Conformational Analysis of the DFG-Out Kinase Motif and Biochemical Profiling of Structurally Validated Type II Inhibitors

por Vijayan, R. S. K., He, Peng, Modi, Vivek, Duong-Ly, Krisna C., Ma, Haiching, Peterson, Jeffrey R., Dunbrack, Roland L., Levy, Ronald M.
Publicado 2014

Distinguishing Binders from False Positives by Free Energy Calculations: Fragment Screening Against the Flap Site of HIV Protease

por Deng, Nanjie, Forli, Stefano, He, Peng, Perryman, Alex, Wickstrom, Lauren, Vijayan, R. S. K., Tiefenbrunn, Theresa, Stout, David, Gallicchio, Emilio, Olson, Arthur J., Levy, Ronald M.
Publicado 2014

Structure-based virtual screening workflow to identify antivirals targeting HIV-1 capsid

por Sun, Qinfang, Biswas, Avik, Vijayan, R. S. K., Craveur, Pierrick, Forli, Stefano, Olson, Arthur J., Castaner, Andres Emanuelli, Kirby, Karen A., Sarafianos, Stefan G., Deng, Nanjie, Levy, Ronald
Publicado 2022

Structure-based classification predicts drug response in EGFR-mutant NSCLC

por Robichaux, Jacqulyne P., Le, Xiuning, Vijayan, R. S. K., Hicks, J. Kevin, Heeke, Simon, Elamin, Yasir Y., Lin, Heather Y., Udagawa, Hibiki, Skoulidis, Ferdinandos, Tran, Hai, Varghese, Susan, He, Junqin, Zhang, Fahao, Nilsson, Monique B., Hu, Lemei, Poteete, Alissa, Rinsurongkawong, Waree, Zhang, Xiaoshan, Ren, Chenghui, Liu, Xiaoke, Hong, Lingzhi, Zhang, Jianjun, Diao, Lixia, Madison, Russell, Schrock, Alexa B., Saam, Jennifer, Raymond, Victoria, Fang, Bingliang, Wang, Jing, Ha, Min Jin, Cross, Jason B., Gray, Jhanelle E., Heymach, John V.
Publicado 2021