Effects of PTEN Loss and Activated KRAS Overexpression on Mechanical Properties of Breast Epithelial Cells

por Linthicum, Will, Thanh, Minh-Tri Ho, Vitolo, Michele I., Wen, Qi
Publicado 2018

Gauging the Impact of Cancer Treatment Modalities on Circulating Tumor Cells (CTCs)

por Mathias, Trevor J., Chang, Katarina T., Martin, Stuart S., Vitolo, Michele I.
Publicado 2020

Distinct roles of tumor associated mutations in collective cell migration

por Lee, Rachel M., Vitolo, Michele I., Losert, Wolfgang, Martin, Stuart S.
Publicado 2021

Loss of the obscurin-RhoGEF downregulates RhoA signaling and increases microtentacle formation and attachment of breast epithelial cells

por Perry, Nicole A., Vitolo, Michele I., Martin, Stuart S., Kontrogianni-Konstantopoulos, Aikaterini
Publicado 2014

Long Noncoding RNA DANCR Activates Wnt/β-Catenin Signaling through MiR-216a Inhibition in Non-Small Cell Lung Cancer

por Yu, Justine E., Ju, Julia A., Musacchio, Nicholas, Mathias, Trevor J., Vitolo, Michele I.
Publicado 2020

Parthenolide and costunolide reduce microtentacles and tumor cell attachment by selectively targeting detyrosinated tubulin independent from NF-κB inhibition

por Whipple, Rebecca A, Vitolo, Michele I, Boggs, Amanda E, Charpentier, Monica S, Thompson, Keyata, Martin, Stuart S
Publicado 2013

Label-free cell tracking enables collective motion phenotyping in epithelial monolayers

por Gu, Shuyao, Lee, Rachel M., Benson, Zackery, Ling, Chenyi, Vitolo, Michele I., Martin, Stuart S., Chalfoun, Joe, Losert, Wolfgang
Publicado 2022

ROCK inhibition promotes microtentacles that enhance reattachment of breast cancer cells

por Bhandary, Lekhana, Whipple, Rebecca A., Vitolo, Michele I., Charpentier, Monica S., Boggs, Amanda E., Chakrabarti, Kristi R., Thompson, Keyata N., Martin, Stuart S.
Publicado 2015

Pharmacologic regulation of AMPK in breast cancer affects cytoskeletal properties involved with microtentacle formation and re-attachment

por Chakrabarti, Kristi R., Whipple, Rebecca A., Boggs, Amanda E., Hessler, Lindsay K., Bhandary, Lekhana, Vitolo, Michele I., Thompson, Keyata, Martin, Stuart S.
Publicado 2015

Overexpressing TPTE2 (TPIP), a homolog of the human tumor suppressor gene PTEN, rescues the abnormal phenotype of the PTEN(−/−) mutant

por Lusche, Daniel F., Buchele, Emma C., Russell, Kanoe B., Soll, Benjamin A., Vitolo, Michele I., Klemme, Michael R., Wessels, Deborah J., Soll, David R.
Publicado 2018

Single-Cell Tracking of Breast Cancer Cells Enables Prediction of Sphere Formation from Early Cell Divisions

por Bailey, Patrick C., Lee, Rachel M., Vitolo, Michele I., Pratt, Stephen J.P., Ory, Eleanor, Chakrabarti, Kristi, Lee, Cornell J., Thompson, Keyata N., Martin, Stuart S.
Publicado 2018

The combinatorial activation of the PI3K and Ras/MAPK pathways is sufficient for aggressive tumor formation, while individual pathway activation supports cell persistence

por Thompson, Keyata N., Whipple, Rebecca A., Yoon, Jennifer R., Lipsky, Michael, Charpentier, Monica S., Boggs, Amanda E., Chakrabarti, Kristi R., Bhandary, Lekhana, Hessler, Lindsay K., Martin, Stuart S., Vitolo, Michele I.
Publicado 2015

