induced clustering of somatic L-type Ca(2+) channels at ER-PM junctions

por Vierra, Nicholas C., O’Dwyer, Samantha C., Matsumoto, Collin, Santana, L. Fernando, Trimmer, James S.
Publicado 2021

Type 2 Diabetes–Associated K(+) Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose Homeostasis

por Vierra, Nicholas C., Dadi, Prasanna K., Jeong, Imju, Dickerson, Matthew, Powell, David R., Jacobson, David A.
Publicado 2015

NPC1-dependent alterations in K(V)2.1–Ca(V)1.2 nanodomains drive neuronal death in models of Niemann-Pick Type C disease

por Casas, Maria, Murray, Karl D., Hino, Keiko, Vierra, Nicholas C., Simó, Sergi, Trimmer, James S., Dixon, Rose E., Dickson, Eamonn J.
Publicado 2023

TALK-1 reduces delta-cell endoplasmic reticulum and cytoplasmic calcium levels limiting somatostatin secretion

por Vierra, Nicholas C., Dickerson, Matthew T., Jordan, Kelli L., Dadi, Prasanna K., Kadare, Ketaki A., Altman, Molly K., Milian, Sarah C., Jacobson, David A.
Publicado 2018

Epilepsy and neurobehavioral abnormalities in mice with a dominant-negative KCNB1 pathogenic variant

por Hawkins, Nicole A., Misra, Sunita N, Jurado, Manuel, Kang, Seok Kyu, Vierra, Nicholas C., Nguyen, Kimberly, Wren, Lisa, George, Alfred L., Trimmer, James S., Kearney, Jennifer A.
Publicado 2020

The formation of K(V)2.1 macro-clusters is required for sex-specific differences in L-type Ca(V)1.2 clustering and function in arterial myocytes

por Matsumoto, Collin, O’Dwyer, Samantha C., Manning, Declan, Hernandez-Hernandez, Gonzalo, Rhana, Paula, Fong, Zhihui, Sato, Daisuke, Clancy, Colleen E., Vierra, Nicholas C., Trimmer, James S., Santana, L. Fernando
Publicado 2023

The formation of K(V)2.1 macro-clusters is required for sex-specific differences in L-type Ca(V)1.2 clustering and function in arterial myocytes

por Matsumoto, Collin, O’Dwyer, Samantha C., Manning, Declan, Hernandez-Hernandez, Gonzalo, Rhana, Paula, Fong, Zhihui, Sato, Daisuke, Clancy, Colleen E., Vierra, Nicholas C., Trimmer, James S., Fernando Santana, L.
Publicado 2023

Neuronal ER-plasma membrane junctions couple excitation to Ca(2+)-activated PKA signaling

por Vierra, Nicholas C., Ribeiro-Silva, Luisa, Kirmiz, Michael, van der List, Deborah, Bhandari, Pradeep, Mack, Olivia A., Carroll, James, Le Monnier, Elodie, Aicher, Sue A., Shigemoto, Ryuichi, Trimmer, James S.
Publicado 2023

β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions

por Zhu, Lu, Almaça, Joana, Dadi, Prasanna K., Hong, Hao, Sakamoto, Wataru, Rossi, Mario, Lee, Regina J., Vierra, Nicholas C., Lu, Huiyan, Cui, Yinghong, McMillin, Sara M., Perry, Nicole A., Gurevich, Vsevolod V., Lee, Amy, Kuo, Bryan, Leapman, Richard D., Matschinsky, Franz M., Doliba, Nicolai M., Urs, Nikhil M., Caron, Marc G., Jacobson, David A., Caicedo, Alejandro, Wess, Jürgen
Publicado 2017