Mycobacterium tuberculosis is extraordinarily sensitive to killing by a vitamin C-induced Fenton reaction

por Vilchèze, Catherine, Hartman, Travis, Weinrick, Brian, Jacobs, William R.
Publicado 2013

Sterilization by Adaptive Immunity of a Conditionally Persistent Mutant of Mycobacterium tuberculosis

por Vilchèze, Catherine, Porcelli, Steven A., Chan, John, Jacobs, William R.
Publicado 2021

An Anaerobic-Type α-Ketoglutarate Ferredoxin Oxidoreductase Completes the Oxidative Tricarboxylic Acid Cycle of Mycobacterium tuberculosis

por Baughn, Anthony D., Garforth, Scott J., Vilchèze, Catherine, Jacobs, William R.
Publicado 2009

Commonalities of Mycobacterium tuberculosis Transcriptomes in Response to Defined Persisting Macrophage Stresses

por Vilchèze, Catherine, Yan, Bo, Casey, Rosalyn, Hingley-Wilson, Suzie, Ettwiller, Laurence, Jacobs, William R.
Publicado 2022

Succinate Dehydrogenase is the Regulator of Respiration in Mycobacterium tuberculosis

por Hartman, Travis, Weinrick, Brian, Vilchèze, Catherine, Berney, Michael, Tufariello, Joanne, Cook, Gregory M., Jacobs, William R.
Publicado 2014

Acetic Acid, the Active Component of Vinegar, Is an Effective Tuberculocidal Disinfectant

por Cortesia, Claudia, Vilchèze, Catherine, Bernut, Audrey, Contreras, Whendy, Gómez, Keyla, de Waard, Jacobus, Jacobs, William R., Kremer, Laurent, Takiff, Howard
Publicado 2014

Rational Design of Biosafety Level 2-Approved, Multidrug-Resistant Strains of Mycobacterium tuberculosis through Nutrient Auxotrophy

por Vilchèze, Catherine, Copeland, Jacqueline, Keiser, Tracy L., Weisbrod, Torin, Washington, Jacqueline, Jain, Paras, Malek, Adel, Weinrick, Brian, Jacobs, William R.
Publicado 2018

Keto-Mycolic Acid-Dependent Pellicle Formation Confers Tolerance to Drug-Sensitive Mycobacterium tuberculosis

por Sambandan, Dhinakaran, Dao, Dee N., Weinrick, Brian C., Vilchèze, Catherine, Gurcha, Sudagar S., Ojha, Anil, Kremer, Laurent, Besra, Gurdyal S., Hatfull, Graham F., Jacobs, William R.
Publicado 2013

Mycobacterium bovis Strain Ravenel Is Attenuated in Cattle

por Hadi, Syeda A., Brenner, Evan P., Palmer, Mitchell V., Waters, W. Ray, Thacker, Tyler C., Vilchèze, Catherine, Larsen, Michelle H., Jacobs, William R., Sreevatsan, Srinand
Publicado 2022

Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis

por Vilchèze, Catherine, Av-Gay, Yossef, Attarian, Rodgoun, Liu, Zhen, Hazbón, Manzour H, Colangeli, Roberto, Chen, Bing, Liu, Weijun, Alland, David, Sacchettini, James C, Jacobs, William R
Publicado 2008

Enhanced Specialized Transduction Using Recombineering in Mycobacterium tuberculosis

por Tufariello, JoAnn M., Malek, Adel A., Vilchèze, Catherine, Cole, Laura E., Ratner, Hannah K., González, Pablo A., Jain, Paras, Hatfull, Graham F., Larsen, Michelle H., Jacobs, William R.
Publicado 2014

Dual-Reporter Mycobacteriophages (Φ(2)DRMs) Reveal Preexisting Mycobacterium tuberculosis Persistent Cells in Human Sputum

por Jain, Paras, Weinrick, Brian C., Kalivoda, Eric J., Yang, Hui, Munsamy, Vanisha, Vilcheze, Catherine, Weisbrod, Torin R., Larsen, Michelle H., O’Donnell, Max R., Pym, Alexander, Jacobs, William R.
Publicado 2016

