Neurotrophin receptors, gamma-secretase inhibitors, and neurodegeneration of basal forebrain cholinergic neurons

por Vilar, Marçal
Publicado 2021

Regulation of Neurogenesis by Neurotrophins during Adulthood: Expected and Unexpected Roles

por Vilar, Marçal, Mira, Helena
Publicado 2016

Brain Expressed and X-Linked (Bex) Proteins Are Intrinsically Disordered Proteins (IDPs) and Form New Signaling Hubs

por Fernandez, Eva M., Díaz-Ceso, María D., Vilar, Marçal
Publicado 2015

Identification of a guanine-specific pocket in the protein N of SARS-CoV-2

por Rafael Ciges-Tomas, J., Franco, María Luisa, Vilar, Marçal
Publicado 2022

Tiam1 as a Signaling Mediator of Nerve Growth Factor-Dependent Neurite Outgrowth

por Shirazi Fard, Shahrzad, Kele, Julianna, Vilar, Marçal, Paratcha, Gustavo, Ledda, Fernanda
Publicado 2010

P45 Forms a Complex with FADD and Promotes Neuronal Cell Survival Following Spinal Cord Injury

por Sung, Tsung-Chang, Chen, Zhijiang, Thuret, Sandrine, Vilar, Marçal, Gage, Fred H., Riek, Roland, Lee, Kuo-Fen
Publicado 2013

TrkA-mediated endocytosis of p75-CTF prevents cholinergic neuron death upon γ-secretase inhibition

por Franco, María Luisa, García-Carpio, Irmina, Comaposada-Baró, Raquel, Escribano-Saiz, Juan J, Chávez-Gutiérrez, Lucía, Vilar, Marçal
Publicado 2021

Heterodimerization of p45–p75 Modulates p75 Signaling: Structural Basis and Mechanism of Action

por Vilar, Marçal, Sung, Tsung-Chang, Chen, Zhijiang, García-Carpio, Irmina, Fernandez, Eva M., Xu, Jiqing, Riek, Roland, Lee, Kuo-Fen
Publicado 2014

Intrinsically disordered regions couple the ligand binding and kinase activation of Trk neurotrophin receptors

por Kot, Erik F., Franco, María L., Vasilieva, Ekaterina V., Shabalkina, Alexandra V., Arseniev, Alexander S., Goncharuk, Sergey A., Mineev, Konstantin S., Vilar, Marçal
Publicado 2022

Forkhead transcription factor FKH-8 cooperates with RFX in the direct regulation of sensory cilia in Caenorhabditis elegans

por Brocal-Ruiz, Rebeca, Esteve-Serrano, Ainara, Mora-Martínez, Carlos, Franco-Rivadeneira, Maria Luisa, Swoboda, Peter, Tena, Juan J, Vilar, Marçal, Flames, Nuria
Publicado 2023

Cholinergic neurodegeneration and cholesterol metabolism dysregulation by constitutive p75(NTR) signaling in the p75(exonIII)-KO mice

por Comaposada-Baró, Raquel, Benito-Martínez, Andrea, Escribano-Saiz, Juan Julian, Franco, María Luisa, Ceccarelli, Lorenzo, Calatayud-Baselga, Isabel, Mira, Helena, Vilar, Marçal
Publicado 2023

Ionic self-complementarity induces amyloid-like fibril formation in an isolated domain of a plant copper metallochaperone protein

por Mira, Helena, Vilar, Marçal, Esteve, Vicent, Martinell, Marc, Kogan, Marcelo J, Giralt, Ernest, Salom, David, Mingarro, Ismael, Peñarrubia, Lola, Pérez-Payá, Enrique
Publicado 2004

Senescent accelerated prone 8 (SAMP8) mice as a model of age dependent neuroinflammation

por Fernández, Andrés, Quintana, Elena, Velasco, Patricia, Moreno-Jimenez, Belén, de Andrés, Belén, Gaspar, Maria Luisa, Liste, Isabel, Vilar, Marçal, Mira, Helena, Cano, Eva
Publicado 2021

Interaction between the transmembrane domains of neurotrophin receptors p75 and TrkA mediates their reciprocal activation

por Franco, María L., Nadezhdin, Kirill D., Light, Taylor P., Goncharuk, Sergey A., Soler-Lopez, Andrea, Ahmed, Fozia, Mineev, Konstantin S., Hristova, Kalina, Arseniev, Alexander S., Vilar, Marçal
Publicado 2021

Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses

por Cortegano, Isabel, Rodríguez, Mercedes, Martín, Isabel, Prado, Maria Carmen, Ruíz, Carolina, Hortigüela, Rafael, Alía, Mario, Vilar, Marçal, Mira, Helena, Cano, Eva, Domínguez, Mercedes, de Andrés, Belén, Gaspar, María Luisa
Publicado 2017

Functional and structural deficiencies of Gemin5 variants associated with neurological disorders

por Francisco-Velilla, Rosario, Embarc-Buh, Azman, del Caño-Ochoa, Francisco, Abellan, Salvador, Vilar, Marçal, Alvarez, Sara, Fernandez-Jaen, Alberto, Kour, Sukhleen, Rajan, Deepa S, Pandey, Udai Bhan, Ramón-Maiques, Santiago, Martinez-Salas, Encarnacion
Publicado 2022

Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling

por Zoltowska, Katarzyna Marta, Das, Utpal, Lismont, Sam, Enzlein, Thomas, Maesako, Masato, Houser, Mei CQ, Franco, María Luisa, Moreira, Diana Gomes, Karachentsev, Dmitry, Becker, Ann, Hopf, Carsten, Vilar, Marçal, Berezovska, Oksana, Mobley, William, Chávez-Gutiérrez, Lucía
Publicado 2023

The transcription factor LEF1 interacts with NFIX and switches isoforms during adult hippocampal neural stem cell quiescence

por García-Corzo, Laura, Calatayud-Baselga, Isabel, Casares-Crespo, Lucía, Mora-Martínez, Carlos, Julián Escribano-Saiz, Juan, Hortigüela, Rafael, Asenjo-Martínez, Andrea, Jordán-Pla, Antonio, Ercoli, Stefano, Flames, Nuria, López-Alonso, Victoria, Vilar, Marçal, Mira, Helena
Publicado 2022

Psychedelics promote plasticity by directly binding to BDNF receptor TrkB

por Moliner, Rafael, Girych, Mykhailo, Brunello, Cecilia A., Kovaleva, Vera, Biojone, Caroline, Enkavi, Giray, Antenucci, Lina, Kot, Erik F., Goncharuk, Sergey A., Kaurinkoski, Katja, Kuutti, Mirjami, Fred, Senem M., Elsilä, Lauri V., Sakson, Sven, Cannarozzo, Cecilia, Diniz, Cassiano R. A. F., Seiffert, Nina, Rubiolo, Anna, Haapaniemi, Hele, Meshi, Elsa, Nagaeva, Elina, Öhman, Tiina, Róg, Tomasz, Kankuri, Esko, Vilar, Marçal, Varjosalo, Markku, Korpi, Esa R., Permi, Perttu, Mineev, Konstantin S., Saarma, Mart, Vattulainen, Ilpo, Casarotto, Plinio C., Castrén, Eero
Publicado 2023