Calmodulin: A Multitasking Protein in Kv7.2 Potassium Channel Functions

por Alaimo, Alessandro, Villarroel, Alvaro
Publicado 2018

Atomistic Insights of Calmodulin Gating of Complete Ion Channels

por Núñez, Eider, Muguruza-Montero, Arantza, Villarroel, Alvaro
Publicado 2020

Microglia-Mediated Inflammation and Neural Stem Cell Differentiation in Alzheimer’s Disease: Possible Therapeutic Role of K(V)1.3 Channel Blockade

por Revuelta, Miren, Urrutia, Janire, Villarroel, Alvaro, Casis, Oscar
Publicado 2022

Structural basis and energy landscape for the Ca(2+) gating and calmodulation of the Kv7.2 K(+) channel

por Bernardo-Seisdedos, Ganeko, Nuñez, Eider, Gomis, Carolina, Malo, Covadonga, Villarroel, Álvaro, Millet, Oscar
Publicado 2018

The Crossroad of Ion Channels and Calmodulin in Disease

por Urrutia, Janire, Aguado, Alejandra, Muguruza-Montero, Arantza, Núñez, Eider, Malo, Covadonga, Casis, Oscar, Villarroel, Alvaro
Publicado 2019

Differential Regulation of PI(4,5)P(2) Sensitivity of Kv7.2 and Kv7.3 Channels by Calmodulin

por Gomis-Perez, Carolina, Soldovieri, Maria V., Malo, Covadonga, Ambrosino, Paolo, Taglialatela, Maurizio, Areso, Pilar, Villarroel, Alvaro
Publicado 2017

Lack of correlation between surface expression and currents in epileptogenic AB-calmodulin binding domain Kv7.2 potassium channel mutants

por Alaimo, Alessandro, Etxeberria, Ainhoa, Gómez-Posada, Juan Camilo, Gomis-Perez, Carolina, Fernández-Orth, Juncal, Malo, Covadonga, Villarroel, Alvaro
Publicado 2018

Calmodulin confers calcium sensitivity to the stability of the distal intracellular assembly domain of Kv7.2 channels

por Alaimo, Alessandro, Nuñez, Eider, Aivar, Paloma, Fernández-Orth, Juncal, Gomis-Perez, Carolina, Bernardo-Seisdedos, Ganeko, Malo, Covadonga, Villarroel, Alvaro
Publicado 2017

Molecular dynamics simulations of the calmodulin-induced α-helix in the SK2 calcium-gated potassium ion channel

por Ramis, Rafael, Ballesteros, Óscar R., Muguruza-Montero, Arantza, M-Alicante, Sara, Núñez, Eider, Villarroel, Álvaro, Leonardo, Aritz, Bergara, Aitor
Publicado 2022

Selective Interaction of Syntaxin 1A with KCNQ2: Possible Implications for Specific Modulation of Presynaptic Activity

por Regev, Noa, Degani-Katzav, Nurit, Korngreen, Alon, Etzioni, Adi, Siloni, Sivan, Alaimo, Alessandro, Chikvashvili, Dodo, Villarroel, Alvaro, Attali, Bernard, Lotan, Ilana
Publicado 2009

Pivoting between Calmodulin Lobes Triggered by Calcium in the Kv7.2/Calmodulin Complex

por Alaimo, Alessandro, Alberdi, Araitz, Gomis-Perez, Carolina, Fernández-Orth, Juncal, Bernardo-Seisdedos, Ganeko, Malo, Covadonga, Millet, Oscar, Areso, Pilar, Villarroel, Alvaro
Publicado 2014

Novel Dominant KCNQ2 Exon 7 Partial In-Frame Duplication in a Complex Epileptic and Neurodevelopmental Delay Syndrome

por Lazo, Pedro A., García, Juan L., Gómez-Puertas, Paulino, Marcos-Alcalde, Íñigo, Arjona, Cesar, Villarroel, Alvaro, González-Sarmiento, Rogelio, Fons, Carmen
Publicado 2020