Inhibition of ovarian tumor cell invasiveness by targeting SYK in tyrosine kinase signaling pathway

por Yu, Yu, Rahmanto, Yohan Suryo, Lee, Meng-Horng, Wu, Pei-Hsun, Phillip, Jude M., Huang, Chuan-Hsiang, Vitolo, Michele I., Gaillard, Stephanie, Martin, Stuart S., Wirtz, Denis, Shih, Ie-Ming, Wang, Tian-Li
Publicado 2018

Hydrogen Peroxide Induces α-Tubulin Detyrosination and Acetylation and Impacts Breast Cancer Metastatic Phenotypes

por Stemberger, Megan B., Ju, Julia A., Thompson, Keyata N., Mathias, Trevor J., Jerrett, Alexandra E., Chang, Katarina T., Ory, Eleanor C., Annis, David A., Mull, Makenzy L., Gilchrist, Darin E., Vitolo, Michele I., Martin, Stuart S.
Publicado 2023

Elevation of Cytoplasmic Calcium Suppresses Microtentacle Formation and Function in Breast Tumor Cells

por Chang, Katarina T., Thompson, Keyata N., Pratt, Stephen J. P., Ju, Julia A., Lee, Rachel M., Mathias, Trevor J., Mull, Makenzy L., Annis, David A., Ory, Eleanor C., Stemberger, Megan B., Vitolo, Michele I., Martin, Stuart S.
Publicado 2023

A microfluidic assay for the quantification of the metastatic propensity of breast-cancer specimens

por Yankaskas, Christopher L., Thompson, Keyata N., Paul, Colin D., Vitolo, Michele I., Mistriotis, Panagiotis, Mahendra, Ankit, Bajpai, Vivek K., Shea, Daniel J., Manto, Kristen M., Chai, Andreas C., Varadarajan, Navin, Kontrogianni-Konstantopoulos, Aikaterini, Martin, Stuart S., Konstantopoulos, Konstantinos
Publicado 2019

Tubulin Carboxypeptidase Activity Promotes Focal Gelatin Degradation in Breast Tumor Cells and Induces Apoptosis in Breast Epithelial Cells That Is Overcome by Oncogenic Signaling

por Mathias, Trevor J., Ju, Julia A., Lee, Rachel M., Thompson, Keyata N., Mull, Makenzy L., Annis, David A., Chang, Katarina T., Ory, Eleanor C., Stemberger, Megan B., Hotta, Takashi, Ohi, Ryoma, Vitolo, Michele I., Moutin, Marie-Jo, Martin, Stuart S.
Publicado 2022

Lipid tethering of breast tumor cells reduces cell aggregation during mammosphere formation

por Bhandary, Lekhana, Bailey, Patrick C., Chang, Katarina T., Underwood, Karen F., Lee, Cornell J., Whipple, Rebecca A., Jewell, Christopher M., Ory, Eleanor, Thompson, Keyata N., Ju, Julia A., Mathias, Trevor M., Pratt, Stephen J. P., Vitolo, Michele I., Martin, Stuart S.
Publicado 2021

Microtubule disruption reduces metastasis more effectively than primary tumor growth

por Thompson, Keyata N., Ju, Julia A., Ory, Eleanor C., Pratt, Stephen J. P., Lee, Rachel M., Mathias, Trevor J., Chang, Katarina T., Lee, Cornell J., Goloubeva, Olga G., Bailey, Patrick C., Chakrabarti, Kristi R., Jewell, Christopher M., Vitolo, Michele I., Martin, Stuart S.
Publicado 2022

Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming

por Suryo Rahmanto, Yohan, Shen, Wenjing, Shi, Xu, Chen, Xi, Yu, Yu, Yu, Zheng-Cheng, Miyamoto, Tsutomu, Lee, Meng-Horng, Singh, Vivek, Asaka, Ryoichi, Shimberg, Geoffrey, Vitolo, Michele I., Martin, Stuart S., Wirtz, Denis, Drapkin, Ronny, Xuan, Jianhua, Wang, Tian-Li, Shih, Ie-Ming
Publicado 2020