Oncogenic RAS-induced CK1α drives nuclear FOXO proteolysis

por Zhang, F, Virshup, D M, Cheong, J K
Publicado 2018

IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ɛ and Wnt/β-catenin independent inhibition of mitotic spindle formation

por Cheong, J K, Hung, N T, Wang, H, Tan, P, Voorhoeve, P M, Lee, S H, Virshup, D M
Publicado 2011

FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway

por Asad, M, Wong, M K, Tan, T Z, Choolani, M, Low, J, Mori, S, Virshup, D, Thiery, J P, Huang, R Y-J
Publicado 2014

Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer

por Coombs, G S, Schmitt, A A, Canning, C A, Alok, A, Low, I C C, Banerjee, N, Kaur, S, Utomo, V, Jones, C M, Pervaiz, S, Toone, E J, Virshup, D M
Publicado 2012

Distinct routes to metastasis: plasticity-dependent and plasticity-independent pathways

por Somarelli, J A, Schaeffer, D, Marengo, M S, Bepler, T, Rouse, D, Ware, K E, Hish, A J, Zhao, Y, Buckley, A F, Epstein, J I, Armstrong, A J, Virshup, D M, Garcia-Blanco, M A
Publicado 2016

Wnt addiction of genetically defined cancers reversed by PORCN inhibition

por Madan, B, Ke, Z, Harmston, N, Ho, S Y, Frois, A O, Alam, J, Jeyaraj, D A, Pendharkar, V, Ghosh, K, Virshup, I H, Manoharan, V, Ong, E H Q, Sangthongpitag, K, Hill, J, Petretto, E, Keller, T H, Lee, M A, Matter, A, Virshup, D M
Publicado 2016