Surface Expression and Subunit Specific Control of Steady Protein Levels by the Kv7.2 Helix A-B Linker

por Aivar, Paloma, Fernández-Orth, Juncal, Gomis-Perez, Carolina, Alberdi, Araitz, Alaimo, Alessandro, Rodríguez, Manuel S., Giraldez, Teresa, Miranda, Pablo, Areso, Pilar, Villarroel, Alvaro
Publicado 2012

Redox regulation of K(V)7 channels through EF3 hand of calmodulin

por Nuñez, Eider, Jones, Frederick, Muguruza-Montero, Arantza, Urrutia, Janire, Aguado, Alejandra, Malo, Covadonga, Bernardo-Seisdedos, Ganeko, Domene, Carmen, Millet, Oscar, Gamper, Nikita, Villarroel, Alvaro
Publicado 2023

Do calmodulin binding IQ motifs have built‐in capping domains?

por Muguruza‐Montero, Arantza, Ramis, Rafael, Nuñez, Eider, R. Ballesteros, Oscar, G. Ibarluzea, Markel, Araujo, Ariane, M‐Alicante, Sara, Urrutia, Janire, Leonardo, Aritz, Bergara, Aitor, Villarroel, Alvaro
Publicado 2021

Kv7 Channels Can Function without Constitutive Calmodulin Tethering

por Gómez-Posada, Juan Camilo, Aivar, Paloma, Alberdi, Araitz, Alaimo, Alessandro, Etxeberría, Ainhoa, Fernández-Orth, Juncal, Zamalloa, Teresa, Roura-Ferrer, Meritxell, Villace, Patricia, Areso, Pilar, Casis, Oscar, Villarroel, Alvaro
Publicado 2011

Correction: Kv7 Channels Can Function without Constitutive Calmodulin Tethering

por Gómez-Posada, Juan Camilo, Aivar, Paloma, Alberdi, Araitz, Alaimo, Alessandro, Etxeberría, Ainhoa, Fernández-Orth, Juncal, Zamalloa, Teresa, Roura-Ferrer, Meritxell, Villace, Patricia, Areso, Pilar, Casis, Oscar, Villarroel, Alvaro
Publicado 2014

An epilepsy-causing mutation leads to co-translational misfolding of the Kv7.2 channel

por Urrutia, Janire, Aguado, Alejandra, Gomis-Perez, Carolina, Muguruza-Montero, Arantza, Ballesteros, Oscar R., Zhang, Jiaren, Nuñez, Eider, Malo, Covadonga, Chung, Hee Jung, Leonardo, Aritz, Bergara, Aitor, Villarroel, Alvaro
Publicado 2021

Dynamic properties of calcium-activated chloride currents in Xenopus laevis oocytes

por M. De la Fuente, Ildefonso, Malaina, Iker, Pérez-Samartín, Alberto, Boyano, María Dolores, Pérez-Yarza, Gorka, Bringas, Carlos, Villarroel, Álvaro, Fedetz, María, Arellano, Rogelio, Cortes, Jesus M., Martínez, Luis
Publicado 2017

Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors

por Alaimo, Alessandro, Lorenzoni, Marco, Ambrosino, Paolo, Bertossi, Arianna, Bisio, Alessandra, Macchia, Alice, Zoni, Eugenio, Genovesi, Sacha, Cambuli, Francesco, Foletto, Veronica, De Felice, Dario, Soldovieri, Maria Virginia, Mosca, Ilaria, Gandolfi, Francesco, Brunelli, Matteo, Petris, Gianluca, Cereseto, Anna, Villarroel, Alvaro, Thalmann, George, Carbone, Francesco Giuseppe, Kruithof-de Julio, Marianna, Barbareschi, Mattia, Romanel, Alessandro, Taglialatela, Maurizio, Lunardi, Andrea
Publicado 2020