Transcriptional Regulation of Multi-Drug Tolerance and Antibiotic-Induced Responses by the Histone-Like Protein Lsr2 in M. tuberculosis

por Colangeli, Roberto, Helb, Danica, Vilchèze, Catherine, Hazbón, Manzour Hernando, Lee, Chee-Gun, Safi, Hassan, Sayers, Brendan, Sardone, Irene, Jones, Marcus B, Fleischmann, Robert D, Peterson, Scott N, Jacobs, William R, Alland, David
Publicado 2007

Targeting Mycobacterium tuberculosis Tumor Necrosis Factor Alpha-Downregulating Genes for the Development of Antituberculous Vaccines

por Olsen, Aaron, Chen, Yong, Ji, Qingzhou, Zhu, Guofeng, De Silva, Aruna Dharshan, Vilchèze, Catherine, Weisbrod, Torin, Li, Weimin, Xu, Jiayong, Larsen, Michelle, Zhang, Jinghang, Porcelli, Steven A., Jacobs, William R., Chan, John
Publicado 2016

Antituberculosis thiophenes define a requirement for Pks13 in mycolic acid biosynthesis

por Wilson, Regina, Kumar, Pradeep, Parashar, Vijay, Vilchèze, Catherine, Veyron-Churlet, Romain, Freundlich, Joel S., Barnes, S. Whitney, Walker, John R., Szymonifka, Michael J., Marchiano, Emily, Shenai, Shubhada, Colangeli, Roberto, Jacobs, William R., Neiditch, Matthew B., Kremer, Laurent, Alland, David
Publicado 2013

Phosphorylation of KasB Regulates Virulence and Acid-Fastness in Mycobacterium tuberculosis

por Vilchèze, Catherine, Molle, Virginie, Carrère-Kremer, Séverine, Leiba, Jade, Mourey, Lionel, Shenai, Shubhada, Baronian, Grégory, Tufariello, Joann, Hartman, Travis, Veyron-Churlet, Romain, Trivelli, Xavier, Tiwari, Sangeeta, Weinrick, Brian, Alland, David, Guérardel, Yann, Jacobs, William R., Kremer, Laurent
Publicado 2014

The Complete Genome Sequence of the Emerging Pathogen Mycobacterium haemophilum Explains Its Unique Culture Requirements

por Tufariello, JoAnn M., Kerantzas, Christopher A., Vilchèze, Catherine, Calder, R. Brent, Nordberg, Eric K., Fischer, Jack A., Hartman, Travis E., Yang, Eva, Driscoll, Timothy, Cole, Laura E., Sebra, Robert, Maqbool, Shahina B., Wattam, Alice R., Jacobs, William R.
Publicado 2015

Elimination of PknL and MSMEG_4242 in Mycobacterium smegmatis alters the character of the outer cell envelope and selects for mutations in Lsr2

por Báez-Ramírez, Estalina, Querales, Luis, Aranaga, Carlos Andres, López, Gustavo, Guerrero, Elba, Kremer, Laurent, Carrère-Kremer, Séverine, Viljoen, Albertus, Daffé, Mamadou, Laval, Françoise, Cole, Stewart T., Benjak, Andrej, Alzari, Pedro, André-Leroux, Gwenaëlle, Jacobs, William R., Vilcheze, Catherine, Takiff, Howard E.
Publicado 2021

Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (ABC) transporter Rv1747 to regulate mycobacterial growth

por Glass, Lisa N., Swapna, Ganduri, Chavadi, Sivagami Sundaram, Tufariello, JoAnn M., Mi, Kaixia, Drumm, Joshua E., Lam, TuKiet T., Zhu, Guofeng, Zhan, Chenyang, Vilchéze, Catherine, Arcos, Jesus, Chen, Yong, Bi, Lijun, Mehta, Simren, Porcelli, Steven A., Almo, Steve C., Yeh, Syun-Ru, Jacobs, William R., Torrelles, Jordi B., Chan, John
Publicado 2017

Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes

por Liu, Renhe, Lyu, Xiaoxuan, Batt, Sarah M, Hsu, Mei‐Hui, Harbut, Michael B, Vilchèze, Catherine, Cheng, Bo, Ajayi, Kehinde, Yang, Baiyuan, Yang, Yun, Guo, Hui, Lin, Changyou, Gan, Fei, Wang, Chen, Franzblau, Scott G., Jacobs, William R., Besra, Gurdyal S., Johnson, Eric F., Petrassi, Mike, Chatterjee, Arnab K., Fütterer, Klaus, Wang, Feng
Publicado 2017