Shining light on location-biased cAMP signaling

por Vilardaga, Jean-Pierre, Sutkeviciute, Ieva, Peña, Karina A.
Publicado 2021

SAT-040 Structural Mechanisms of Parathyroid Hormone (PTH) Binding to Receptor and Regulation of Endosomal Signaling

por Clark, Lisa, Bondarenko, Vasyl, Tang, Pei, Vilardaga, Jean-Pierre
Publicado 2019

MON-538 Ca(2+)Allostery in PTH-Receptor Signaling

por White, Alex, Sutkeviciute, Ieva, Jean-Alphonse, Frederic, Xiao, Kunhong, Vilardaga, Jean-Pierre
Publicado 2019

OR30-3 Structural Basis of Activation and Sustained Signaling by the PTH Receptor

por Sutkeviciute, Ieva, Zhao, Li-Hua, Zhang, Yan, Xu, H Eric, Vilardaga, Jean-Pierre
Publicado 2019

OR21-3 Spatial Signaling Bias of a Gain-of-Function PTH1R Mutant Associated with Delayed Ossification in Eiken Syndrome

por Dean, Thomas, Gardella, Thomas, Jüppner, Harald, Savransky, Sophia, Vilardaga, Jean-Pierre, Portales-Castillo, Ignacio
Publicado 2022

Retromer terminates the generation of cAMP by internalized PTH-receptors

por Feinstein, Timothy N., Wehbi, Vanessa L., Ardura, Juan, Wheeler, David S., Ferrandon, Sebastien, Gardella, Thomas J., Vilardaga, Jean-Pierre
Publicado 2011

OR23-01 The Nonredundant Role Of Beta-Amyloid In Mediating Tonic PTH Secretion In Physiological And Pathological States

por Tu, Chia-Ling, Cheng, Zhiqiang, Alejandra Pena, Karina, Szeto, Nicholas, Ann Sosa, Julie, Vilardaga, Jean-Pierre, Koh, James, Chang, Wenhan
Publicado 2023

Altered Signaling and Desensitization Responses in PTH1R Mutants Associated with Eiken Syndrome

por Portales-Castillo, Ignacio, Dean, Thomas, Cheloha, Ross W., Creemer, Brendan A., Vilardaga, Jean-Pierre, Savransky, Sofya, Khatri, Ashok, Jüppner, Harald, Gardella, Thomas J.
Publicado 2023

Cdc42 activation couples fluid shear stress to apical endocytosis in proximal tubule cells

por Bhattacharyya, Sohinee, Jean‐Alphonse, Frédéric G., Raghavan, Venkatesan, McGarvey, Jennifer C., Rbaibi, Youssef, Vilardaga, Jean‐Pierre, Carattino, Marcelo D., Weisz, Ora A.
Publicado 2017

Biased GPCR signaling by the native parathyroid hormone–related protein 1 to 141 relative to its N-terminal fragment 1 to 36

por Peña, Karina A., White, Alex D., Savransky, Sofya, Castillo, Ignacio Portales, Jean-Alphonse, Frédéric G., Gardella, Thomas J., Sutkeviciute, Ieva, Vilardaga, Jean-Pierre
Publicado 2022

Uncovering Caffeine’s Adenosine A(2A) Receptor Inverse Agonism in Experimental Parkinsonism

por Fernández-Dueñas, Víctor, Gómez-Soler, Maricel, López-Cano, Marc, Taura, Jaume J., Ledent, Catherine, Watanabe, Masahiko, Jacobson, Kenneth A., Vilardaga, Jean-Pierre, Ciruela, Francisco
Publicado 2014

Endosomal GPCR signaling turned off by negative feedback actions of PKA and v-ATPase

por Gidon, Alexandre, Al-Bataineh, Mohammad M., Jean-Alphonse, Frederic G., Stevenson, Hilary, Watanabe, Tomoyuki, Louet, Claire, Khatri, Ashok, Calero, Guillermo, Pastor-Soler, Núria M., Gardella, Thomas J., Vilardaga, Jean-Pierre
Publicado 2014

Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation

por Clark, Lisa J., Krieger, James, White, Alex D., Bondarenko, Vasyl, Lei, Saifei, Fang, Fei, Lee, Ji Young, Doruker, Pemra, Böttke, Thore, Jean-Alphonse, Frederic, Tang, Pei, Gardella, Thomas J., Xiao, Kunhong, Sutkeviciute, Ieva, Coin, Irene, Bahar, Ivet, Vilardaga, Jean-Pierre
Publicado 2020

