Beyond the synucleinopathies: alpha synuclein as a driving force in neurodegenerative comorbidities

por Visanji, Naomi P., Lang, Anthony E., Kovacs, Gabor G.
Publicado 2019

The prion hypothesis in Parkinson's disease: Braak to the future

por Visanji, Naomi P, Brooks, Patricia L, Hazrati, Lili-Naz, Lang, Anthony E
Publicado 2013

WHAT’S OLD IS NEW: USING ARTIFICIAL INTELLIGENCE TO ACCELERATE DISCOVERY OF NEW TREATMENTS

por Marras, Connie, Maclagan, Laura C, Cheng, Yi, Visanji, Naomi, Tadrous, Mina, Bronskill, Susan E
Publicado 2019

Alpha-Synuclein Targeting Therapeutics for Parkinson's Disease and Related Synucleinopathies

por Menon, Sindhu, Armstrong, Sabrina, Hamzeh, Amir, Visanji, Naomi P., Sardi, Sergio Pablo, Tandon, Anurag
Publicado 2022

Tumor Necrosis Factor-α Underlies Loss of Cortical Dendritic Spine Density in a Mouse Model of Congestive Heart Failure

por Meissner, Anja, Visanji, Naomi P, Momen, M Abdul, Feng, Rui, Francis, Beverly M, Bolz, Steffen-Sebastian, Hazrati, Lili-Naz
Publicado 2015

Deep brain stimulation of the subthalamic nucleus preferentially alters the translational profile of striatopallidal neurons in an animal model of Parkinson's disease

por Visanji, Naomi P., Kamali Sarvestani, Iman, Creed, Meaghan C., Shams Shoaei, Zahra, Nobrega, José N., Hamani, Clement, Hazrati, Lili-Naz
Publicado 2015

An AI-guided screen identifies probucol as an enhancer of mitophagy through modulation of lipid droplets

por Moskal, Natalia, Visanji, Naomi P., Gorbenko, Olena, Narasimhan, Vijay, Tyrrell, Hannah, Nash, Jess, Lewis, Peter N., McQuibban, G. Angus
Publicado 2023

Differential regulation of wild-type and mutant alpha-synuclein binding to synaptic membranes by cytosolic factors

por Wislet-Gendebien, Sabine, Visanji, Naomi P, Whitehead, Shawn N, Marsilio, Diana, Hou, Weimin, Figeys, Daniel, Fraser, Paul E, Bennett, Steffany AL, Tandon, Anurag
Publicado 2008

AAV1/2-induced overexpression of A53T-α-synuclein in the substantia nigra results in degeneration of the nigrostriatal system with Lewy-like pathology and motor impairment: a new m...

por Ip, Chi Wang, Klaus, Laura-Christin, Karikari, Akua A., Visanji, Naomi P., Brotchie, Jonathan M., Lang, Anthony E., Volkmann, Jens, Koprich, James B.
Publicado 2017

Retraction Note to: Differential regulation of wild-type and mutant alpha-synuclein binding to synaptic membranes by cytosolic factors

por Wislet-Gendebien, Sabine, Visanji, Naomi P., Whitehead, Shawn N., Marsilio, Diana, Hou, Weimin, Figeys, Daniel, Fraser, Paul E., Bennett, Steffany A. L., Tandon, Anurag
Publicado 2021

Alpha-synuclein seeding shows a wide heterogeneity in multiple system atrophy

por Martinez-Valbuena, Ivan, Visanji, Naomi P., Kim, Ain, Lau, Heather H. C., So, Raphaella W. L., Alshimemeri, Sohaila, Gao, Andrew, Seidman, Michael A., Luquin, Maria R., Watts, Joel C., Lang, Anthony E., Kovacs, Gabor G.
Publicado 2022

α-Synuclein Strains Target Distinct Brain Regions and Cell Types

por Lau, Angus, So, Raphaella W.L., Lau, Heather H.C., Sang, Jason C., Ruiz-Riquelme, Alejandro, Fleck, Shelaine C., Stuart, Erica, Menon, Sindhu, Visanji, Naomi P., Meisl, Georg, Faidi, Rania, Marano, Maria M., Schmitt-Ulms, Cian, Wang, Zhilan, Fraser, Paul E., Tandon, Anurag, Hyman, Bradley T., Wille, Holger, Ingelsson, Martin, Klenerman, David, Watts, Joel C.
Publicado 2019

Axial Impairment Following Deep Brain Stimulation in Parkinson’s Disease: A Surgicogenomic Approach

por Visanji, Naomi P., Ghani, Mahdi, Yu, Eric, Kakhki, Erfan Ghani, Sato, Christine, Moreno, Danielle, Naranian, Taline, Poon, Yu-Yan, Abdollahi, Maryam, Naghibzadeh, Maryam, Rajalingam, Rajasumi, Lozano, Andres M., Kalia, Suneil K., Hodaie, Mojgan, Cohn, Melanie, Statucka, Marta, Boutet, Alexandre, Elias, Gavin J.B., Germann, Jürgen, Munhoz, Renato, Lang, Anthony E., Gan-Or, Ziv, Rogaeva, Ekaterina, Fasano, Alfonso
Publicado 2022

Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans

por Chen, Kevin S., Menezes, Krystal, Rodgers, Jarlath B., O’Hara, Darren M., Tran, Nhat, Fujisawa, Kazuko, Ishikura, Seiya, Khodaei, Shahin, Chau, Hien, Cranston, Anna, Kapadia, Minesh, Pawar, Grishma, Ping, Susan, Krizus, Aldis, Lacoste, Alix, Spangler, Scott, Visanji, Naomi P., Marras, Connie, Majbour, Nour K., El-Agnaf, Omar M. A., Lozano, Andres M., Culotti, Joseph, Suo, Satoshi, Ryu, William S., Kalia, Suneil K., Kalia, Lorraine V.
Publicado 2021

Genomewide Association Studies of LRRK2 Modifiers of Parkinson's Disease

por Lai, Dongbing, Alipanahi, Babak, Fontanillas, Pierre, Schwantes‐An, Tae‐Hwi, Aasly, Jan, Alcalay, Roy N., Beecham, Gary W., Berg, Daniela, Bressman, Susan, Brice, Alexis, Brockman, Kathrin, Clark, Lorraine, Cookson, Mark, Das, Sayantan, Van Deerlin, Vivianna, Follett, Jordan, Farrer, Matthew J., Trinh, Joanne, Gasser, Thomas, Goldwurm, Stefano, Gustavsson, Emil, Klein, Christine, Lang, Anthony E., Langston, J. William, Latourelle, Jeanne, Lynch, Timothy, Marder, Karen, Marras, Connie, Martin, Eden R., McLean, Cory Y., Mejia‐Santana, Helen, Molho, Eric, Myers, Richard H., Nuytemans, Karen, Ozelius, Laurie, Payami, Haydeh, Raymond, Deborah, Rogaeva, Ekaterina, Rogers, Michael P., Ross, Owen A., Samii, Ali, Saunders‐Pullman, Rachel, Schüle, Birgitt, Schulte, Claudia, Scott, William K., Tanner, Caroline, Tolosa, Eduardo, Tomkins, James E., Vilas, Dolores, Trojanowski, John Q., Uitti, Ryan, Vance, Jeffery M., Visanji, Naomi P., Wszolek, Zbigniew K., Zabetian, Cyrus P., Mirelman, Anat, Giladi, Nir, Orr Urtreger, Avi, Cannon, Paul, Fiske, Brian, Foroud, Tatiana
Publicado 2021