A phospho-proteomic study of cetuximab resistance in KRAS/NRAS/BRAF(V600) wild-type colorectal cancer

por Georgiou, Alexandros, Stewart, Adam, Vlachogiannis, Georgios, Pickard, Lisa, Valeri, Nicola, Cunningham, David, Whittaker, Steven R., Banerji, Udai
Publicado 2021

The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis

por Vlachogiannis, Georgios, Niederhuth, Chad E., Tuna, Salih, Stathopoulou, Athanasia, Viiri, Keijo, de Rooij, Dirk G., Jenner, Richard G., Schmitz, Robert J., Ooi, Steen K.T.
Publicado 2015

The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis

por Vlachogiannis, Georgios, Niederhuth, Chad E., Tuna, Salih, Stathopoulou, Athanasia, Viiri, Keijo, de Rooij, Dirk G., Jenner, Richard G., Schmitz, Robert J., Ooi, Steen K.T.
Publicado 2015

USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development

por Novellasdemunt, Laura, Kucharska, Anna, Baulies, Anna, Hutton, Colin, Vlachogiannis, Georgios, Repana, Dimitra, Rowan, Andrew, Suárez-Bonnet, A., Ciccarelli, Francesca, Valeri, Nicola, Li, Vivian S.W.
Publicado 2023

Exploiting evolutionary steering to induce collateral drug sensitivity in cancer

por Acar, Ahmet, Nichol, Daniel, Fernandez-Mateos, Javier, Cresswell, George D., Barozzi, Iros, Hong, Sung Pil, Trahearn, Nicholas, Spiteri, Inmaculada, Stubbs, Mark, Burke, Rosemary, Stewart, Adam, Caravagna, Giulio, Werner, Benjamin, Vlachogiannis, Georgios, Maley, Carlo C., Magnani, Luca, Valeri, Nicola, Banerji, Udai, Sottoriva, Andrea
Publicado 2020

MIR21-induced loss of junctional adhesion molecule A promotes activation of oncogenic pathways, progression and metastasis in colorectal cancer

por Lampis, Andrea, Hahne, Jens C., Gasparini, Pierluigi, Cascione, Luciano, Hedayat, Somaieh, Vlachogiannis, Georgios, Murgia, Claudio, Fontana, Elisa, Edwards, Joanne, Horgan, Paul G., Terracciano, Luigi, Sansom, Owen J., Martins, Carlos D., Kramer-Marek, Gabriela, Croce, Carlo M., Braconi, Chiara, Fassan, Matteo, Valeri, Nicola
Publicado 2021

Suppression of interferon gene expression overcomes resistance to MEK inhibition in KRAS-mutant colorectal cancer

por Wagner, Steve, Vlachogiannis, Georgios, De Haven Brandon, Alexis, Valenti, Melanie, Box, Gary, Jenkins, Liam, Mancusi, Caterina, Self, Annette, Manodoro, Floriana, Assiotis, Ioannis, Robinson, Penny, Chauhan, Ritika, Rust, Alistair G., Matthews, Nik, Eason, Kate, Khan, Khurum, Starling, Naureen, Cunningham, David, Sadanandam, Anguraj, Isacke, Clare M., Kirkin, Vladimir, Valeri, Nicola, Whittaker, Steven R.
Publicado 2018

Correction: Suppression of interferon gene expression overcomes resistance to MEK inhibition in KRAS-mutant colorectal cancer

por Wagner, Steve, Vlachogiannis, Georgios, De Haven Brandon, Alexis, Valenti, Melanie, Box, Gary, Jenkins, Liam, Mancusi, Caterina, Self, Annette, Manodoro, Floriana, Assiotis, Ioannis, Robinson, Penny, Chauhan, Ritika, Rust, Alistair G., Matthews, Nik, Eason, Kate, Khan, Khurum, Starling, Naureen, Cunningham, David, Sadanandam, Anguraj, Isacke, Clare M., Kirkin, Vladimir, Valeri, Nicola, Whittaker, Steven R.
Publicado 2019

Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy

por Tajan, Mylène, Hennequart, Marc, Cheung, Eric C., Zani, Fabio, Hock, Andreas K., Legrave, Nathalie, Maddocks, Oliver D. K., Ridgway, Rachel A., Athineos, Dimitris, Suárez-Bonnet, Alejandro, Ludwig, Robert L., Novellasdemunt, Laura, Angelis, Nikolaos, Li, Vivian S. W., Vlachogiannis, Georgios, Valeri, Nicola, Mainolfi, Nello, Suri, Vipin, Friedman, Adam, Manfredi, Mark, Blyth, Karen, Sansom, Owen J., Vousden, Karen H.
Publicado 2021

