A response‐adaptive randomization procedure for multi‐armed clinical trials with normally distributed outcomes

por Williamson, S. Faye, Villar, Sofía S.
Publicado 2019

Bayesian adaptive bandit-based designs using the Gittins index for multi-armed trials with normally distributed endpoints

por Smith, Adam L., Villar, Sofía S.
Publicado 2017

Covariate-Adjusted Response-Adaptive Randomization for Multi-Arm Clinical Trials Using a Modified Forward Looking Gittins Index Rule

por Villar, Sofía S., Rosenberger, William F.
Publicado 2017

Revisiting the multi-armed bandit model for the optimal design of clinical trials: benefits and drawbacks

por Villar, Sofia S, Bowden, Jack, Wason, James
Publicado 2013

Patient drift and response-adaptive randomisation: impact and solutions

por Villar, Sofia S, Wason, James, Bowden, Jack
Publicado 2015

Response‐adaptive designs for binary responses: How to offer patient benefit while being robust to time trends?

por Villar, Sofía S., Bowden, Jack, Wason, James
Publicado 2017

A Bayesian adaptive design for clinical trials in rare diseases

por Williamson, S. Faye, Jacko, Peter, Villar, Sofía S., Jaki, Thomas
Publicado 2017

Response adaptive intervention allocation in stepped‐wedge cluster randomized trials

por Grayling, Michael J., Wason, James M. S., Villar, Sofía S.
Publicado 2022

A novel statistical test for treatment differences in clinical trials using a response-adaptive forward-looking Gittins Index Rule

por Barnett, Helen Yvette, Villar, Sofía S., Geys, Helena, Jaki, Thomas
Publicado 2021

Some performance considerations when using multi-armed bandit algorithms in the presence of missing data

por Chen, Xijin, Lee, Kim May, Villar, Sofia S., Robertson, David S.
Publicado 2022

The performance of the National Early Warning Score in hospitalised patients infected by Covid-19

por Villar, Sofia S., Machiwenyika, Judith M.T., Zhu, Yajing, Mackay, Jonathan H.
Publicado 2021

Trajectories of vital signs in patients with Covid-19

por Machiwenyika, Judith M.T., Zhu, Yajing, Villar, Sofia S., Mackay, Jonathan H.
Publicado 2021

Quantifying Efficiency Gains of Innovative Designs of Two-Arm Vaccine Trials for COVID-19 Using an Epidemic Simulation Model

por Johnson, Rob, Jackson, Chris, Presanis, Anne, Villar, Sofia S., De Angelis, Daniela
Publicado 2022

Response-adaptive randomization in clinical trials: from myths to practical considerations

por Robertson, David S., Lee, Kim May, López-Kolkovska, Boryana C., Villar, Sofía S.
Publicado 2023

Effect of hypoxemia on outcome in respiratory failure supported with extracorporeal membrane oxygenation: a cardinality matched cohort study

por Warren, Alex, McKie, Mikel A., Villar, Sofía S., Camporota, Luigi, Vuylsteke, Alain
Publicado 2022

Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs

por Burnett, Thomas, Mozgunov, Pavel, Pallmann, Philip, Villar, Sofia S., Wheeler, Graham M., Jaki, Thomas
Publicado 2020

Effect of high-flow nasal therapy on patient-centred outcomes in patients at high risk of postoperative pulmonary complications after cardiac surgery: a statistical analysis plan f...

por Dawson, Sarah N., Chiu, Yi-Da, Klein, Andrew A., Earwaker, Melissa, Villar, Sofia S.
Publicado 2022

Dynamic individual vital sign trajectory early warning score (DyniEWS) versus snapshot national early warning score (NEWS) for predicting postoperative deterioration

por Zhu, Yajing, Chiu, Yi-Da, Villar, Sofia S., Brand, Jonathan W., Patteril, Mathew V., Morrice, David J., Clayton, James, Mackay, Jonathan H.
Publicado 2020

Point OutWords: protocol for a feasibility randomised controlled trial of a motor skills intervention to promote communicative development in non-verbal children with autism

por McKinney, Ailbhe, Hotson, Kathryn L., Rybicki, Alicia, Weisblatt, Emma J. L., Días, Claudia, Foster, Juliet, Villar, Sofía S., Murphy, Suzanne, Belmonte, Matthew K.
Publicado 2020

Optimal protamine dosing after cardiopulmonary bypass: The PRODOSE adaptive randomised controlled trial

por Miles, Lachlan F., Burt, Christiana, Arrowsmith, Joseph, McKie, Mikel A., Villar, Sofia S., Govender, Pooveshnie, Shaylor, Ruth, Tan, Zihui, De Silva, Ravi, Falter, Florian
Publicado 2021