Precise druggability of the PTH type 1 receptor

por Sutkeviciute, Ieva, Lee, Ji Young, White, Alex D., Maria, Christian Santa, Peña, Karina A., Savransky, Sofya, Doruker, Pemra, Li, Hongchun, Lei, Saifei, Kaynak, Burak, Tu, Chialing, Clark, Lisa J., Sanker, Subramaniam, Gardella, Thomas J., Chang, Wenhan, Bahar, Ivet, Vilardaga, Jean-Pierre
Publicado 2022

PTH Hypersecretion Triggered by a GABA(B1) and Ca(2+)-sensing Receptor Heterocomplex in Hyperparathyroidism

por Chang, Wenhan, Tu, Chia-Ling, Jean-Alphonse, Frederic, Herberger, Amanda, Cheng, Zhiqiang, Hwong, Jenna, Ho, Hanson, Li, Alfred, Wang, Dawei, Liu, Hongda, White, Alex D., Suh, Insoo, Shen, Wen, Duh, Quan-Yang, Khanafshar, Elham, Shoback, Dolores M., Xiao, Kunhong, Vilardaga, Jean-Pierre
Publicado 2020

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein‐coupled receptors

por Alexander, Stephen PH, Christopoulos, Arthur, Davenport, Anthony P, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A, Abbracchio, Maria P, Alexander, Wayne, Al-hosaini, Khaled, Bäck, Magnus, Beaulieu, Jean‐Martin, Bernstein, Kenneth E., Bettler, Bernhard, Birdsall, Nigel JM, Blaho, Victoria, Bousquet, Corinne, Bräuner-Osborne, Hans, Burnstock, Geoffrey, Caló, Girolamo, Castaño, Justo P, Catt, Kevin J, Ceruti, Stefania, Chazot, Paul, Chiang, Nan, Chun, Jerold, Cianciulli, Antonia, Clapp, Lucie H, Couture, Réjean, Csaba, Zsolt, Dent, Gordon, Singh, Khuraijam Dhanachandra, Douglas, Steven D, Dournaud, Pascal, Eguchi, Satoru, Escher, Emanuel, Filardo, Edward, Fong, Tung M, Fumagalli, Marta, Gainetdinov, Raul R, de Gasparo, Marc, Gershengorn, Marvin, Gobeil, Fernand, Goodfriend, Theodore L, Goudet, Cyril, Gregory, Karen J, Gundlach, Andrew L, Hamann, Jörg, Hanson, Julien, Hauger, Richard L, Hay, Debbie, Heinemann, Akos, Hollenberg, Morley D, Holliday, Nicholas D, Horiuchi, Mastgugu, Hoyer, Daniel, Hunyady, László, Husain, Ahsan, Ijzerman, Adriaan P, Inagami, Tadashi, Jacobson, Kenneth A, Jensen, Robert T, Jockers, Ralf, Jonnalagadda, Deepa, Karnik, Sadashiva, Kaupmann, Klemens, Kemp, Jacqueline, Kennedy, Charles, Kihara, Yasuyuki, Kozielewicz, Paweł, Kreienkamp, Hans‐Jürgen, Kukkonen, Jyrki P, Langenhan, Tobias, Leach, Katie, Lecca, Davide, Lee, John D, Leeman, Susan E, Leprince, Jérôme, Lolait, Stephen J, Lupp, Amelie, Macrae, Robyn, Maguire, Janet, Mazella, Jean, McArdle, Craig A, Melmed, Shlomo, Michel, Martin C, Miller, Laurence, Mitolo, Vincenzo, Mouillac, Bernard, Murphy, Philip M, Nahon, Jean‐Louis, Norel, Xavier, Nyimanu, Duuamene, O'Carroll, Anne‐Marie, Offermanns, Stefan, Panaro, Maria A, Pertwee, Roger G, Pin, Jean‐Philippe, Prossnitz, Eric, Ramachandran, Rithwik, Reinscheid, Rainer K, Rondard, Philippe, Rovati, G Enrico, Ruzza, Chiara, Sanger, Gareth, Schöneberg, Torsten, Schulte, Gunnar, Schulz, Stefan, Segaloff, Deborah L, Serhan, Charles N, Stoddart, Leigh A, Sugimoto, Yukihiko, Summers, Roger, Tan, Valerie, Thomas, Walter, Timmermans, Pieter BMWM, Tirupula, Kalyan, Tulipano, Giovanni, Unal, Hamiyet, Unger, Thomas, Vanderheyden, Patrick, Vaudry, David, Vaudry, Hubert, Vilardaga, Jean‐Pierre, Walker, Christopher S, Ward, Donald T, Wester, Hans‐Jürgen, Willars, Gary B, Williams, Tom Lloyd, Woodruff, Trent M, Yao, Chengcan
Publicado 2019