A MYC/GCN2/eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer

por Schmidt, Stefanie, Gay, David, Uthe, Friedrich Wilhelm, Denk, Sarah, Paauwe, Madelon, Matthes, Niels, Diefenbacher, Markus Elmar, Bryson, Sheila, Warrander, Fiona Clare, Erhard, Florian, Ade, Carsten Patrick, Baluapuri, Apoorva, Walz, Susanne, Jackstadt, Rene, Ford, Catriona, Vlachogiannis, Georgios, Valeri, Nicola, Otto, Christoph, Schülein-Völk, Christina, Maurus, Katja, Schmitz, Werner, Knight, John Raymond Philip, Wolf, Elmar, Strathdee, Douglas, Schulze, Almut, Germer, Christoph-Thomas, Rosenwald, Andreas, Sansom, Owen James, Eilers, Martin, Wiegering, Armin
Publicado 2019

EGFR amplification and outcome in a randomised phase III trial of chemotherapy alone or chemotherapy plus panitumumab for advanced gastro-oesophageal cancers

por Smyth, Elizabeth C, Vlachogiannis, Georgios, Hedayat, Somaieh, Harbery, Alice, Hulkki-Wilson, Sanna, Salati, Massimiliano, Kouvelakis, Kyriakos, Fernandez-Mateos, Javier, Cresswell, George D, Fontana, Elisa, Seidlitz, Therese, Peckitt, Clare, Hahne, Jens C, Lampis, Andrea, Begum, Ruwaida, Watkins, David, Rao, Sheela, Starling, Naureen, Waddell, Tom, Okines, Alicia, Crosby, Tom, Mansoor, Was, Wadsley, Jonathan, Middleton, Gary, Fassan, Matteo, Wotherspoon, Andrew, Braconi, Chiara, Chau, Ian, Vivanco, Igor, Sottoriva, Andrea, Stange, Daniel E, Cunningham, David, Valeri, Nicola
Publicado 2021

MIR21 Drives Resistance to Heat Shock Protein 90 Inhibition in Cholangiocarcinoma

por Lampis, Andrea, Carotenuto, Pietro, Vlachogiannis, Georgios, Cascione, Luciano, Hedayat, Somaieh, Burke, Rosemary, Clarke, Paul, Bosma, Else, Simbolo, Michele, Scarpa, Aldo, Yu, Sijia, Cole, Rebecca, Smyth, Elizabeth, Mateos, Javier Fernández, Begum, Ruwaida, Hezelova, Blanka, Eltahir, Zakaria, Wotherspoon, Andrew, Fotiadis, Nicos, Bali, Maria Antonietta, Nepal, Chirag, Khan, Khurum, Stubbs, Mark, Hahne, Jens C., Gasparini, Pierluigi, Guzzardo, Vincenza, Croce, Carlo M., Eccles, Suzanne, Fassan, Matteo, Cunningham, David, Andersen, Jesper B., Workman, Paul, Valeri, Nicola, Braconi, Chiara
Publicado 2018

Modulation of Biliary Cancer Chemo‐Resistance Through MicroRNA‐Mediated Rewiring of the Expansion of CD133+ Cells

por Carotenuto, Pietro, Hedayat, Somaieh, Fassan, Matteo, Cardinale, Vincenzo, Lampis, Andrea, Guzzardo, Vincenza, Vicentini, Caterina, Scarpa, Aldo, Cascione, Luciano, Costantini, Daniele, Carpino, Guido, Alvaro, Domenico, Ghidini, Michele, Trevisani, Francesco, Te Poele, Robert, Salati, Massimiliano, Ventura, Sofia, Vlachogiannis, Georgios, Hahne, Jens C., Boulter, Luke, Forbes, Stuart J., Guest, Rachel V., Cillo, Umberto, Said‐Huntingford, Ian, Begum, Ruwaida, Smyth, Elizabeth, Michalarea, Vasiliki, Cunningham, David, Rimassa, Lorenza, Santoro, Armando, Roncalli, Massimo, Kirkin, Vladimir, Clarke, Paul, Workman, Paul, Valeri, Nicola, Braconi, Chiara
Publicado 2020